Effect of membrane characteristics on phase separation and domain formation in cholesterol-lipid mixtures

Biophysical Journal

Volumn 88, Issue 2, 2005, Pages 916-924

  Pata, Veena ^a   Dan, Nily ^a  

^a Drexel University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; LIPID; MEMBRANE PROTEIN;

ARTICLE; CHEMICAL INTERACTION; CONCENTRATION RESPONSE; ENERGY TRANSFER; LIPID BILAYER; LIPID COMPOSITION; MATHEMATICAL MODEL; MEMBRANE BIOLOGY; PHASE SEPARATION; ARTIFICIAL MEMBRANE; CELL MEMBRANE; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; COMPUTER SIMULATION; CONFORMATION; DRUG MIXTURE; MACROMOLECULE; MEMBRANE FLUIDITY; PHASE TRANSITION;

CHOLESTEROL; COMPLEX MIXTURES; COMPUTER SIMULATION; LIPID BILAYERS; MACROMOLECULAR SUBSTANCES; MEMBRANE FLUIDITY; MEMBRANE MICRODOMAINS; MEMBRANES, ARTIFICIAL; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PHASE TRANSITION;

EID: 21244446980     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1529/biophysj.104.052241     Document Type: Article

References (82)

1. Aranda-Espinoza, H., A. Herman, N. Dan, P. Pincus, and S. Safran. 1996. Interaction between inclusions embedded in membranes. Biophys. J. 71:648-656.
2. Bach, D., and E. Wachtel. 2003. Phospholipid/cholesterol model membranes: formation of cholesterol crystallites. BBA-Biomembranes. 1610:187-197.
3. Bartolo, D., A. Ajdari, and J. B. Fournier. 2003. Effective interactions between inclusions in complex fluids driven out of equilibrium. Phys. Rev. E. 67:061112.
4. Bartolo, D., and J. B. Fournier. 2003. Elastic interaction between "hard" or "soft" pointwise inclusions on biological membranes. Eur. Phys. J. E. 11:141-146.
5. Bezrukov, S. M. 2000. Functional consequences of lipid packing stress. Curr. Opin. Colloid In. 5:237-243.
6. Biscari, P., and F. Bisi. 2002. Membrane-mediated interactions of rod-like inclusions. Eur. Phys. J. E. 7:381-386.
7. Brown, D. A., and E. London. 1998. Functions of lipid rafts in biological membranes. Annu. Rev. Cell Dev. Biol. 14:111-136.
8. Cantor, R. S. 1997. Lateral pressures in cell membranes: a mechanism for modulation of protein function. J. Phys. Chem. B. 101:1723-1725.
9. Cantor, R. S. 1999a. The influence of membrane lateral pressures on simple geometric models of protein conformational equilibria. Chem. Phys. Lipids. 101:45-56.
10. Cantor, R. S. 1999b. Lipid composition and the lateral pressure profile in bilayers. Biophys. J. 76:2625-2639.
11. Cantor, R. S. 2002. Size distribution of barrel-stave aggregates of membrane peptides. Biophys. J. 82:2520-2525.
12. Chiu, S. W., E. Jakobsson, R. J. Mashl, and H. L. Scott. 2002. Cholesterol-induced modifications in lipid bilayers: a simulation study. Biophys. J. 83:1842-1853.
13. Chiu, S. W., E. Jakobsson, and H. L. Scott. 2001. Combined Monte Carlo and molecular dynamics simulation of hydrated lipid-cholesterol lipid bilayers at low cholesterol concentration. Biophys. J. 80:1104-1114.
14. Crane, J. M., and L. K. Tamm. 2004. Role of cholesterol in the formation and nature of lipid rafts in planar and spherical model membranes. Biophys. J. 86:2965-2979.
15. Dan, N., A. Berman, P. Pincus, and S. A. Safran. 1994. Membrane-induced interactions between inclusions. J. Phys. II. 4:1713-1725.
