Proprotein convertase genes in Xenopus development

Developmental Dynamics

Volumn 233, Issue 3, 2005, Pages 1038-1044

  Nelsen, Sylvia ^a   Berg, Linnea ^b   Wong, Crispin ^b   Christian, Jan L ^b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Embryogenesis; Furin; PC4; PC6; Proprotein convertase; Xenopus

Indexed keywords

FURIN; PROPROTEIN CONVERTASE 4; PROPROTEIN CONVERTASE 6; SERINE PROTEINASE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN; DEVELOPMENTAL GENETICS; EMBRYO; EMBRYO DEVELOPMENT; GENE EXPRESSION; GERM CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; ORTHOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TISSUE DISTRIBUTION; TISSUE SPECIFICITY; XENOPUS;

AMINO ACID SEQUENCE; ANIMALS; EMBRYO, NONMAMMALIAN; FURIN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GERM CELLS; ISOENZYMES; MOLECULAR SEQUENCE DATA; PROPROTEIN CONVERTASES; SEQUENCE ALIGNMENT; XENOPUS LAEVIS;

ANURA; XENOPUS (GENUS);

EID: 20744448964     PISSN: 10588388     EISSN: None     Source Type: Journal    
DOI: 10.1002/dvdy.20378     Document Type: Article

References (36)

