Chronic treatment with fluoxetine decreases seizure threshold in naïve but not in rats exposed to the learned helplessness paradigm: Correlation with the hippocampal glutamate release

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 29, Issue 5, 2005, Pages 678-686

  Ferrero, Alejandro J ^a,b   Cereseto, Marina ^a   Reinés, Analía ^a,b   Bonavita, Carla D ^a   Sifonios, Laura L ^a   Rubio, Modesto C ^a,b   Wikinski, Silvia I ^a,b  

^a Instituto de Investigaciones Farmacologicas   (Argentina)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Chronic treatment; Fluoxetine; Glutamate release; Hippocampus; Learned helplessness; Seizure threshold

Indexed keywords

DIZOCILPINE; FLUOXETINE; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PENTETRAZOLE; POTASSIUM; SEROTONIN UPTAKE INHIBITOR; TRITIUM;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DEPRESSION; DRUG EFFICACY; DRUG MECHANISM; HIPPOCAMPUS; IN VITRO STUDY; LEARNED HELPLESSNESS; LONG TERM CARE; MALE; NEUROTOXICITY; NEUROTRANSMISSION; NEUROTRANSMITTER RELEASE; NONHUMAN; RAT; RECEPTOR BINDING; SEIZURE SUSCEPTIBILITY; SEIZURE THRESHOLD;

ANIMALS; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; BEHAVIOR, ANIMAL; CONVULSANTS; DIZOCILPINE MALEATE; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID ANTAGONISTS; FLUOXETINE; GLUTAMIC ACID; HELPLESSNESS, LEARNED; HIPPOCAMPUS; MALE; PENTYLENETETRAZOLE; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; SEIZURES; SYNAPTIC TRANSMISSION;

EID: 21244447715     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2005.04.013     Document Type: Article

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