16. Dan, N., P. Pincus, and S. A. Safran. 1993. Membrane-induced interactions between inclusions. Langmuir. 9:2768-2771.
17. Dan, N., and S. A. Safran. 1995. Solubilization of proteins in membranes. Isr. J. Chem. 35:37-40.
18. Dan, N., and S. A. Safran. 1998. Effect of lipid characteristics on the structure of transmembrane proteins. Biophys. J. 75:1410-1414.
19. Dill, K. A., and S. Bromberg. 2002. Molecular Driving Forces. Garland Science, New York.
20. Epand, R. M., D. W. Hughes, B. G. Saver, N. Borochov, D. Bach, and E. Wachtel. 2003. Novel properties of cholesterol-dioleoylphosphatidylcholine mixtures. BBA-Biomembranes. 1616:196-208.
21. Fattal, D.R., and A. Ben-Shaul. 1995. Lipid chain packing and lipid-protein interaction in membranes. Physica A. 220:192-216.
22. Finegold, L. 1993. Cholesterol in Membrane Models. CRC Press, Boca Raton, FL.
23. Fox, C. 1950. An introduction to the calculus of variations. Oxford Press, Oxford, UK.
24. Gennis, R. B. 1989. Biomembranes: Molecular Structure and Function. Springer-Verlag, New York.
25. Golestanian, R., M. Goulian, and M. Kardar. 1996a. Fluctuation-induced interactions between rods on a membrane. Phys. Rev. E. 54:6725-6734.
26. Golestanian, R., M. Goulian, and M. Kardar. 1996b. Fluctuation-induced interactions between rods on membranes and interfaces. Europhys. Lett. 33:241-245.
27. Goulian, M. 1996. Inclusions in membranes. Curr. Opin. Colloid In. 1:358-361.
28. Goulian, M., R, Bruinsma, and P. Pincus. 1993a. Long-range forces in heterogeneous fluid membranes. Europhys. Lett. 22:145-150.
29. Goulian, M., R. Bruinsma, and P. Pincus. 1993b. Long-range forces in heterogeneous fluid membranes. Europhys. Lett. 23:155-155.
30. Hjort Ipsen, J., G. Karlstrom, O. G. Mourtisen, H. Wennerstrom, and M. J. Zuckermann. 1987. Phase equilibria in the phosphatidylcholine-cholesterol system. BBA-Biomembranes. 905:162-172.
31. Hofsass, C., E. Lindahl, and O. Edholm. 2003. Molecular dynamics simulations of phospholipid bilayers with cholesterol. Biophys. J. 84:2192-2206.
32. Huang, J. 2002. Exploration of molecular interactions in cholesterol superlattices: effect of multibody interactions. Biophys. J. 83:1014-1025.
33. Huang, J. Y., J. T. Buboltz, and G. W. Feigenson. 1999. Maximum solubility of cholesterol in phosphatidylcholine and phosphatidylethanolamine bilayers. BBA-Biomembranes. 1417:89-100.
34. Huang, J. Y., and G. W. Feigenson. 1999. A microscopic interaction model of maximum solubility of cholesterol in lipid bilayers. Biophys. J. 76:2142-2157.
35. Israelachvili, J. N. 1992. Intermolecular and Surface Forces. Academic Press, London.
36. Kessel, A., N. Ben-Tal, and S. May. 2001. Interactions of cholesterol with lipid bilayers: the preferred configuration and fluctuations. Biophys. J. 81:643-658.
37. Lague, P., M. J. Zuckermann, and B. Roux. 2000. Lipid-mediated interactions between intrinsic membrane proteins: a theoretical study based on integral equations. Biophys. J. 79:2867-2879.
38. Lague, P., M. J. Zuckermann, and B. Roux. 2001. Lipid-mediated interactions between intrinsic membrane proteins: dependence on protein size and lipid composition. Biophys. J. 81:276-284.
39. Lipowsky, R. 2002. Domains and rafts in membranes: hidden dimensions of self organization. J. Biol. Phys. 28:195-210.