1. Anderson ED, Molloy SS, Jean F, Fei H, Shimamura S, Thomas G. 2002. The ordered and compartment-specific autoproteolytic removal of the furin intramolecular chaperone is required for enzyme activation. J Biol Chem 277:12879-12890.
2. Beck S, Le Good JA, Guzman M, Ben Haim N, Roy K, Beermann F, Constam DB. 2002. Extraembryonic proteases regulate Nodal signalling during gastrulation. Nat Cell Biol 4:981-985.
3. Birsoy B, Berg L, Williams PH, Smith JC, Wylie CC, Christian JL, Heasman J. 2005. XPACE4 is a localized pro-protein convertase required for mesoderm induction and the cleavage of specific TGF(beta) proteins in Xenopus development. Development 132:591-602.
4. Christian JL, McMahon JA, McMahon AP, Moon RT. 1991. Xwnt-8, a Xenopus Wnt-1/int-1-related gene responsive to mesoderm-inducing growth factors, may play a role in ventral mesodermal patterning during embryogenesis. Development 111: 1045-1055.
5. Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A. 2003. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. Genome Res 13:2265-2270.
6. Constam DB, Robertson EJ. 2000a. SPC4/PACE4 regulates a TGFbeta signaling network during axis formation. Genes Dev 14:1146-1155.
7. Constam DB, Robertson EJ. 2000b. Tissue-specific requirements for the proprotein convertase furin/SPC1 during embryonic turning and heart looping. Development 127:245-254.
8. Constam DB, Calfon M, Robertson EJ. 1996. SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distinct sites during embryogenesis. J Cell Biol 134:181-191.
9. Cui Y, Brown JD, Moon RT, Christian JL. 1995. Xwnt-8b: a maternally expressed Xenopus Wnt gene with a potential role in establishing the dorsoventral axis. Development 121:2177-2186.
10. Cui Y, Jean F, Thomas G, Christian JL. 1998. BMP-4 is proteolytically activated by furin and/or PC6 during vertebrate embryonic development [in process citation]. EMBO J 17:4735-4743.
11. De Bie I, Savaria D, Roebroek AJ, Day R, Lazure C, Van de Ven WJ, Seidah NG. 1995. Processing specificity and biosynthesis of the Drosophila melanogaster convertases dfurin1, dfurin1-CRR, dfurin1-X, and dfurin2. J Biol Chem 270:1020-1028.
12. Frohman MA. 1993. Rapid amplification of complementary DNA ends for generation of full-length complementary DNAs: thermal RACE. Methods Enzymol 218:340-356.
13. Harland RM. 1991. In situ hybridization: an improved whole-mount method for Xenopus embryos. Methods Cell Biol 36:685-695.
14. Korner J, Chun J, O'Bryan L, Axel R. 1991. Prohormone processing in Xenopus oocytes: characterization of cleavage signals and cleavage enzymes. Proc Natl Acad Sci U S A 88:11393-11397.
15. Lennon G, Auffray C, Polymeropoulos M, Soares MB. 1996. The I.M.A.G.E. Consortium: an integrated molecular analysis of genomes and their expression. Genomics 33:151-152.
16. Lipkind GM, Zhou A, Steiner DF. 1998. A model for the structure of the P domains in the subtilisin-like prohormone convertases. Proc Natl Acad Sci U S A 95:7310-7315.
17. Mbikay M, Raffin-Sanson ML, Tadros H, Sirois F, Seidah NG, Chretien M. 1994. Structure of the gene for the testis-specific proprotein convertase 4 and of its alternate messenger RNA isoforms. Genomics 20:231-237.
18. Molloy SS, Anderson ED, Jean F, Thomas G. 1999. Bi-cycling the furin pathway: from TGN localization to pathogen activation and embryogenesis. Trends Cell Biol 9:28-35.
19. Nakagawa T, Murakami K, Nakayama K. 1993. Identification of an isoform with an extremely large Cys-rich region of PC6, a Kex2-like processing endoprotease. FEBS Lett 327:165-171.
20. Nakayama T, Snyder MA, Grewal SS, Tsuneizumi K, Tabata T, Christian JL. 1998. Smad8 acts downstream of BMP-4 to modulate its activity during vertebrate embryonic patterning. Development 125:857-867.
21. Nastos A, Pogge von Strandmann E, Weber H, Ryffel GU. 1998. The embryonic expression of the tissue-specific transcription factor HNF1alpha in Xenopus: rapid activation by HNF4 and delayed induction by mesoderm inducers. Nucleic Acids Res 26:5602-5608.
22. Nie GY, Li Y, Minoura H, Findlay JK, Salamonsen LA. 2003. Specific and transient up-regulation of proprotein convertase 6 at the site of embryo implantation and identification of a unique transcript in mouse uterus during early pregnancy. Biol Reprod 68:439-447.
23. Nieuwkoop PD, Faber J. 1967. Normal table of Xenopus laevis. Amsterdam: Amsterdam: North Holland Publishing Co.
24. Roebroek AJ, Creemers JW, Pauli IG, Kurzik-Dumke U, Rentrop M, Gateff EA, Leunissen JA, Van de Ven WJ. 1992. Cloning and functional expression of Dfurin2, a subtilisin-like proprotein processing enzyme of Drosophila melanogaster with multiple repeats of a cysteine motif. J Biol Chem 267:17208-17215.
25. Roebroek AJ, Umans L, Pauli IG, Robertson EJ, van Leuven F, Van de Ven WJ, Constam DB. 1998. Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin. Development 125:4863-4876.
26. Seidah NG, Day R, Hamelin J, Gaspar A, Collard MW, Chretien M. 1992. Testicular expression of PC4 in the rat: molecular diversity of a novel germ cell-specific Kex2/subtilisin-like proprotein convertase. Mol Endocrinol 6:1559-1570.
27. Spence MJ, Sucic JF, Foley BT, Moehring TJ. 1995. Analysis of mutations in alleles of the fur gene from an endoprotease-deficient Chinese hamster ovary cell strain. Somat Cell Mol Genet 21:1-18.
28. Tadros H, Chretien M, Mbikay M. 2001. The testicular germ-cell protease PC4 is also expressed in macrophage-like cells of the ovary. J Reprod Immunol 49:133-152.
29. Taylor NA, Van De Ven WJ, Creemers JW. 2003. Curbing activation: proprotein convertases in homeostasis and pathology. FASEB J 17:1215-1227.
30. Thomas G. 2002. Furin at the cutting edge: from protein traffic to embryogenesis and disease. Nat Rev Mol Cell Biol 3:753-766.
31. Torii S, Yamagishi T, Murakami K, Nakayama K. 1993. Localization of Kex2-like processing endoproteases, furin and PC4, within mouse testis by in situ hybridization. FEBS Lett 316:12-16.
32. Tsuneizumi K, Nakayama T, Kamoshida Y, Kornberg TB, Christian JL, Tabata T. 1997. Daughters against dpp modulates dpp organizing activity in Drosophila wing development. Nature 389:627-631.
33. Wickens M. 1990. In the beginning is the end: regulation of poly(A) addition and removal during early development. Trends Biochem Sci 15:320-324.
34. Xiang Y, Molloy SS, Thomas L, Thomas G. 2000. The PC6B cytoplasmic domain contains two acidic clusters that direct sorting to distinct trans-Golgi network/endosomal compartments. Mol Biol Cell 11:1257-1273.
35. Zheng M, Streck RD, Scott RE, Seidah NG, Pintar JE. 1994. The developmental expression in rat of proteases furin, PC1, PC2, and carboxypeptidase E: implications for early maturation of proteolytic processing capacity. J Neurosci 14:4656-4673.
36. Zhou A, Martin S, Lipkind G, LaMendola J, Steiner DF. 1998. Regulatory roles of the P domain of the subtilisin-like prohormone convertases. J Biol Chem 273: 11107-11114.