Proteomic analysis of differential protein expression in human atherosclerotic plaque progression

Journal of Pathology

Volumn 206, Issue 1, 2005, Pages 39-45

  Donners, Marjo M P C ^a   Verluyten, Monique J ^a   Bouwman, Freek G ^b   Mariman, Edwin C M ^b   Devreese, Bart ^c   Vanrobaeys, Frank ^c   van Beeumen, Jozef ^c   van den Akker, Luc H J M ^d   Daemen, Mat J A P ^a   Heeneman, Sylvia ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c GHENT UNIVERSITY   (Belgium)

^d Zuyderland Medical Centre   (Netherlands)

Author keywords

1 antitrypsin; 2D gel electrophoresis; Atherosclerosis; Human; Proteomics; Vinexin

Indexed keywords

ALPHA 1 ANTITRYPSIN; ISOPROTEIN; PROTEOME; UNCLASSIFIED DRUG; VINEXIN BETA;

ADULT; AGED; ARTERY THROMBOSIS; ARTICLE; ATHEROSCLEROTIC PLAQUE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; TWO DIMENSIONAL GEL ELECTROPHORESIS; WESTERN BLOTTING;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AGED; ALPHA 1-ANTITRYPSIN; ARTERIOSCLEROSIS; DISEASE PROGRESSION; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENDOTHELIAL CELLS; GENE EXPRESSION; HUMANS; IMMUNOHISTOCHEMISTRY; MACROPHAGES; MALE; MASS SPECTROMETRY; MIDDLE AGED; MUSCLE PROTEINS; NEUTROPHILS; PROTEOMICS; THROMBOSIS;

EID: 20944440658     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/path.1749     Document Type: Article

References (18)

1. Lusis AJ. Atherosclerosis. Nature 2000; 407: 233-241.
2. Faber BC, Cleutjens KB, Niessen RL, et al. Identification of genes potentially involved in rupture of human atherosclerotic plaques. Circ Res 2001; 89: 547-554.
3. Hiltunen MO, Tuomisto TT, Niemi M, et al. Changes in gene expression in atherosclerotic plaques analyzed using DNA array. Atherosclerosis 2002; 165: 23-32.
4. Gygi SP, Rochon Y, Franza BR, Aebersold R. Correlation between protein and mRNA abundance in yeast. Mol Cell Biol 1999; 19: 1720-1730.
5. Moore BR, Free SJ. Protein modification and its biological role. Int J Biochem 1985; 17: 283-289.
6. Bichsel VE, Liotta LA, Petricoin EF 3rd. Cancer proteomics: from biomarker discovery to signal pathway profiling. Cancer J 2001; 7: 69-78.
7. You SA, Archacki SR, Angheloiu G, et al. Proteomic approach to coronary atherosclerosis shows ferritin light chain as a significant marker: evidence consistent with iron hypothesis in atherosclerosis. Physiol Genomics 2003; 13: 25-30.
8. Virmani R, Kolodgie FD, Burke AP, Farb A, Schwartz SM. Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions. Arterioscler Thromb Vasc Biol 2000; 20: 1262-1275.
9. Devreese B, Janssen KP, Vanrobaeys F, Van Herp F, Martens GJ, Van Beeumen J. Automated nanoflow liquid chromatography-tandem mass spectrometry for a differential display proteomic study on Xenopus laevis neuroendocrine cells. J Chromatogr A 2002; 976: 113-121.
10. Pietrogrande MC, Marchetti N, Dondi F, Righetti PG. Spot overlapping in two-dimensional polyacrylamide gel electrophoresis maps: relevance to proteomics. Electrophoresis 2003; 24: 217-224.
11. Kioka N, Sakata S, Kawauchi T, et al. Vinexin: a novel vinculin-binding protein with multiple SH3 domains enhances actin cytoskeletal organization. J Cell Biol 1999; 144: 59-69.
12. Stastny JJ, Fosslien E. Quantitative alteration of some aortic intima proteins in fatty streaks and fibro-fatty lesions. Exp Mol Pathol 1992; 57: 205-214.
13. Hafeez W, Ciliberto G, Perlmutter DH. Constitutive and modulated expression of the human alpha 1 antitrypsin gene: different transcriptional initiation sites used in three different cell types. J Clin Invest 1992; 89: 1214-1222.
14. Hollander W, Colombo MA, Kirkpatrick B, Paddock J. Soluble proteins in the human atherosclerotic plaque. With spectral reference to immunoglobulins, C3-complement component, alpha 1-antitrypsin and alpha 2-macroglobulin. Atherosclerosis 1979; 34: 391-405.
15. Janciauskiene S. Conformational properties of serine proteinase inhibitors (serpins) confer multiple pathophysiological roles. Biochim Biophys Acta 2001; 1535: 221-235.
16. Dichtl W, Moraga F, Ares MP, et al. The carboxyl-terminal fragment of alpha1-antitrypsin is present in atherosclerotic plaques and regulates inflammatory transcription factors in primary human monocytes. Mol Cell Biol Res Commun 2000; 4: 50-61.
17. Mizon C, el Yamani J, Colombel JF, et al. Deglycosylation of alpha 1-proteinase inhibitor is impaired in the faeces of patients with active inflammatory bowel disease (Crohn's disease). Clin Sci (Lond) 1991; 80: 517-523.
18. Hrycaj P, Nayyar S, Stanworth DR, Muller W. Microheterogeneity of alpha 1-antitrypsin in relation to the concentration of its complex with immunoglobulin A in the sera of patients with rheumatoid arthritis. Clin Exp Rheumatol 1996; 14: 119-123.