40. Loura, L. M. S., A. Fedorov, and M. Prieto. 2001a. Exclusion of a cholesterol analog from the cholesterol-rich phase in model membranes. BBA-Biomembranes. 1511:236-243.
41. Loura, L. M. S., A. Fedorov, and M. Prieto. 2001b. Fluid-fluid membrane microheterogeneity: a fluorescence resonance energy transfer study. Biophys. J. 80:776-788.
42. Marcelja, S. 1976. Lipid-mediated protein interactions in membranes. Biophys. Biochim. Acta. 455:1-7.
43. May, S. 2000a. Protein-induced bilayer deformations: the lipid tilt degree of freedom. Eur. Biophys. J. 29:17-28.
44. May, S. 2000b. Theories on structural perturbations of lipid bilayers. Curr. Opin. Colloid In. 5:244-249.
45. May. S. 2002. Membrane perturbations induced by integral proteins: role of conformational restrictions of the lipid chains. Langmuir. 18:6356-6364.
46. II transition. Biophys. J. 76:751-767.
47. May, S., and A. Ben-Shaul. 2000. A molecular model for lipid-mediated interaction between proteins in membranes. Phys. Chem. Chem. Phys. 2:4494-4502.
48. McConnell, H. M., and A. Radhakrishnan. 2003. Condensed complexes of cholesterol and phospholipids. BBA-Biomembranes. 1610:159-173.
49. Milner, S. T., and T. A. Witten. 1988. Bending moduli of polymeric surfactant interfaces. J. Phys-Paris. 49:1951-1962.
50. Mouritsen, O. G., and M. Bloom. 1993. Models of lipid-protein interactions in membranes. Annu. Rev. Biophys. Biomol. Struct. 22:145-171.
51. Nagle, J. F., and S. Tristram-Nagle. 2000. Structure of lipid bilayers. BBA-Rev. Biomembranes. 1469:159-195.
52. Nielsen, C., and O. S. Andersen. 2000. Inclusion-induced bilayer deformations: effects of monolayer equilibrium curvature. Biophys. J. 79:2583-2604.
53. Nielsen, C., M. Goulian, and O. S. Andersen. 1998. Energetics of inclusion-induced bilayer deformations. Biophys. J. 74:1966-1983.
54. Ohvo-Rekila, H., B. Ramstedt, P. Leppimaki, and J. P. Slotte. 2002. Cholesterol interactions with phospholipids in membranes. Prog. Lipid Res. 41:66-97.
55. Pandit, S. A., D. Bostick, and M. L. Berkowitz. 2004. Complexation of phosphatidylcholine lipids with cholesterol. Biophys. J. 86:1345-1356.
56. Pasenkiewicz-Gierula, M., T. Rog, K. Kitamura, and A. Kusumi. 2000. Cholesterol effects on the phosphatidylcholine bilayer polar region: a molecular simulation study. Biophys. J. 78:1376-1389.
57. Pata, V., and N. Dan. 2003. The effect of chain length on protein solubilization in polymer-based vesicles (polymersomes). Biophys. J. 85:2111-2118.
58. Radhakrishnan, A., T. G. Anderson, and H. M. McConnell. 2000. Condensed complexes, rafts, and the chemical activity of cholesterol in membranes. Proc. Natl. Acad. Sci. USA. 97:12422-12427.
59. Radhakrishnan, A., and H. M. McConnell. 1999. Condensed complexes of cholesterol and phospholipids. Biophys. J. 77:1507-1517.
60. Robinson, A., W. Richards, P. Thomas, and M. Harm. 1995. Behavior of cholesterol and its effect on headgroup and chain conformations in lipid bilayers: a molecular dynamics study. Biophys. J. 68:164-170.
61. Scott, H. 1991. Lipid-cholesterol interactions. Monte Carlo simulations and theory. Biophys. J. 59:445-455.
