Angiotensin depolarizes parvocellular neurons in paraventricular nucleus through modulation of putative nonselective cationic and potassium conductances

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 289, Issue 1 58-1, 2005, Pages

  Latchford, Kevin J ^a   Ferguson, Alastair V ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

Electrophysiology; Ion channels; Neuroendocrine regulation

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; CATION; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; ION CHANNEL; LOSARTAN; NEUROTRANSMITTER; POTASSIUM; TETRODOTOXIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE DEPOLARIZATION; ELECTROPHYSIOLOGY; EXCITATORY POSTSYNAPTIC POTENTIAL; HORMONE RELEASE; HYPOPHYSIS; HYPOTHALAMUS; NERVE CONDUCTION; NERVE EXCITABILITY; NEUROENDOCRINE SYSTEM; NEUROMODULATION; NEUROSECRETION; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT; THALAMUS MIDLINE NUCLEUS; VOLTAGE CLAMP;

ANGIOTENSIN II; ANIMALS; CATIONS; ELECTROPHYSIOLOGY; ION CHANNELS; LOSARTAN; MALE; NEURONS; NEUROSECRETORY SYSTEMS; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; RATS; RATS, SPRAGUE-DAWLEY; TETRODOTOXIN;

EID: 21044441057     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.00549.2004     Document Type: Article

References (49)

