The expression and function of Sgt1 protein in eukaryotic cells

Acta Neurobiologiae Experimentalis

Volumn 65, Issue 2, 2005, Pages 161-165

  Spiechowicz, Magdalena ^a   Filipek, Anna ^a  

^a NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY   (Poland)

Author keywords

Brain tissue; Plant; Sgt1 expression; Target proteins; Yeast and mammalian cells

Indexed keywords

GENE PRODUCT; MESSENGER RNA; PROTEIN CBF3; PROTEIN SGT1; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN TISSUE; CENTROMERE; CEREBELLUM; COMPLEX FORMATION; EUKARYOTIC CELL; GLIA CELL; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; NERVE CELL; NONHUMAN; NORTHERN BLOTTING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SKELETAL MUSCLE; SPLEEN; TISSUE DISTRIBUTION; WESTERN BLOTTING;

ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; BRAIN; CELL CYCLE PROTEINS; EUKARYOTIC CELLS; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; PROTEIN BINDING; RATS; RNA, MESSENGER;

EID: 21044439887     PISSN: 00651400     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Azevedo C, Sadanandom A, Kitagawa K, Freialdenhoven A, Shirasu K, Schulze-Lefert P (2002) The RAR1 interactor SGT1, an essential component of R gene-triggered disease resistance. Science 295: 2073-2076.
2. Bansal PK, Abdulle R, Kitagawa K (2004) Sgt1 associates with Hsp90: an initial step of assembly of the core kinetochore complex. Mol Cell Biol 24: 8069-8079.
3. Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenolchloroform extraction. Anal Biochem 162: 156-159.
4. Dubacq C, Guerois R, Courbeyrette R, Kitagawa K, Mann C (2002) Sgt1p contributes to cyclic AMP pathway activity and physically interacts with the adenylyl cyclase Cyr1p/Cdc35p in budding yeast. Eukaryot Cell 1: 568-582.
5. Filipek A, Kuznicki J (1998) Molecular clonning and expression of a mouse brain cDNA encoding a novel protein target of calcyclin. J Neurochem 70: 1793-1798.
6. Gray WM, Muskett PR, Chuang HW, Parker JE (2003) Arabidopsis SGT1b is required for SCF(TIR1)-mediated auxin response. Plant Cell 15: 1310-1319.
7. Hubert DA, Tornero P, Belkhadir Y, Krishna P, Takahashi A, Shirasu K, Dangl JL (2003) Cytosolic HSP90 associates with and modulates the Arabidopsis RPM1 disease resistance protein. EMBO J 22: 5679-5689.
8. Jastrzebska B, Filipek A, Nowicka D, Kaczmarek L and Kuznicki J. (2000) Calcyclin (S100A6) binding protein (CacyBP) is highly expressed in brain neurons. J Histochem Cytochem 48: 1195-1202.
9. Kitagawa K, Skowyra D, Elledge SJ, Harper JW, Hieter P (1999) SGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complex. Mol Cell 4: 21-33.
10. Lee YT, Jacob J, Michowski W, Nowotny M, Kuznicki J, Chazin WJ (2004) Human Sgt1 binds HSP90 through the CHORD-Sgt1 domain and not the tetratricopeptide repeat domain. J Biol Chem 279: 16511-16517.
11. Leister RT, Dahlbeck D, Day B, Li Y, Chesnokova O, Staskawicz BJ (2005) Molecular genetic evidence for the role of SGT1 in the intramolecular complementation of Bs2 protein activity in nicotiana benthamiana. Plant Cell 17: 1268-1278.
12. Lingelbach LB, Kaplan KB (2004) The interaction between Sgt1p and Skp1p is regulated by HSP90 chaperones and is required for proper CBF3 assembly. Mol Cell Biol 24: 8938-8950.
13. Liu Y, Burch-Smith T, Schiff M, Feng S, Dinesh-Kumar S (2004) Molecular chaperone Hsp90 associates with resistance protein N and its signaling proteins SGT1 and Rar1 to modulate an innate immune response in plants. J Biol Chem 279: 2101-2108.
14. Matsuzawa S, Reed J. (2001) Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses. Mol Cell 7: 915-926.
15. Niikura Y, Kitagawa K (2003) Identification of a novel splice variant: human SGT1B (SUGT1B). DNA Seq 14: 436-441.
16. Nowotny M, Spiechowicz M, Jastrzebska B, Filipek A, Kitagawa K, Kuznicki J (2003) Calcium-regulated interaction of Sgt1 with S100A6 (calcyclin) and other S100 proteins. J Biol Chem 278: 26923-26928.
17. Rodrigo-Brenni MC, Thomas S, Bouck DC, Kaplan KB (2004) Sgt1p and Skp1p modulate the assembly and turnover of CBF3 complexes required for proper kinetochore function. Mol Biol Cell 15: 3366-3378.
18. Shirasu K, Schulze-Lefert P (2003) Complex formation, promiscuity and multi-functionality: protein interactions in disease-resistance pathways. Trends Plant Sci. 8: 252-258.
19. Steensgaard P, Garre M, Muradore I, Transidico P, Nigg EA, Kitagawa K, Earnshaw WC, Faretta M, Musacchio A (2004) Sgt1 is required for human kinetochore assembly. EMBO Rep 5: 626-631.
20. Takahashi A, Casais C, Ichimura K, Shirasu K (2003) HSP90 interacts with RAR1 and SGT1 and is essential for RPS2-mediated disease resistance in Arabidopsis. Proc Natl Acad Sci U S A. 100: 11777-11782.
21. Yamamoto T, Mori Y, Ishibashi T, Uchiyama Y, Sakaguchi N, Furukawa T, Hashimoto J, Kimura S, Sakaguchi K (2004) Characterization of Rad6 from a higher plant, rice (Oryza sativa L.) and its interaction with Sgt1, a subunit of the SCF ubiquitin ligase complex. Biochem Biophys Res Commun 314: 434-439.
22. Zou X, Ji C, Wang L, Wu M, Zheng H, Xu J, Jin F, Gu S, Ying K, Xie Y, Mao Y (2004) Molecular cloning and characterization of SGT1.2, a novel splice variant of Homo sapiens SGT1. DNA Seq 15: 140-143.