Increased CD40 ligand in patients with acute anterior uveitis

Acta Ophthalmologica Scandinavica

Volumn 83, Issue 3, 2005, Pages 370-373

  Øgard, Carsten ^a,b   Sørensen, Torben L ^a   Krogh, Erik ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Anterior uveitis; Autoimmunity; CD 154; CD40 ligand; Cytokine; Optic neuritis

Indexed keywords

CD19 ANTIGEN; CD4 ANTIGEN; CD40 LIGAND; CD8 ANTIGEN;

ACUTE DISEASE; ADULT; ARTICLE; B LYMPHOCYTE; CELL ISOLATION; CLINICAL ARTICLE; CLINICAL EXAMINATION; CONTROLLED STUDY; EX VIVO STUDY; FEMALE; FLOW CYTOMETRY; HUMAN; IMMUNOPATHOGENESIS; LYMPHOCYTE SUBPOPULATION; MALE; OPTIC NERVE DISEASE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SYMPTOMATOLOGY; T LYMPHOCYTE ACTIVATION; UVEITIS;

ACUTE DISEASE; ADULT; AUTOIMMUNITY; B-LYMPHOCYTES; CD4-POSITIVE T-LYMPHOCYTES; CD40 LIGAND; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; FLOW CYTOMETRY; HUMANS; LYMPHOCYTE ACTIVATION; MALE; MIDDLE AGED; UVEITIS, ANTERIOR;

EID: 21044450105     PISSN: 13953907     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0420.2005.00421.x     Document Type: Article

References (36)