1. Aguilera G, Young WS, Kiss A, and Bathia A. Direct regulation of hypothalamic corticotropin-releasing-hormone neurons by angiotensin II. Neuroendocrinology 61: 437-444, 1995.
2. Bai D and Renaud LP. ANG II AT1 receptors induce depolarization and inward current in rat median preoptic neurons in vitro. Am J Physiol Regul Integr Comp Physiol 275: R632-R639, 1998.
3. Bains JS and Ferguson AV: Nitric oxide regulates NMDA driven GABAergic inputs to type I neurons of the rat paraventricular nucleus. J Physiol 499: 733-746, 1997.
4. Barnes KL, DeWeese DM, and Andresen MC. Angiotensin potentiates excitatory sensory synaptic transmission to medial solitary tract nucleus neurons. Am J Physiol Regul Integr Comp Physiol 284: R1340-R1353, 2003.
5. Cato MJ and Toney GM. Angiotensin II excites paraventricular nucleus neurons that innervate the rostral ventrolateral medulla: an in vitro patch-clamp study in brain slices. J Neurophysiol 93: 403-413, 2005.
6. Cui LN, Coderre E, and Renaud LP. Glutamate and GABA mediate suprachiasmatic nucleus inputs to spinal-projecting paraventricular neurons. Am J Physiol Regul Integr Comp Physiol 281: R1283-R1289, 2001.
7. Culman J, Hohle S, Qadri F, Edling O, Blume A, Lebrun C, and Unger T. Angiotensin as neuromodulator/neurotransmitter in central control of body fluid and electrolyte homeostasis. Clin Exp Hypertens 17: 281-293, 1995.
8. h in neurones of the rat paraventricular nucleus. Neurosci Lett 330: 53-56, 2002.
9. Ferguson AV and Wall KM. Central actions of angiotensin in cardiovascular control: multiple roles for a single peptide. Can J Physiol Pharmacol 70: 779-785, 1992.
10. Ferguson AV, Washburn DL, and Latchford KJ. Hormonal and neurotransmitter roles for angiotensin in the regulation of central autonomic function. Exp Biol Med (Maywood) 226: 85-96, 2001.
11. Ferguson AV and Washburn DLS. Angiotensin II: a peptidergic neurotransmitter in central autonomic pathways. Prog Neurobiol 54: 169-192, 1998.
12. Ferguson AV, Washburn DLS, and Bains JS. Regulation of autonomic pathways by angiotensin. Curr Opin Endocrinol Diab 6: 19-25, 1999.
13. Follwell MJ and Ferguson AV. Adrenomedullin influences magnocellular and parvocellular neurons of paraventricular nucleus via separate mechanisms. Am J Physiol Regul Integr Comp Physiol 283: R1293-R1302, 2002.
14. Follwell MJ and Ferguson AV. Cellular mechanisms of orexin actions on paraventricular nucleus neurones in rat hypothalamus. J Physiol 545: 855-867, 2002.
15. Ganong WF and Murakami K. The role of angiotensin II in the regulation of ACTH secretion. Ann NY Acad Sci 512: 176-186, 1987.
16. Gehlert DR, Gackenheimer SL, and Schober DA. Autoradiographic localization of subtypes of angiotensin II antagonist binding in the rat brain. Neuroscience 44: 501-514, 1991.
17. Gelband CH, Warth JD, Mason HS, Zhu M, Moore JM, Kenyon JL, Horowitz B, and Sumners C. Angiotensin II type I receptor-mediated inhibition of K+ channel subunit kv2.2 in brain stem and hypothalamic neurons. Circ Res 84: 352-359, 1999.
18. Hoffman NW, Tasker JG, and Dudek FE. Immunohistochemical differentiation of electrophysiologically defined neuronal populations in the region of the rat hypothalamic paraventricular nucleus. J Comp Neurol 307: 405-416, 1991.
19. Israel A, Plunkett LM, and Saavedra JM. Quantitative autoradiographic characterization of receptors for angiotensin II and other neuropeptides in individual brain nuclei and peripheral tissues from single rats. Cell Mol Neurobiol 5: 211-222, 1985.
20. Latchford KJ and Ferguson AV. Angiotensin II activates a nitric-oxide-driven inhibitory feedback in the rat paraventricular nucleus. J Neurophysiol 89: 1238-1244, 2003.
21. Latchford KJ and Ferguson AV. ANG II-induced excitation of paraventricular nucleus magnocellular neurons: a role for glutamate interneurons. Am J Physiol Regul Integr Comp Physiol 286: R894-R902, 2004.
22. Lenkei Z, Palkovits M, Corvol P, and Llorens-Cortes C. Distribution of angiotensin type-1 receptor mesenger RNA expression in the adult rat brain. Neuroscience 82: 827-841, 1998.
23. Lenkei Z, Corvol P, and Llorens-Cortes C. The angiotensin receptor subtype AT1A predominates in rat forebrain areas involved in blood pressure, body fluid homeostasis and neuroendocrine control. Brain Res Mol Brain Res 30: 53-60, 1994.
