CIK cells from patients with HCC possess strong cytotoxicity to multidrug-resistant cell line Bel-7402/R

World Journal of Gastroenterology

Volumn 11, Issue 22, 2005, Pages 3339-3345

  Zhang, You Shun ^a   Yuan, Fang Jun ^a   Jia, Guo Feng ^a   Zhang, Ji Fa ^a   Hu, Li Yi ^a   Huang, Ling ^a   Wang, Ju ^a   Dai, Zong Qing ^a  

^a Institute of Liver Surgery   (China)

Author keywords

Cytokine induced killer; Cytotoxicity; Hepatocellular carcinoma; Multidrug resistance; P glycoprotein

Indexed keywords

CD3 ANTIGEN; CD56 ANTIGEN; DOXORUBICIN; MESSENGER RNA; RECOMBINANT GAMMA INTERFERON; RECOMBINANT INTERLEUKIN 1; RECOMBINANT INTERLEUKIN 2;

ADOPTIVE IMMUNOTHERAPY; ADULT; ARTICLE; CANCER CELL CULTURE; CELL MEDIATED CYTOTOXICITY; CELL PROLIFERATION; CELL SURVIVAL; CLINICAL ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; LIVER CELL CARCINOMA; MALE; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 21044448985     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v11.i22.3339     Document Type: Article

References (26)

