Interleukin-1β posttranslational processing - Exploration of P2X7 receptor involvement

Drug Development Research

Volumn 53, Issue 2-3, 2001, Pages 83-90

  Perregaux, David G ^a   Labasi, Jeff ^a   Laliberte, Ron ^a   Stam, Ethan ^a   Solle, Mike ^b   Koller, Bev ^b   Griffiths, Richard ^a   Gabel, Christopher A ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Inflammation; Interleukin 1; P2X7 receptor

Indexed keywords

1 [N,O BIS(5 ISOQUINOLINESULFONYL) N METHYLTYROSYL] 4 PHENYLPIPERAZINE; ADENOSINE TRIPHOSPHATE; CASPASE 3; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; NIGERICIN; PURINE P2X RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT;

ANION TRANSPORT; CELL DEATH; CELL STRUCTURE; CELL SWELLING; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG MECHANISM; HUMAN; HUMAN CELL; INFLAMMATION; MACROPHAGE; MONOCYTE; POTASSIUM TRANSPORT; PROTEIN PROCESSING; TRANSLATION REGULATION;

EID: 20644458325     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/ddr.1175     Document Type: Article

References (5)

1. Auron PE, Webb AC, Rosenwasser LJ, Mucci SF, Rich A, Wolff SM, Dinarello CA. 1984. Nucleotide sequence of human monocyte interleukin 1 precursor cDNA. Proc Natl Acad Sci USA 81:7907-7911.
2. 7 ATP receptor. J biol Cheni 274:47:33206-33208.
3. 7 receptor. Br J Pharmacol 124:1314-1320.
4. 7 receptor. J Cell Biol 138:697-708.
5. Dinarello CA. 1996. Biologic basis for interleukin-1 in disease. Blood 87:2095-2147.