Effect of the interaction between paranoxonase 1 and ATP-binding cassette transporter 1 gene polymorphism on serum lipid level

Chinese Journal of Medical Genetics

Volumn 22, Issue 3, 2005, Pages 272-276

  Xiao, Zhi Jie ^a   Zhao, Shui Ping ^a   Nie, Sai ^a   Tan, Li Min ^a   Wu, Jun ^a   Jiang, Bo ^a   Lu, Wei ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

ATP blinding cassette transporter A 1; Genetic polymorphism; Paranoxonase 1; Serum lipid level

Indexed keywords

ABC TRANSPORTER A1; ARYLDIALKYLPHOSPHATASE; GENOMIC DNA; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; TRIACYLGLYCEROL;

ADULT; AGED; ARTICLE; CHINESE; CHOLESTEROL BLOOD LEVEL; ETHNIC GROUP; FEMALE; GENETIC POLYMORPHISM; HUMAN; HUMAN CELL; LIPID METABOLISM; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; TRIACYLGLYCEROL BLOOD LEVEL;

AGED; ARYLDIALKYLPHOSPHATASE; ATP-BINDING CASSETTE TRANSPORTERS; BASE SEQUENCE; FEMALE; GENOTYPE; HUMANS; LIPIDS; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; SEQUENCE ANALYSIS, DNA;

EID: 20644436038     PISSN: 10039406     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Mackness MI, Mackness B, Durrington PN, et al. Paraoxonase: biochemistry, genetics and relationship to plasma lipoproteins. Curr Opin Lipidol, 1996, 7: 69-76.
2. Mackness MI, Mackness B, Durrington PN, et al. Paraoxonase and coronary heart disease. Curr Opin Lipidol, 1998, 9: 319-324.
3. Clee SM, Zwinderman AH, Engert JC, et al. Common genetic variation in abca1 is associated with altered lipoprotein levels and a modified risk for coronary artery disease. Circulation, 2001, 103: 1198-1205.
4. Serrato M, Marian AJ. A variant of human paraoxonase/arylesterase (HUMPONA) gene is a risk factor for coronary artery disease. J Clin Invest, 1995, 96: 3005-3008.
5. Turban S, Fuentes F, Ferlic L, et al. A prospective study of paraoxonase gene Q/R192 polymorphism and severity, progression and regression of coronary atherosclerosis, plasma lipid levels, clinical events and response to fluvastatin. Atherosclerosis, 2001, 154: 633-640.
6. Hermann SM, Blanc H, Poirier O, et al. The Gln/Arg polymorphism of human paraoxonase (PON192) is not related to myocardial infarction in the ECTIM study. Atherosclerosis, 1996, 126: 299-303.
7. Zama T, Murata M, Matsubara Y, et al. A 192Arg variant of the human paraoxonase (HUMPONA) gene polymorphism is associated with an increased risk for coronary artery disease in the Japanese. Arterioscler Thromb Vasc Biol, 1997, 17: 3565-3569.
8. Ko YL, Ko YS, Wang SM, et al. The Gln-Arg 191 polymorphism of the human paraoxonase gene is not associated with the risk of coronary artery disease among Chinese in Taiwan. Atherosclerosis, 1998, 141: 259-264.
9. Srinivasan SR, Li S, Chen W, et al. R219K polymorphism of the ABCA1 gene and its modulation of the variations in serum high-density lipoprotein cholesterol and triglycerides related to age and adiposity in white versus black young adults. The Bogalusa heart study. Metalolism, 2003, 52: 930-934.
10. Evans D, Beil FU. The association of the R219K polymorphism in the ATP-binding cassette transporter 1 (ABCA1) gene with coronary heart disease and hyperlipidaemia. J Mol Med, 2003, 81: 264-270.
11. Getz GS, Reardon CA. Paraoxonase, a cardioprotective enzyme: continuing issues. Curr Opin Lipidol, 2004, 15: 261-267.
12. Panagotopulos SE, Witting SR, Horace EM, et al. The role of apolipoprotein A-I helix 10 in apolipoprotein-mediated cholesterol efflux via the ATP-binding cassette transporter ABCA1. J Biol Chem, 2002, 277: 39477-39484.
13. Arakawa R, Yokoyama S. Helical apolipoproteins stabilize ATP-binding cassette transporter A1 by protecting it from thiol protease-mediated degradation. J Biol Chem, 2002, 277: 22426-22429.
14. Chroni A, Liu T, Fitzgerald ML, et al. Cross-linking and lipid efflux properties of apoA-I mutants suggest direct association between apoA-I helices and ABCA1. Biochemistry, 2004, 43: 2126-2139.