Decreased 5-HT2C receptor binding in the cerebral cortex and brain stem during pancreatic regeneration in rats

Molecular and Cellular Biochemistry

Volumn 272, Issue 1-2, 2005, Pages 165-170

  Mohanan, Valiya Veettil ^a   Chathu, Finla ^a   Paulose, Cheramadathikudyil S ^a  

^a Department of Physics   (India)

Author keywords

5 HT2C receptor; Brain stem; Cerebral cortex; Pancreas; Regeneration

Indexed keywords

MESULERGINE; SEROTONIN; SEROTONIN 2C RECEPTOR; TRITIUM; ERGOLINE DERIVATIVE; SEROTONIN ANTAGONIST;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING COMPETITION; BRAIN CORTEX; BRAIN STEM; CONTROLLED STUDY; NONHUMAN; PANCREAS FUNCTION; PANCREAS RESECTION; PROTEIN FUNCTION; RAT; RECEPTOR BINDING; SCATCHARD PLOT; SEROTONINERGIC SYSTEM; TISSUE REGENERATION; ANIMAL; METABOLISM; PANCREAS; PHYSIOLOGY; REGENERATION; WISTAR RAT;

ANIMALS; BINDING, COMPETITIVE; BRAIN STEM; CEREBRAL CORTEX; ERGOLINES; PANCREAS; RATS; RATS, WISTAR; RECEPTOR, SEROTONIN, 5-HT2C; REGENERATION; SEROTONIN; SEROTONIN ANTAGONISTS;

EID: 20944441560     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11010-005-7030-0     Document Type: Article

References (34)

