P2 pyridine N-oxide thrombin inhibitors: A novel peptidomimetic scaffold

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 11, 2005, Pages 2771-2775

  Nantermet, Philippe G ^a   Burgey, Christopher S ^a   Robinson, Kyle A ^a   Pellicore, Janetta M ^a   Newton, Christina L ^a   Deng, James Z ^a   Selnick, Harold G ^a   Lewis, S Dale ^a   Lucas, Bobby J ^a   Krueger, Julie A ^a   Miller Stein, Cynthia ^a   White, Rebecca B ^a   Wong, Bradley ^a   McMasters, Daniel R ^a   Wallace, Audrey A ^a   Lynch Jr , Joseph J ^a   Yan, Youwei ^a   Chen, Zhongguo ^a   Kuo, Lawrence ^a   Gardell, Stephen J ^a   Shafer, Jules A ^a   Vacca, Joseph P ^a   Lyle, Terry A ^a   more..

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Peptidomimetic; Thrombin

Indexed keywords

2 AMINOPYRIDINE DERIVATIVE; 2 AMINOPYRIDINE N OXIDE THROMBIN INHIBITOR; PEPTIDOMIMETIC AGENT; THROMBIN INHIBITOR; UNCLASSIFIED DRUG; ANTITHROMBIN; PYRIMIDINE DERIVATIVE;

AEROBIC METABOLISM; ARTICLE; CONTROLLED STUDY; DOG; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG SYNTHESIS; HYDROGEN BOND; NONHUMAN; CHEMICAL STRUCTURE; CHEMISTRY; MOLECULAR MIMICRY;

CANIS FAMILIARIS;

ANTITHROMBINS; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR MIMICRY; PYRIMIDINES;

EID: 21144453843     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.03.110     Document Type: Article

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20. 3 pyridyl