1. Zhang YS, Dai ZQ. Advances in Hepatoma Biotherapy Research. Zhongguo Xiandai Putong Waike Jinzhan 2001; 4: 193-198
2. Kline NE. Promoting patient safety through the development of a pediatric chemotherapy and biotherapy provider program. J Pediatr Oncol Nurs 2004; 21: 65-66
3. Tan GH, Wei YQ, Tian L, Zhao X, Yang L, Li J, He QM, Wu Y, Wen YJ, Yi T, Ding ZY, Kan B, Mao YQ, Deng HX, Li HL, Zhou CH, Fu CH, Xiao F, Zhang XW. Active immunotherapy of tumors with a recombinant xenogeneic endoglin as a model antigen. Eur J Immunol 2004; 34: 2012-2021
4. Rice AM, Jones KL, Hart DN. DC preparations for therapy. Cytotherapy 2004; 6: 99-104
5. Hongeng S, Petvises S, Worapongpaiboon S, Rerkamnuaychoke B, Pakakasama S, Jootar S. Generation of CD3+ CD56+ cytokine-induced killer cells and their in vitro cytotoxicity against pediatric cancer cells. Int J Hematol 2003; 77: 175-179
6. Bonin S, Pascolo L, Croce LS, Stanta G, Tiribelli C. Gene expression of ABC proteins in hepatocellular carcinoma, perineoplastic tissue, and liver diseases. Mol Med 2002; 8: 318-325
7. van Brussel JP, van Steenbrugge GJ, Romijn JC, Schroder FH, Mickisch GH. Chemosensitivity of prostate cancer cell lines and expression of multidrug resistance-related proteins. Eur J Cancer 1999; 35: 664-671
8. Warmann S, Gohring G, Teichmann B, Geerlings H, Pietsch T, Fuchs J. P-glycoprotein modulation improves in vitro chemosensitivity in malignant pediatric liver tumors. Anticancer Res 2003; 23: 4607-4611
9. Schmidt-Wolf IG, Negrin RS, Kiem HP, Blume KG, Weissmen IL. Use of a SCID mouse/human lymphoma model to evaluate cytokine-induced killer cells with potent antitumor cell activity. J Exp Med 1991; 174: 139-149
10. Schmidt-Wolf IG, Negrin RS, Schmidt-Wolf IG. Activated T cells and cytokine-induced CD3+CD56+ killer cells. Ann Hematol 1997; 74: 51-56
11. Schmidt-Wolf IG, Lefterova P, Mehta BA, Fernandez LP, Huhn D, Blume KG, Weissman IL, Negrin RS. Phenotypic characterization and identification of effector cells involved in tumor cell recognition of cytokine-induced killer cells. Exp Hematol 1993; 21: 1673-1679
12. Kaneko T, Fusauch Y, Kakui Y, Okumura K, Mizoguchi H, Oshimi K. Cytotoxicity of cytokine-induced killer cells coated with bispecific antibody against acute myeloid leukemia cells. Leuk Lymphoma 1994; 14: 219-229
13. Mehta BA, Schmidt-Wolf IG, Weissman IL, Negrin RS. Two pathways of exocytosis of cytoplasmic granule contents and target cell killing by cytokine-induced CD3+CD56+ killer cells. Blood 1995; 86: 3493-3499
14. Zhang YS, Huang L, Yuan FJ, Wang B, Dai ZQ. Research on effects of tumor vaccine to mouse hepatocellular carcinoma. Yunyang Yixueyuan Xuebao 2002; 21: 8-12
15. Shapiro AB, Ling V. The mechanism of ATP-dependent multidrug transport by P-glycoprotein. Acta Physiol Scand Suppl 1998; 643: 227-234
16. Zhang YS, Yao L, Huang L, Wang B, Dai ZQ. Observation on cytotoxicity of CD3AK. Yunyang Yixueyuan Xuebao 1999; 18: 200-201
17. Nakajima A, Yamamoto Y, Taura K, Hata K, Fukumoto M, Uchinami H, Yonezawa K, Yamaoka Y. Beneficial effect of cepharanthine on overcoming drug-resistance of hepatocellular carcinoma. Int J Oncol 2004; 24: 635-645
18. He L, Liu GQ. Effects of various principles from Chinese herbal medicine on rhodamine123 accumulation in brain capillary endothelial cells. Acta Pharmacol Sin 2002; 23: 591-596
19. Chu TM, Lin TH, Kawinski E. Detection of soluble P-glycoprotein in culture media and extracellular fluids. Biochem Biophys Res Commun 1994; 203: 506-512
20. Schmidt-Wolf IG, Finke S, Trojaneck B, Denkena A, Lefterova P, Schwella N, Heuft HG, Prange G, Korte M, Takeya M, Dorbic T, Neubauer A, Wittig B, Huhn D. Phase I clinical study applying autologous immunological effector cells transfected with the interleukin-2 gene in patients with metastatic renal cancer, colorectal cancer and lymphoma. Br J Cancer 1999; 81: 1009-1016
21. Alvarnas JC, Linn YC, Hope EG, Negrin RS. Expansion of cytotoxic CD3+ CD56+ cells from peripheral blood progenitor cells of patients undergoing autologous hematopoietic cell transplantation. Biol Blood Marrow Transplant 2001; 7: 216-222
22. Marten A, Ziske C, Schottker B, Renoth S, Weineck S, Buttgereit P, Schakowski F, von Rucker A, Sauerbruch T, Schmidt-Wolf IG. Interactions between dendritic cells and cytokine-induced killer cells lead to an activation of both populations. J Immunother 2001; 24: 502-510
23. Holness CL, Simmons DL. Molecular cloning of CD68, a human macrophage marker related to lysosomal glycoproteins. Blood 1993; 81: 1607-1613
24. Gold JE, Zachary DT, Osband ME. Adoptive transfer of ex vivo-activated memory T-cell subsets with cyclophosphamide provides effective tumor-specific chemoimmunotherapy of advanced metastatic murine melanoma and carcinoma. Int J Cancer 1995; 61: 580-586
25. Schmidt-Wolf IG, Lefterova P, Johnston V, Scheffold C, Csipai M, Mehta BA, Tsuruo T, Huhn D, Negrin RS. Sensitivity of multidrug-resistant tumor cell lines to immunologic effector cells. Cell Immunol 1996; 169: 85-90
26. Shao GZ, Zhou RL, Zhang QY, Zhang Y, Liu ff, Rui JA, Wei X, Ye DX. Molecular cloning and characterization of LAPTM4B, a novel gene upregulated in hepatocellular carcinoma. Oncogene 2003; 22: 5060-5069