1. Liang Y, Luo S, Cincotta AH: Long-term infusion of norepinephrine plus serotonin into the ventromedial hypothalamus impairs pancreatic islet function. Metabolism 48: 1287-1289, 1999 10.1016/S0026-0495(99)90269-X
2. Bereiter DA, Rohner-Jeanrenaud F, Berthoud HR, Jeanrenaud B: CNS modulation of pancreatic endocrine function: Multiple modes of expression. Diabetologia 20: 417-425, 1981 10.1007/BF00254511
3. Azmitia EC, Gannon P: Anatomy of the serotonergic system in the primate and sub-primate brain. J Adv Neurol 43: 407-468, 1986 1:STN:280:BimC38nktlc%3D
4. Martin GR, Humphrey PP: Receptors for 5-hydroxytryptamine: Current perspectives on classification and nomenclature. Neuropharmacology 33: 261-273, 1994 10.1016/0028-3908(94)90058-2
5. Mengod G, Nguyen H, Le H, Waeber C, Lubbert H, Palacios JM: The distribution and cellular localization of the serotonin 1C receptor mRNA in the rodent brain examined by in situ hybridization histochemistry. Comparison with receptor binding distribution. Neuroscience 35: 577-591, 1990 10.1016/0306-4522(90)90330-7
6. Welch JE, Saphier D: Central and peripheral mechanisms in the stimulation of adrenocortical secretion by the 5-hydroxytryptamine 2 agonist, 1-(2, 5-dimethoxy-4-iodophenyl)-2-aminopropane. J Pharmacol Exp Ther 270: 918-928, 1994 1:CAS:528:DyaK2cXmsVKqurk%3D
7. 2 receptor agonists DOI and alpha-methyl-5-HT on plasma glucose and insulin level in the rat. Eur J Pharmacol 187: 435-443, 1990 10.1016/0014-2999(90)90370-L
8. Martin JM, Lacy PF: The prediabetic period in partially pancreatectomised rats. Diabetes 12: 238-242, 1963
9. Burr IM, Slonim AE, Sharp R: Interactions of acetylcholine and epinephrine on the dynamics of insulin release in vitro. J Clin Invest 58: 230-239, 1976 1:CAS:528:DyaE28XltFOjtL4%3D
10. Campfield LA, Smith FJ: Modulation of insulin secretion by the autonomic nervous system. Brain Res Bull 4: 103-107, 1980 10.1016/ 0361-9230(80)90238-5
11. Renuka TR, Ani V Das, Paulose CS: Alterations in the muscarinic M1 and M3 receptor gene expression in the brain stem during pancreatic regeneration and insulin secretion in rats. Life Sci ([0-9]+): 2269-2280, 2004 10.1016/j.lfs.2004.03.034
12. Biju MP, Pyroja S, Rajeshkumar NV, Paulose CS: Hypothalamic GABA receptor functional regulation and liver cell proliferation. Mol Cell Biochem 216: 65-70, 2001 10.1023/A:1011052329346
13. Pearson KW, Scott D, Torrance B: Effects of partial surgical pancreatectomy in rats. Gastroenterology 72: 469-473, 1977 1:STN:280:CSiD1M7ps1Q%3D
14. Zangen DH, Bonner-Weir S, Lee CH, Latimer JB, Miller CP, Habener JF, Weir GC: Reduced insulin GLUT2 and IDX-1 in b-cells after partial pancreatectomy. Diabetes 46: 258-264, 1997 1:CAS:528:DyaK2sXmtlyksw%3D%3D
15. Glowinski J, Iverson LL: Regional studies of catecholamines in the rat brain: The disposition of [ 3 H]Norepinephrine, [ 3 H]DOPA in various regions of the brain. J Neurochem 13: 655-669, 1966 1:CAS:528:DyaF28Xks1Kqtrw%3D
16. Paulose CS, Dakshinamurti K, Packer S, Stephens NL: Sympathetic stimulation and hypertension in pyridoxine deficient adult rat. Hypertension 11: 387-391, 1988 1:CAS:528:DyaL1cXkt1ajtr8%3D
17. 2C receptor RNA editing alters receptor basal activity: Implications for serotonergic signal transduction. J Neurochem 73: 1711-1717, 1999 1:CAS:528:DyaK1MXmtlOhtr0%3D
18. Lowry OH, Rosenbrough NJ, Farr AL, Randall RJ: Protein measurement with folin phenol reagent. J Biol Chem 193: 265-275, 1951 1:CAS:528:DyaG38XhsVyrsw%3D%3D
19. Scatchard G: The attractions of proteins for small molecules and ions. Ann NY Acad Sci 51: 660-672, 1949 1:CAS:528:DyaH1MXktFGktw%3D%3D
20. Chen Y, Prusoff WH: Relationship between the inhibition constant and the concentration of an inhibitor that cause a 50% inhibition of an enzyme reaction. Biochem Pharmacol 22: 3099-3108, 1973 4202581
21. 1A receptor protein in the cerebral cortex and brain stem during pancreatic regeneration in rats. Neurochem Res 30: 25-32, 2005 1:CAS:528:DC%2BD2MXotV2ntQ%3D%3D
22. Brockenbrough S, Weir GC, Bonner-Weir S: Discordance of exocrine and endocrine growth after 90% pancreatectomy in rats. Diabetes 37: 232-236, 1988 1:STN:280:BieB2s7otVE%3D
23. Liu YQ, Montanya E, Leahy JL: Increased islet DNA synthesis and glucose-derived lipid and amino acid production in association with beta-cell hyperproliferation in normoglycaemic 60% pancreatectomy rats. Diabetologia 44: 1026-1033, 2001 1:CAS:528:DC%2BD3MXlsFCgsb8%3D
24. Holst JJ, Schwartz TW, Knuhtsen S, Jensen SL, Nielsen OV: Autonomic control of the endocrine secretion from isolated, perfused pig pancreas. J Auton Nerv Sys 17: 71-84, 1986 1:CAS:528:DyaL28XlvVCntr0%3D
25. Bitar MS, Koulu M, Linnoila M: Diabetes-induced changes in monoamine concentrations of rat hypothalamic nuclei. Brain Res 409: 236-242, 1987 1:CAS:528:DyaL2sXktlOms74%3D
26. Kuhn DM, Wolf WA, Lovenberg W: Review of the role of the central serotonergic neuronal system in blood pressure regulation. Hypertension 2: 243-255, 1980 1:CAS:528:DyaL3cXksVaqtrw%3D
27. 2 receptor agonists increase spontaneous sympathetic nerve discharge. Eur J Pharmacol 151: 113-116, 1988 1:CAS:528:DyaL1cXkvVKit7k%3D
28. Hoyer D: Functional correlates of 5-HT1 recognition sites. J Recept Res 8: 59-81, 1988 1:CAS:528:DyaL1cXitFKgtLs%3D
29. Jackson J, Padayatti PS, Paul T, Paulose CS: Platelet monoamine changes in diabetic patients and streptozotocin induced diabetic rats. Curr Sci 72: 137-139, 1997
30. Baudrie V, Chouloff F: Mechanisms involved in the hyperglycemic effect of the 5-HT1C/5-HT2 receptor agonist, DOI. Eur J Pharmacol 213: 41-46, 1992 1:CAS:528:DyaK38XisV2it7o%3D
31. 2C/2B receptor agonist 1-(3-chlorophenyl) piperazine on plasma glucose levels of man. Eur J Pharmacol 307: 75-80, 1996 1:CAS:528:DyaK28XjvFGju7o%3D
32. F Rossand LE Limbird: P.A. Insel (ed) 1987 Adrenergic Receptors in Man Marceldecker Inc. New York and Basel 161-199
33. Perry BD, Stolk JM, Vantini G, Guchhait RB, U'Prichard DC: Strain differences in rat brain epinephrine synthesis: Regulation of alpha-adrenergic receptor number by epinephrine. Science 221: 1297-1299, 1983 1:CAS:528:DyaL3sXlslSiuro%3D
34. Bagdy G, Calogero AE, Murphy DL, Szemeredi K: Serotonin agonists cause parallel activation of the sympatho-adrenomedullary system and the hypothalamo-pituitary-adrenocortical axis in conscious rats. Endocrinology 125: 2664-2669, 1989 1:CAS:528:DyaK3cXntVKqtw%3D%3D