Association of 14-3-3 ε gene haplotype with completed suicide in Japanese

Journal of Human Genetics

Volumn 50, Issue 4, 2005, Pages 210-216

  Yanagi, Masaya ^a   Shirakawa, Osamu ^a   Kitamura, Noboru ^b   Okamura, Kenji ^a   Sakurai, Kaoru ^a   Nishiguchi, Naoki ^a   Hashimoto, Takeshi ^a   Nushida, Hideyuki ^a   Ueno, Yasuhiro ^a   Kanbe, Daiji ^c   Kawamura, Meiko ^c   Araki, Kazuaki ^c   Nawa, Hiroyuki ^c   Maeda, Kiyoshi ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KOBE CITY MEDICAL CENTER GENERAL HOSPITAL   (Japan)

^c NIIGATA UNIVERSITY   (Japan)

Author keywords

14 3 3 (epsilon); Completed suicide victims; Immunoreactivity; Microarray; Postmortem brain; Single nucleotide polymorphism

Indexed keywords

ADULT; AGED; ALLELE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DNA MICROARRAY; FEMALE; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC SUSCEPTIBILITY; GENOME ANALYSIS; HAPLOTYPE; HEREDITY; HUMAN; JAPAN; MALE; NERVOUS SYSTEM DEVELOPMENT; NUCLEOTIDE SEQUENCE; PATHOGENESIS; SINGLE NUCLEOTIDE POLYMORPHISM; SUICIDE; UPREGULATION; WESTERN BLOTTING;

14-3-3 PROTEINS; ADULT; AGED; FEMALE; GENE EXPRESSION PROFILING; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HUMANS; JAPAN; MALE; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; SUICIDE;

EID: 21044457788     PISSN: 14345161     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10038-005-0241-0     Document Type: Article

References (38)

