The frequencies of micronuclei induced by cisplatin in newborn rat astrocytes are increased by 50-Hz, 7.5- and 10-mT electromagnetic fields

Environmental Health and Preventive Medicine

Volumn 10, Issue 3, 2005, Pages 138-143

  Miyakoshi, Yuichi ^a   Yoshioka, Hayato ^a   Toyama, Yoshimitsu ^a   Suzuki, Yuji ^a   Shimizu, Hidesuke ^a  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Astrocyte; Cisplatin; Electromagnetic fields; Genotoxicity; Micronucleus test

Indexed keywords

ACRIDINE ORANGE; CARCINOGEN; CISPLATIN; GLIAL FIBRILLARY ACIDIC PROTEIN; MUTAGENIC AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN CELL; BRAIN TUMOR; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EXPOSURE; ELECTROMAGNETIC FIELD; ENVIRONMENTAL EXPOSURE; EPIDEMIOLOGICAL DATA; FLUORESCENCE MICROSCOPE; GENOTOXICITY; IN VIVO STUDY; LEUKEMIA; MALE; MICRONUCLEUS TEST; NERVE CELL CULTURE; NEWBORN; NONHUMAN; OCCUPATIONAL EXPOSURE; RAT;

ANIMALIA;

EID: 21044433793     PISSN: 1342078X     EISSN: None     Source Type: Journal    
DOI: 10.1265/ehpm.10.138     Document Type: Article

References (45)

