GABAB receptor 1 polymorphism (G1465A) and temporal lobe epilepsy

Epilepsia

Volumn 46, Issue 6, 2005, Pages 931-933

  Salzmann, Annick ^a   Moulard, Bruno ^a   Crespel, Arielle ^b   Baldy Moulinier, Michel ^b   Buresi, Catherine ^a   Malafosse, Alain ^a,c  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^b MONTPELLIER UNIVERSITY HOSPITAL   (France)

^c Clinique de Belle Idee   (Switzerland)

Author keywords

Association study; GABAB receptor; Genetics; Temporal lobe epilepsy

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR 1; UNCLASSIFIED DRUG; GABA TYPE B RECEPTOR, SUBUNIT 1;

ADOLESCENT; ADULT; ARTICLE; CONTROLLED STUDY; EXON; FEMALE; FRANCE; GABA B GENE; GENETIC CODE; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RECEPTOR GENE; TEMPORAL LOBE EPILEPSY; COMPARATIVE STUDY; GENE FREQUENCY; GENETIC MARKER; GENETIC PREDISPOSITION; GENETIC VARIABILITY; GENETICS; ONSET AGE; PHENOTYPE; REPRODUCIBILITY;

ADOLESCENT; ADULT; AGE OF ONSET; EPILEPSY, TEMPORAL LOBE; EXONS; FEMALE; GENE FREQUENCY; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; PHENOTYPE; POLYMORPHISM, GENETIC; RECEPTORS, GABA-B; REPRODUCIBILITY OF RESULTS; VARIATION (GENETICS);

EID: 20544469352     PISSN: 00139580     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2005.40304.x     Document Type: Article

References (5)

1. Ottman R. Genetics of the partial epilepsies: a review. Epilepsia 1989;30:107-11.
2. Cardon LR, Bell JI. Association study designs for complex diseases. Nat Rev Genet 2001;2:91-9.
3. B2 mRNA variants expression in hippocampus resected from patients with temporal lobe epilepsy. Neuroscience 2003;122:975-84
4. Gambardella A, Manna I, Labate A, et al. GABA(B) receptor 1 polymorphism (G1465A) is associated with temporal lobe epilepsy. Neurology 2003;60:560-3.
5. Lohmueller KE, Pearce CL, Pike M, et al. Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat Genet 2003;33:177-82.