24. Lenkei Z, Palkovits M, Corvol P, and Llorens-Cortes C. Expression of angiotensin type-1 (AT1) and type-2 (AT2) receptor mRNAs in the adult rat brain: a functional neuroanatomical review. Front Neuroendocrinol 18: 383-439, 1997.
25. Lenkei Z, Palkovits M, Corvol P, and Llorens-Cortes C. Distribution of angiotensin TYPE-I receptor messenger RNA expression in the adult rat brain. Neuroscience 82: 827-841, 1998.
26. Li DP, Chen SR, and Pan HL. Angiotensin II stimulates spinally projecting paraventricular neurons through presynaptic disinhibition. J Neurosci 23: 5041-5049, 2003.
27. Li DP and Pan HL. Angiotensin II attenuates synaptic GABA release and excites paraventricular-rostral ventrolateral medulla output neurons. J Pharmacol Exp Ther 2005.
28. Li Z and Ferguson AV. Angiotensin II responsiveness of rat paraventricular and subfornical organ neurons in vitro. Neuroscience 55: 197-207, 1993.
29. A by angiotensin II. Neuroscience 71: 133-145, 1996.
30. Lind RW, Swanson LW, Bruhn TO, and Ganten D. The distribution of angiotensin II-immunoreactive cells and fibers in the paraventriculohypophyseal system of the rat. Brain Res 338: 81-89, 1985.
31. Luther JA, Daftary SS, Boudaba C, Gould GC, Halmos KC, and Tasker JG. Neurosecretory and non-neurosecretory parvocellular neurones of the hypothalamic paraventricular nucleus express distinct electrophysiological properties. J Neuroendocrinol 14: 929-932, 2002.
32. Mendelsohn FAO, Quirion R, Saavedra JM, Aguilera G, and Catt KJ. Autoradiographic localization of angiotensin II receptors in rat brain. Proc Natl Acad Sci USA 81: 1575-1579, 1984.
33. Nagatomo T, Inenaga K, and Yamashita H. Transient outward current in adult supraoptic neurones with slice patch-clamp technique: inhibition by angiotensin II. J Physiol (Lond) 485: 87-96, 1995.
34. Oldfield BJ, Davern PJ, Giles ME, Allen AM, Badoer E, and Mc-Kinley MJ. Efferent neural projections of angiotensin receptor (AT1) expressing neurones in the hypothalamic paraventricular nucleus of the rat. J Neuroendocrinol 13: 139-146, 2001.
35. Ono K, Honda E, and Inenaga K. Angiotensin II induces inward currents in subfornical organ neurones of rats. J Neuroendocrinol 13: 517-523, 2001.
36. 1 receptors in the brain. Regul Pept 44: 95-107, 1993.
37. Plotsky PM, Sutton SW, Bruhn TO, and Ferguson AV. Analysis of the role of angiotensin II in the mediation of adrenocorticotropin secretion. Endocrinology 122: 538-545, 1988.
38. Shoji M, Share L, and Crofton JT. Effect on vasopressin release of microinjection of angiotensin II into the paraventricular nucleus of concious rats. Neuroendocrinology 50: 327-333, 1989.
39. Song K, Zhuo J, Allen AM, Paxinos G, and Mendelsohn FA. Angiotensin II receptor subtypes in rat brain and peripheral tissues. Cardiology 79: 45-54, 1991.
40. Spinedi E and Rodriguez G. Angiotensin II and adrenocorticotropin release: mediation by endogenous corticotropin-releasing factor. Endocrinology 119: 1397-1402, 1986.
41. Stern JE. Electrophysiological and morphological properties of preautonomic neurones in the rat hypothalamic paraventricular nucleus. J Physiol 537: 161-177, 2001.
42. Sumners C and Gelband CH. Neuronal ion channel signaling pathways: modulation by angiotensin II. Cell Signal 10: 303-311, 1998.
43. Sumners C, Raizada MK, Kang J, Lu D, and Posner P. Receptor-mediated effects of angiotensin II on neurons. Front Neuroendocrinol 15: 203-230, 1994.
44. 2+ currents: intracellular mechanisms. Am J Physiol Cell Physiol 271: C154-C163, 1996.
45. Swanson LW and Sawchenko PE. Paraventricular nucleus: a site for the integration of neuroendocrine and autonomic mechanisms. Neuroendocrinology 31: 410-417, 1980.
46. Tasker JG and Dudek FE. Electrophysiological properties of neurones in the region of the paraventricular nucleus in slices of rat hypothalamus. J Physiol (Lond) 434: 271-293, 1991.
47. Yang B and Ferguson AV. Orexin-A depolarizes nucleus tractus solitarius neurons through effects on nonselective cationic and K+ conductances. J Neurophysiol 89: 2167-2175, 2003.
48. Yang CR, Phillips MI, and Renaud LP. Angiotensin II receptor activation depolarizes rat supraoptic neurons in vitro. Am J Physiol Regul Integr Camp Physiol 263: R1333-R1338, 1992.
49. Zhu M, Gelband CH, Posner P, and Sumners C. Angiotensin II decreases neuronal delayed rectifier potassium current: role of calcium/calmodulin- dependent protein kinase II. J Neurophysiol 82: 1560-1568, 1999.