1. Anguelova M, Benkelfat C, Turecki GA (2003) Systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: II. Suicidal behavior. Mol Psychiatry 8:646-653
2. Asberg M (1997) Neurotransmitters and suicidal behavior. The evidence from cerebrospinal fluid studies. Ann NY Acad Sci 29:158-181
3. Asberg M, Traskman L, Thoren P (1976) 5-HIAA in the cerebrospinal fluid. A biochemical suicide predictor? Arch Gen Psychiatry 33:1193-1197
4. Baldessarini RJ, Tondo L, Hennen J (2001) Treating the suicidal patient with bipolar disorder. Reducing suicide risk with lithium. Ann NY Acad Sci 932:24-38; discussion 39-43
5. Bellivier F, Chaste P, Malafosse A (2004) Association between the TPH gene A218C polymorphism and suicidal behavior: a meta-analysis. Am J Med Genet 1 124B:87-91
6. Berg D, Holzmann C, Riess O (2003) 14-3-3 proteins in the nervous system. Nat Rev Neurosci 4:752-762
7. Bernier PJ, Bedard A, Vinet J, Levesque M, Parent A (2002) Newly generated neurons in the amygdala and adjoining cortex of adult primates. Proc Natl Acad Sci USA 20 99:11464-11469
8. Brezun JM, Daszuta A (1999) Depletion in serotonin decreases neurogenesis in the dentate gyrus and the subventricular zone of adult rats. Neuroscience 89:999-1002
9. Cheetham SC, Crompton MR, Czudek C, Horton RW, Katona CL, Reynolds GP (1989) Serotonin concentrations and turn-over in brains of depressed suicides. Brain Res 20 502:332-340
10. Chen G, Rajkowska G, Du F, Seraji-Bozorgzad N, Manji HK (2000) Enhancement of hippocampal neurogenesis by lithium. J Neurochem 75:1729-1734
11. Chen HK, Fernandez-Funez P, Acevedo SF, Lam YC, Kaytor MD, Fernandez MH, Aitken A, Skoulakis EM, Orr HT, Botas J, Zoghbi HY (2003) Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1. Cell 16 113:457-468
12. Gaspar P, Cases O, Maroteaux L (2003) The developmental role of serotonin: news from mouse molecular genetics. Nat Rev Neurosci 4:1002-1012
13. Goodwin FK, Fireman B, Simon GE, Hunkeler EM, Lee J, Revicki D (2003) Suicide risk in bipolar disorder during treatment with lithium and divalproex. JAMA 17 290:1467-1473
14. Gould E (1999) Serotonin and hippocampal neurogenesis. Neuropsychopharmacology 21(2 Suppl):46S-51S
15. Gould E, McEwen BS, Tanapat P, Galea LA, Fuchs E (1997) Neurogenesis in the dentate gyrus of the adult tree shrew is regulated by psychosocial stress and NMDA receptor activation. Neurosci 1 17:2492-2498
16. Gould E, Tanapat P, McEwen BS, Flugge G, Fuchs E (1998) Proliferation of granule cell precursors in the dentate gyrus of adult monkeys is diminished by stress. Proc Natl Acad Sci USA 17 95:3168-3171
17. Haga H, Yamada R, Ohnishi Y, Nakamura Y, Tanaka T (2002) Gene-based SNP discovery as part of the Japanese millennium genome project: identification of 190,562 genetic variations in the human genome. Single-nucleotide polymorphism. J Hum Genet 47:605-610
18. Halim ND, Weickert CS, McClintock BW, Weinberger DR, Lipska BK (2004) Effects of chronic haloperidol and clozapine treatment on neurogenesis in the adult rat hippocampus. Neuropsychopharmacology 29:1063-1069
19. Hirakawa M, Tanaka T, Hashimoto Y, Kuroda M, Takagi T, Nakamura Y (2002) JSNP: a database of common gene variations in the Japanese population. Nucleic Acids Res 1 30:158-162
20. Hrdina PD, Demeter E, Vu TB, Sotonyi P, Palkovits M (1993) 5-HT uptake sites and 5-HT2 receptors in brain of antidepressant-free suicide victims/depressives: increase in 5-HT2 sites in cortex and amygdala. Brain Res 18 614(1, 2):37-44
21. Ichimura T, Uchiyama J, Kunihiro O, Ito M, Horigome T, Omata S, Shinkai F, Kaji H, Isobe T (1995) Identification of the site of interaction of the 14-3-3 protein with phosphorylated tryptophan hydroxylase. J Biol Chem 1 270:28515-28518
22. Iwamoto K, Kakiuchi C, Bundo M, Ikeda K, Kato T (2004) Molecular characterization of bipolar disorder by comparing gene expression profiles of postmortem brains of major mental disorders. Mol Psychiatry 9:406-416
23. Jacobs BL, Praag H, Gage FH (2000) Adult brain neurogenesis and psychiatry: a novel theory of depression. Mol Psychiatry 5:262-269
24. Jia Y, Yu X, Zhang B, Yuan Y, Xu Q, Shen Y, Shen Y (2004) An association study between polymorphisms in three genes of 14-3-3 (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein) family and paranoid schizophrenia in northern Chinese population. Eur Psychiatry 19:377-379
25. Kim JS, Chang MY, Yu IT, Kim JH, Lee SH, Lee YS, Son H (2004) Lithium selectively increases neuronal differentiation of hippocampal neural progenitor cells both in vitro and in vivo. J Neurochem 89:324-336
26. Malone KM, Corbitt EM, Li S, Mann JJ (1996) Prolactin response to fenfluramine and suicide attempt lethality in major depression. Br J Psychiatry 168:324-329
27. Mann JJ, Oquendo M, Underwood MD, Arango V (1999) The neurobiology of suicide risk: a review for the clinician. J Clin Psychiatry 60(Suppl) 2:7-11; discussion 18-20, 113-116
28. Meltzer HY (2001) Treatment of suicidality in schizophrenia. Ann NY Acad Sci 932:44-58; discussion 58-60
29. Meltzer HY, Alphs L, Green AI, Altamura AC, Anand R, Bertoldi A, Bourgeois M, Chouinard G, Islam MZ, Kane J, Krishnan R, Lindenmayer JP, Potkin S (2003) International suicide prevention trial study group. Clozapine treatment for suicidality in schizophrenia: international suicide prevention trial (InterSePT). Arch Gen Psychiatry 60:82-91
30. Muller-Oerlinghausen B, Berghofer A, Bauer M (2002) Bipolar disorder. Lancet 19 359(9302):241-247
31. Ono H, Shirakawa O, Kitamura N, Hashimoto T, Nishiguchi N, Nishimura A, Nushida H, Ueno Y, Maeda K (2002) Tryptophan hydroxylase immunoreactivity is altered by the genetic variation in postmortem brain samples of both suicide victims and controls. Mol Psychiatry 7:1127-1132
32. Roy A, Segal NL, Centerwall BS, Robinette CD (1991) Suicide in twins. Arch Gen Psychiatry 48:29-32
33. Tanapat P, Galea LA, Gould E (1998) Stress inhibits the proliferation of granule cell precursors in the developing dentate gyrus. Int J Dev Neurosci 16:235-239
34. Toyo-oka K, Muratake T, Tanaka T, Igarashi S, Watanabe H, Takeuchi H, Hayashi S, Maeda M, Takahashi M, Tsuji S, Kumanishi T, Takahashi Y (1999) 14-3-3 protein eta chain gene (YWHAH) polymorphism and its genetic association with schizophrenia. Am J Med Genet 16 88:164-167
35. Toyo-oka K, Shionoya A, Gambello MJ, Cardoso C, Leventer R, Ward HL, Ayala R, Tsai LH, Dobyns W, Ledbetter D, Hirotsune S, Wynshaw-Boris A (2003) 14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome. Nat Genet 34:274-285
36. Wender PH, Kety SS, Rosenthal D, Schulsinger F, Ortmann J, Lunde I (1986) Psychiatric disorders in the biological and adoptive families of adopted individuals with affective disorders. Arch Gen Psychiatry 43:923-929
37. Wong AH, Macciardi F, Klempan T, Kawczynski W, Barr CL, Lakatoo S, Wong M, Buckle C, Trakalo J, Boffa E, Oak J, Azevedo MH, Dourado A, Coelho I, Macedo A, Vicente A, Valente J, Ferreira CP, Pato MT, Pato CN, Kennedy JL, Van Tol HH (2003) Identification of candidate genes for psychosis in rat models, and possible association between schizophrenia and the 14-3-3 eta gene. Mol Psychiatry 8:156-166
38. Young LT, Bezchlibnyk YB, Chen B, Wang JF, MacQueen GM (2004) Amygdala cyclic adenosine monophosphate response element binding protein phosphorylation in patients with mood disorders: effects of diagnosis, suicide, and drug treatment. Biol Psychiatry 15 55:570-577