1. Balashov KE, Smith DR, Khoury SJ, Hafler DA & Weiner HL (1997): Increased interleukin-12 production in progressive multiple sclerosis: induction by activated CD4+ T-cells via CD40 ligand. Proc Natl Acad Sci 94: 599-603.
2. Becker MD, Adamus G, Davey MP & Rosenbaum JT (2000): The role of T-cells in autoimmune uveitis. Ocul Immunol Inflamm 8: 93-100.
3. Becker MD & Rosenbaum JT (2000): Current and future trends in the use of immunosuppressive agents in patients with uveitis. Curr Opin Ophthalmol 11: 472-477.
4. Bloch-Michel E & Nussenblatt RB (1987): International Uveitis Study Group recommendations for the evaluation of intraocular inflammatory disease. Am J Ophthalmol 103: 234-235.
5. Calder VL, Shaer B, Muhaya M, McLauchlan M, Pearson RV, Jolly G, Towler HM & Lightman S (1999): Increased CD4+ expression and decreased IL-10 in the anterior chamber in idiopathic uveitis. Invest Ophthalmol Vis Sci 40: 2019-2024.
6. Casamayor-Palleja M, Khan M & MacLennan ICM (1995): A subset of CD4+ memory T-cells contains preformed CD40 ligand that is rapidly but transiently expressed on their surface after activation through the T-cell receptor complex. J Exp Med 181: 1293-1301.
7. Castle BE, Kishimoto K, Stearns C, Brown ML & Kehry MR (1993): Regulation of expression of the ligand for CD40 on T helper lymphocytes. J Immunol 151: 1777-1788.
8. Dick AD, Siepmann K, Dees C, Duncan L, Broderick C, Liversidge J & Forrester JV (1999): Fas-Fas ligand-mediated apoptosis within aqueous during idiopathic acute anterior uveitis. Invest Ophthalmol Vis Sci 40: 2258-2267.
9. Durie FH, Fava RA, Foy TM, Aruffo A, Ledbetter JA & Noelle RJ (1993): Prevention of collagen induced arthritis with an antibody to gp39, the ligand for CD40. Science 261: 1328-1330.
10. Fanslow WC, Srinivasan S, Paxton R, Gibson MG, Spriggs MK & Armitage RJ (1994): Structural characteristics of CD40 ligand that determine biological function. Seminars Immunol 6: 267-278.
11. Foxman EF, Zhang M, Hurst SD, Muchamuel T, Shen D, Wawrousek EF, Chan C-C & Gery I (2002): Inflammatory mediators in uveitis: differential induction of cytokines and chemokines in Th1- versus Th2-mediated ocular inflammation. J Immnunol 168: 2483-2492.
12. Grewal IS & Flavell RA (1998): CD40 and CD154 in cell-mediated immunity. Annu Rev Immunol 16: 111-135.
13. Hayashi S, Guex-Crosier Y, Delvaux A, Velu T & Roberge FG (1996): Interleukin-10 inhibits inflammatory cells infiltration in endotoxin-induced uveitis. Graefes Arch Clin Exp Ophthalmol 234: 633-636.
14. Holder MJ, Wang H & Milner AE et al. (1993): Suppression of apoptosis in normal and neoplastic human B lymphocytes by CD40 ligand is independent of Bcl-2 induction. Eur J Immunol 23: 2368-2371.
15. Hollenbaugh D, Grosmaire LS & Kullas CD et al. (1992): The human T-cell antigen gp 39, a member of the TNF gene family, is a ligand for the CD40 receptor: expression of a soluble form of gp 39 with B-cell co-stimulatory activity. Eur Mol Biol Organ J 11: 4313-4321.
16. Howard LM, Miga AJ, Vanderlugt CL, Dal Canto MC, Laman JD, Noelle RJ & Miller SD (1999): Mechanisms of immunotherapeutic intervention by anti-CD40L (CD154) antibody in an animal model of multiple sclerosis. J Clin Invest 103: 281-290.
17. Jung T, Schauer U, Heusser C, Neumann C & Rieger C (1993): Detection of intracellular cytokines by flow cytometry. J Immunol Meth 159: 197-207.
18. Kennedy MK, Picha KS, Fanslow WC, Grabstein KH, Alderson MR, Clifford KN, Chin WA & Mohler KM (1996): CD40/CD40 ligand interactions are required for T-cell-dependent production of interleukin-12 by mouse macrophages. Eur J Immunol 26: 370-378.
19. Kijlstra A (1997): Cytokines: their role in uveal disease. Eye 11: 200-205.
20. Klitgaard TLS, Øgard C & Krogh E (2004): Chemokine receptors and early activation markers in acute anterior uveitis. Acta Ophthalmol Scand 82: 179-183.
21. La Heij E, Kuijpers RWAM, Baarsma SG, Kijlstra A, van der Weiden M & Mooy CM (1998): Adhesion molecules in iris biopsy specimens from patients with uveitis. Br J Ophthalmol 82: 432-437.
22. Lacomba MS, Martin CM, Galera JMG, Vidal MAG, Estévez EC, Chamond RR & Omar M (2001): Aqueous humour and serum tumour necrosis factor-α in clinical uveitis. Ophthalmic Res 33: 251-255.
23. Lane P, Traunecker A, Hubele A, Inui S, Lanzavecchia A & Gray D (1992): Activated human T-cells express a ligand for the human B-cell-associated antigen CD40 which participates in T-cell-dependent activation of B lymphocytes. Eur J Immunol 22: 2573-2578.
24. Ludewig B, Graf D, Gelderblom HR, Becker Y, Kroczek RA & Pauli G (1995): Spontaneous apoptosis of dendritic cells is efficiently inhibited by TRAP (CD40-ligand) and TNF-α, but strongly enhanced by interleukin-10. Eur J Immunol 25: 1943-1950.
25. MacDonald KPA, Nishioka Y, Lipsky PE & Thomas R (1997): Functional CD40 ligand is expressed by T-cells in rheumatoid arthritis. J Clin Invest 100: 2404-2414.
26. Muhaya M, Calder V, Towler HM, Shaer B, McLauchlan M & Lightman S (1998): Characterization of T-cells and cytokines in the aqueous humour (AH) in patients with Fuchs' heterochromic cyclitis (FHC) and idiopathic anterior uveitis (IAU). Clin Exp Immunol 111: 123-128.
27. Noelle RJ, Ledbetter JA & Aruffo JA (1992): CD40 and its ligand, an essential ligand-receptor pair for thymus-dependent B-cell activation. Immunol Today 13: 431-433.
28. Qian Y, Boisgerault F, Benichou G & Dana MR (2001): Blockade of CD40 CD154 co-stimulatory pathway promotes survival of allogenic corneal transplants. Invest Ophthalmol Vis Sci 42: 987-994.
29. Streilein JW, Ksander BR & Taylor AW (1997a): Immune deviation in relation to ocular immune privilege. J Immunol 158: 3557-3560.
30. Streilein JW, Takeuchi M & Taylor AW (1997b): Immune privilege, T-cell tolerance and tissue-restricted autoimmunity. Hum Immunol 52: 138-143.
31. Stüber E, Strober W & Neurath M (1996): Blocking the CD40L-CD40 interaction in vivo specifically prevents the priming of T helper 1 cells through the inhibition of interleukin-12 secretion. J Exp Med 183: 693-698.
32. de Vos AF, Dick AD, Klooster J, Broersma L, McMenamin PG & Kijlstra A (2000): Analysis of the cellular infiltrate in the iris during experimental autoimmune encephalomyelitis. Invest Ophthalmol Vis Sci 41: 3001-3010.
33. Wakefield D, Cuello C, Di Girolamo N & Lloyd A (1999): The role of cytokines and chemokines in uveitis. Dev Ophthalmol 31: 53-66.
34. Wakefield D, McCluskey P & Palladinetti P (1992): Distribution of lymphocytes and cell adhesion molecules in iris biopsy specimens from patients with uveitis. Arch Ophthalmol 110: 121-125.
35. Woon M-D, Kaplan HJ & Bora NS (1998): Kinetics of cytokine production in experimental autoimmune anterior uveitis (EAAU). Curr Eye Res 17: 955-961.
36. Yellin MJ, Sippel K & Inghirami G et al. (1994): CD40 molecules induce down-modulation and endocytosis of T-cell surface T-cell B-cell activating molecule/CD40-L. J Immunol 152: 598-608.