1. Miller RD, Neuberger JS, Gerald KB. Brain cancer and leukemia and exposure to power-frequency (50- to 60-Hz) electric and magnetic fields. Epedemiol Rev. 1997; 19: 273-293.
2. Kheifets LI. Electric and magnetic field exposure and brain cancer: a review. Bioelectromagnetics. 2001; Sup 5: S120-S131.
3. McCann J, Dietrich F, Raffery C, Martin A. A critical review of the genotoxic potential of electric and magnetic fields. Mutat Res. 1993; 297: 61-95.
4. McCann J, Dietrich F, Raffery C. The genotoxic potential of electric and magnetic fields: an update. Mutat Res. 1998; 411: 45-86.
5. Heddle LA, Hite M, Kierkhart B, Mavourin K, MacGregor JT, Newell GW, Salamone MF. The induction of micronuclei as a measure of genotoxicity, A report of the US Environmental Protection Agency Gene-Tox Program. Mutat Res. 1983; 123: 61-118.
6. Toga W, Suzuki Y, Shimizu H. In vivo micronuclei test in rat newborn astrocytes. 8th International Conference on Environmental Mutagens. Shizuoka, October, 2001. Mutat Res. 2001; 483 (Suppl. 1): S162.
7. Miyakoshi Y, Suzuki Y, Ooida M, Takahashi A, Tsukui M. Micronucleus test using cultured new born rat astrocytes. Ind Health. 1999; 37: 95-102.
8. Suzuki Y, Shimizu H, Kim SU. Induction of micronucleus in NSC19 motoneuron cell line by genotoxic chemicals. Neuro Toxicol. 1997; 18: 325-330.
9. Kastenbaum MA, Bowman KO. Tables for determining the statistical significance of mutation frequencies. Mutat Res. 1970; 9: 527-549.
10. Loscher W, Mevissen M, Lehmacher W, Stamm A. Tumor promotion in a breast cancer model by exposure to a weak alternating magnetic field. Cancer Lett. 1993; 71: 75-81.
11. Thun-Battersby S, Mevissen M, Loscher W. Exposure of Sprague-Dawley rats to a 50-Hertz, 100-μTesla magnetic field for 27 weeks facilitates mammary tumorgenesis in the 7, 12-dimethylbenz (a) anthracene model of breast cancer. Cancer Res. 1999; 59: 3627-3633.
12. Mevissen M, Kietzmann M, Loscher W. In vivo exposure of rats to a weak alterinating magnetic field increases ornithine decarboxylase activity in the mammary gland by a similar extent as the carcinogen DMBA. Cancer Lett. 1995; 90: 207-214.
13. Wei M, Guizzetti M, Yost M, Costa LG. Exposure to 60-Hz magnetic fields and proliferation of human astrocytoma cells in vitro. Toxicol Appl Pharmacol. 2000; 162: 166-176.
14. Ooida M, Miyakoshi Y, Tsukui M, Liu D, Asanuma K, Suzuki Y. In vitro micronucleus test for six chemicals using cultured rat astrocytes. Environmental Sciences. 2000; 7: 57-69.
15. Sakaba H, Liu D, Tukui M, Asanuma K, Takahashi A, Suzuki Y. Micronucleus test with a metabolic activation system and cultured astrocytes. Jikeikai Med J. 2000; 47: 131-138.
16. Rozenxweig M, von Hoff DD, Slavik M, Muggia FM. Cis- diamminedichloroplatinum (II) a new aniticancer drug. Ann Intern Med. 1977; 86: 803-812.
17. Loehrer PJ. Diagnosis and treatment, drugs five years later. Ann Intern Med. 1984; 100: 704-713.
18. Benedict WF, Baker RL, Haroun L, Choi E, Ames BN. Mutagenicity and cancer chemotherapeutic agents in the Salmonell-microsome test. Cancer Res. 1977; 37: 2209-2213.
19. Rosenberg B. Fundamental studies with cisplatin. Cancer. 1985; 55: 2303-2316.
20. Beck DJ, Brubaker RR. Mutagenicity properties of cis-platinum (II) diamminedichloride in E. coli. Mutat Res. 1975; 66: 181-189.
21. Turnbull D, Popescu NC, DiPaolo JA, Mythr BC. cis-Platinum (II) diammine dichloride causes mutation, transformation and sister-chromatid exchanges in cultured mammalian cells. Mutat Res. 1979; 66: 267-275.
22. Pleskova I, Blasko M, Siracky J. Chromosomal aberrations, sister chromatid exchange (SCEs) and micronuclei induction with three platinum compounds (cis-DDP, CHIP, CBDCA) in V79 cells in vitro. Neoplasma. 1984; 31: 655-659.
23. Adey WR. Biological effects of electromagnetic fields. J Cell Biochem. 1993; 51: 410-416.
24. Frey AH. Electromagnetic field interactions with biological systems. FASEB J. 1993; 7: 272-281.
25. Koifman S. Electromagnetic fields-a cancer promoter? Med Hypotheses. 1993; 41: 23-27.
26. Loscher W, Mevissen M. Animal studies on the role of 50/60 Hertz magnetic fields in carcinogenesis. Life Sci. 1994; 54: 1531-1543.
27. Reiter RJ. Static and extremely low frequency electromagnetic field exposure-reported effects on the circardian production of melatonin. J Cell Biochem. 1993; 51: 394-403.
28. Walleczek J. Electromagnetic field effects on cells of the immune system: the role of calcium signalin. FASEB J. 1992; 6: 3177-3185.
29. Repacholi MH, Greenbaum B. Interaction of static and extremely low frequency electric and magnetic fields with living systems: health effects and research needs. Bioelectromagnetics. 1999; 20: 133-160.
30. Schernhammer ES, Schulmeister K. Melatonin and cancer risk: does light at night compromise physiologic cancer protection by lowering serum melatonin levels? Br J Cancer. 2004; 90: 941-943.
31. Stevens RG, Davis S, Thomas DB, Anderson LE, Wilson BW. Electric power, pineal function, and the risk of breast cancer. FASEB J. 1992; 6: 853-860.
32. Karasek M, Lerchl A. Melatonin and magnetic fields. Neuroendocrinol Lett. 2002; 23 (Suppl 1): 84-87.
33. Loscher W, Liburdy RP. Animal and cellular studies on carcinogenesis effects of low frequency (50/60-Hz) magnetic fields. Mutat Res. 1998; 410: 185-220.
34. Phillip JL. Effects of electromagnetic field exposure on gene transcription. J Cell Biochem. 1993; 51: 381-386.
35. Lin H, Bland M, Rossol-Haseroth K, Goodman R. Regulating genes with electromagnetic response elements. J Cell Biochem. 2001; 81: 143-148.
36. Marcu KB, Bossome SA, Patel AJ. MYC function and regulation. Annu Rev Biochem. 1992; 61: 809-860.
37. Tofani S, Barone M, Berardelli M, et al. Static and ELF magnetic fields enhance the in vivo anti-tumor efficacy of cis-platin against lewis lung carcinoma. But not of cyclophosphamide against B16 melanotic melanoma. Pharmacol Res. 2003; 48: 83-90.
38. Shimizu H, Akiyama M, Suzuki Y, Hayashi K. The effects of magnetic field on mutagenic activity. Mutat Res. 1989; 16: 377.
39. Okonogi H, Nakagawa M, Tsuji Y. The effects of a 4.7 tesla static magnetic field on the frequency of micronucleated cells induced by mitomycin C. Tohoku J Exp Med. 1996; 180: 209-215.
40. Tsuji Y, Nakagawa M, Suzuki Y. Five-tesla static magnetic fields suppress food and water consumption and weight gain in mice. Ind Health. 1996; 34: 347-357.
41. Satoh M, Tsuji Y, Watanabe Y, Okonogi H, Suzuki Y, Nakagawa M, Shimizu H. Metallothionein content increased in the liver of mice exposed to magnetic fields. Arch Toxicol. 1996; 70: 315-318.
42. Watanabe Y, Nakagawa M, Miyakoshi Y. Enhancement of lipid peroxidation in the liver mice exposed to magnetic fields. Ind Health. 1997; 35: 285-290.
43. Suzuki Y, Ikehata M, Nakamura K, Nishioka M, Asanuma K, Koana T, Shimizu H. Induction of micronuclei in mice exposed to static magnetic fields. Mutagenesis. 2001; 16: 499-501.
44. World Health Organization International Agency for Research on Cancer. IARC monographs on the evaluation of carcinogenic risks to humans, volume 80, Non-ionizing radiation, part 1: static and extremely low-frequency (ELF) electric and magnetic fields. Lyon France; IARC Press; 2002. p. 331-338.
45. World Health Organization International Agency for Research on Cancer. IARC monographs on the evaluation of carcinogenic risks to humans, volume 80, Non-ionizing radiation, part 1: static and extremely low-frequency (ELF) electric and magnetic fields. Lyon France; IARC Press; 2002. p. 51-66.