Association analysis of monocyte chemotactic protein-3 (MCP3) polymorphisms with asthmatic phenotypes

Journal of Biochemistry and Molecular Biology

Volumn 38, Issue 1, 2005, Pages 77-81

  Byung, Lae Park ^a   Lyoung, Hyo Kim ^a   Yoo, Hyun Choi ^a   Hyun, Sub Cheong ^a   Park, Hae Sim ^b   Hong, Soo Jong ^b   Byoung, Whui Choi ^b   Lee, June Hyuk ^b   Uh, Soo Taek ^b   Park, Choon Sik ^b   Hyoung, Doo Shin ^a  

^a SNP Genetics Inc   (South Korea)

^b Soonchunhyang University College of Medicine   (South Korea)

Author keywords

Allergic disease; Asthma; MCP3; Single nucleotide polymorphism

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN E; MONOCYTE CHEMOTACTIC PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 3;

ADOLESCENT; ADULT; AGED; ARTICLE; ASTHMA; BLOOD; CASE CONTROL STUDY; CHILD; CHROMOSOME 17; COMPARATIVE STUDY; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENETIC VARIABILITY; GENETICS; HUMAN; MALE; MIDDLE AGED; PHENOTYPE; SINGLE NUCLEOTIDE POLYMORPHISM; SKIN TEST;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ASTHMA; CASE-CONTROL STUDIES; CHILD; CHROMOSOMES, HUMAN, PAIR 17; CYTOKINES; FEMALE; HUMANS; IMMUNOGLOBULIN E; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; MONOCYTE CHEMOATTRACTANT PROTEINS; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; SKIN TESTS; VARIATION (GENETICS);

EID: 21244442722     PISSN: 12258687     EISSN: 12258687     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Baggiolini, M., Dewald, B. and Moser, B. (1994) Interleukin-8 and related chemotactic cytokines - CXC and CC chemokines. Adv. Immunol. 55, 97-179.
2. Ben-Baruch, A., Xu, L., Young, P. R., Bengali, K., Oppenheim, J. J. and Wang, J. M. (1995) Monocyte chemotactic protein-3 (MCP3) interacts with multiple leukocyte receptors. C-C CKR1, a receptor for macrophage inflammatory protein-1 alpha/Rantes, is also a functional receptor for MCP3. J. Biol. Chem. 270, 22123-22128.
3. Hedrick, P. and Kumar, S. (2001) Mutation and linkage disequilibrium in human mtDNA. Eur. J. Hum. Genet. 9, 969-972.
4. Hedrick, P. W. (1987) Gametic disequilibrium measures: proceed with caution. Genetics 117, 331-341.
5. Humbert, M., Ying, S., Corrigan, C., Menz, G., Barkans, J., Pfister, R., Meng, Q., Van Damme, J., Opdenakker, G., Durham, S. R. and Kay, A. B. (1997) Bronchial mucosal expression of the genes encoding chemokines RANTES and MCP-3 in symptomatic atopic and nonatopic asthmatics: relationship to the eosinophil-active cytokines interleukin (IL)-5, granulocyte macrophagecolony- stimulating factor, and IL-3. Am. J. Respir. Cell Mol. Biol. 16, 1-8.
6. Kim, M. H., Kim, H. J., Choi, J. Y. and Nahm, D. S. (2003) Transforming growth factor-beta3 gene SfaN1 polymorphism in Korean nonsyndromic cleft lip and palate patients. J. Biochem. Mol. Biol. 36, 533-537.
7. Livak, K. J. (1999) Allelic discrimination using fluorogenic probes and the 5′ nuclease assay. Genet. Anal. 14, 143-149.
8. Powell, N., Humbert, M., Durham, S. R., Assoufi, B., Kay, A. B. and Corrigan, C. J. (1996) Increased expression of mRNA encoding RANTES and MCP-3 in the bronchial mucosa in atopic asthma. Eur. Respir. J. 9, 2454-2460.
9. Rojas-Ramos, E., Avalos, A. F., Perez-Fernandez, L., Cuevas-Schacht, F., Valencia-Maqueda, E. and Teran, L. M. (2003) Role of the chemokines RANTES, monocyte chemotactic proteins-3 and -4, and eotaxins-1 and -2 in childhood asthma. Eur. Respir. J. 22, 310-316.
10. Stafford, S., Li, H., Forsythe, P. A., Ryan, M., Bravo, R. and Alam, R. (1997) Monocyte chemotactic protein-3 (MCP-3)/fibroblastinduced cytokine (FIC) in eosinophilic inflammation of the airways and the inhibitory effects of an anti-MCP-3/FIC antibody. J. Immunol. 158, 4953-4960.
11. Stephens, M., Smith, N. J. and Donnelly, P. (2001) A new statistical method for haplotype reconstruction from population data. Am. J. Hum. Genet. 68, 978-989.
12. Xu, L. L., McVicar, D. W., Ben-Baruch, A., Kuhns, D. B., Johnston, J., Oppenheim, J. J. and Wang, J. M. (1995) Monocyte chemotactic protein-3 (MCP3) interacts with multiple leukocyte receptors: binding and signaling of MCP3 through shared as well as unique receptors on monocytes and neutrophils. Eur. J. Immunol. 25, 2612-2617.
13. Ying, S., Meng, Q., Zeibecoglou, K., Robinson, D. S., Macfarlane, A., Humbert, M. and Kay, A. B. (1999) Eosinophil chemotactic chemokines (eotaxin, eotaxin-2, RANTES, monocyte chemoattractant protein-3 (MCP-3), and MCP-4), and C-C chemokine receptor 3 expression in bronchial biopsies from atopic and nonatopic (Intrinsic) asthmatics. J. Immunol. 163, 6321-6329.
14. + polymerase. J. Biochem. Mol. Biol. 36, 525-528.