Diastereoselective synthesis and configuration-dependent activity of (3-substituted-cycloalkyl)glycine pyrrolidides and thiazolidides as dipeptidyl peptidase IV inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 4, 2004, Pages 859-863

  Ashton, Wallace T ^a   Dong, Hong ^a   Sisco, Rosemary M ^a   Doss, George A ^a   Leiting, Barbara ^a   Patel, Reshma A ^a   Wu, Joseph K ^a   Marsilio, Frank ^a   Thornberry, Nancy A ^a   Weber, Ann E ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDYL PEPTIDASE IV INHIBITOR; ENZYME INHIBITOR; PYRROLIDINE DERIVATIVE; THIAZOLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; DIASTEREOISOMER; DRUG POTENCY; DRUG SYNTHESIS; IC 50; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 10744220490     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2003.12.013     Document Type: Article

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