Discovery of potent and selective phenylalanine based dipeptidyl peptidase IV inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 10, 2005, Pages 2533-2536

  Xu, Jinyou ^a   Wei, Lan ^a   Mathvink, Robert ^a   He, Jiafang ^a   Park, You Jung ^a   He, Huaibing ^a   Leiting, Barbara ^a   Lyons, Kathryn A ^a   Marsilio, Frank ^a   Patel, Reshma A ^a   Wu, Joseph K ^a   Thornberry, Nancy A ^a   Weber, Ann E ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

DPP IV

Indexed keywords

5 OXO 1,2,4 OXADIAZOLE; AMIDE; DIPEPTIDYL PEPTIDASE; DIPEPTIDYL PEPTIDASE IV INHIBITOR; ENZYME INHIBITOR; PHENYLALANINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; DRUG POTENCY; DRUG SELECTIVITY; DRUG SYNTHESIS; IC 50; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

EID: 20944439078     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.03.055     Document Type: Article

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