62. Silvius, J. R. 2003. Role of cholesterol in lipid raft formation: lessons from lipid model systems. BBA-Biomembranes. 1610:174-183.
63. Simons, K., and E. Ikonen. 2000. Cell biology: how cells handle cholesterol. Science. 290:1721-1726.
64. Sintes, T., and A. Baumgaertner. 1998. Interaction of wedge-shaped proteins in flat bilayer membranes. J. Phys. Chem. B. 102:7050-7057.
65. Small, D. M. 1980. Cholesterol nucleation and growth in gallstone formation. N. Engl. J. Med. 302:1305-1307.
66. Small, D. M. 1988. Progression and regression of atherosclerotic lesions. Insights from lipid physical biochemistry. Arteriosclerosis. 8:103-129.
67. Smondyrev, A. M., and M. L. Berkowitz. 1999. Structure of dipalmitoyl-phosphatidylcholine/cholesterol bilayer at low and high cholesterol concentrations: molecular dynamics simulation. Biophys. J. 77:2075-2089.
68. Smondyrev, A. M., and M. L. Berkowitz. 2001. Molecular dynamics simulation of the structure of dimyristoylphosphatidylcholine bilayers with cholesterol, ergosterol, and lanosterol. Biophys. J. 80:1649-1658.
69. Szleifer, I., D. Kramer, A. Benshaul, W. M. Gelbart, and S. A. Safran. 1990. Molecular theory of curvature elasticity in surfactant films. J. Chem. Phys. 92:6800-6817.
70. Szleifer, I., D. Kramer, A. Ben-Shaul, D. Roux, and W. M. Gelbart. 1988. Curvature elasticity of pure and mixed surfactant films. Phys. Rev. Lett. 60:1966-1969.
71. Taulier, N., M. Waks, T. Gulik-Krzywicki, and W. Urbach. 2002. interactions between transmembrane proteins embedded in a lamellar phase, stabilized by steric interactions. Europhys. Lett. 59:142-148.
72. Troup, G. M., T. N. Tulenko, S. P. Lee, and S. P. Wrenn. 2003. Detection and characterization of laterally phase separated cholesterol domains in model lipid membranes. Colloid. Surface. B. 29:217-231.
73. Tu, K. C., M. L. Klein, and D. J. Tobias. 1998. Constant-pressure molecular dynamics investigation of cholesterol effects in a dipalmitoylphosphatidylcholine bilayer. Biophys. J. 75:2147-2156.
74. Veatch, S. L., and S. L. Keller. 2002. Organization in lipid membranes containing cholesterol. Phys. Rev. Lett. 89:268101-268104.
75. Veatch, S. L., I. V. Polozov, K. Gawrisch, and S. L. Keller. 2004. Liquid domains in vesicles investigated by NMR and fluorescence microscopy. Biophys. J. 86:2910-2922.
76. Viovy, J. L., W. M. Gelbart, and A. Ben-Shaul. 1987. Scaling properties of chain interactions in amphiphilic aggregates. J. Chem. Phys. 87:4114-4125.
77. Weikl, T. R. 2001. Fluctuation-induced aggregation of rigid membrane inclusions. Europhys. Lett. 54:547-553.
78. Weikl, T. R. 2002. Dynamic phase separation of fluid membranes with rigid inclusions. Phys. Rev. E. 66:061915.
79. Weikl, T. R., M. M. Kozlov, and W. Helfrich. 1998. Interaction of conical membrane inclusions: Effect of lateral tension. Physical Review E. 57:6988-6995.
80. Wiggins, P., and R. Phillips. 2004. Analytic models for mechanotransduction: gating a mechanosensitive channel. Proc. Natl. Acad. Sci. USA. 101:4071-4076.
81. Worthman, L. A. D., K. Nag, P. J. Davis, and K. M. W. Keough. 1997. Cholesterol in condensed and fluid phosphatidylcholine monolayers studied by epifluorescence microscopy. Biophys. J. 72:2569-2580.
82. Yeagle, P. L. 1988. Biology of Cholesterol. CRC Press, Boca Raton, FL.