Effects of estrogen on muscarinic acetylcholine receptors in the rat hippocampus

Neuroendocrinology

Volumn 80, Issue 6, 2004, Pages 379-386

  Cardoso, Camila C ^a   Pereira, Renato T S ^a   Koyama, Cristiane A ^b   Porto, Catarina S ^b   Abdalla, Fernando M F ^a,c  

^a INSTITUTO BUTANTAN   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c NONE   (Brazil)

Author keywords

Acetylcholine receptors; Gonadal steroids; Hippocampus; Ovariectomy

Indexed keywords

ESTRADIOL; ESTROGEN; MUSCARINIC RECEPTOR; QUINUCLIDINYL BENZILATE; TRITIUM;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ESTRADIOL BLOOD LEVEL; FEMALE; HIPPOCAMPUS; MEASUREMENT; MONITORING; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; PROESTRUS; PROTEIN EXPRESSION; RAT; RECEPTOR BINDING; TIME; UTERUS WEIGHT; ANIMAL; BIOSYNTHESIS; DRUG EFFECT; METABOLISM;

ANIMALS; ESTROGENS; FEMALE; HIPPOCAMPUS; OVARIECTOMY; RATS; RECEPTORS, MUSCARINIC;

EID: 20544463007     PISSN: 00283835     EISSN: None     Source Type: Journal    
DOI: 10.1159/000084202     Document Type: Article

References (53)

1. Segal M, Auerbach JM: Muscarinic receptors in hippocampal plasticity. Life Sci 1997;60:1085-1091.
2. Rouse ST, Levey AI: Expression of m1-m4 muscarinic acetylcholine receptor immunoreactivity in septo-hippocampal neurons and other identified hippocampal afferents. J Comp Neurol 1996;375:406-416.
3. Rouse ST, Marino MJ, Potter LT, Conn PJ, Levey AI: Muscarinic receptor subtypes involved in hippocampal circuits. Life Sci 1999;64:501-509.
4. Hulme EC, Birdsall NJM, Buckley NJ: Muscarinic receptor subtypes. Annu Rev Pharmacol Toxicol 1990;30:633-673.
5. Levey AI: Immunological localization of m1-m5 muscarinic acetylcholine receptors in peripheral tissues and brain. Life Sci 1993;52:441-448.
6. Birdsall NJM, Buckley NJ, Caulfield MP, Hammer R, Kilbinger HJ, Lambrecht G, Mutschler E, Nathanson NM, Schwarz RD: Muscarinic acetylcholine receptors; in: The IUPHAR Compendium of Receptor Characterization and Classification. London, IUPHAR Media, 1998, pp 36-45.
7. Caulfield MP, Birdsall NJM: International Union of Pharmacology. XVII. Classification of muscarinic acetylcholine receptors. Pharmacol Rev 1998;50:279-290.
8. Singh M, Meyer EM, Millard WJ, Simpkins JW: Ovarian steroid deprivation in a reversible learning impairment and compromised cholinergic function in female Sprague-Dawley rats. Brain Res 1994;644:305-312.
9. McEwen B, Alves SE: Estrogen actions in the central nervous system. Endocrinol Rev 1999;20:279-307.
10. McEwen B: Estrogen actions throughout the brain. Rec Prog Horm Res 2002;57:357-384.
11. Luine VN: Estradiol increases choline acetyltransferase activity in specific basal forebrain nuclei and projection areas of female rats. Exp Neurol 1985;89:484-490.
12. O'Malley CA, Hautamaki RD, Kelley M, Meyer EM: Effects of ovariectomy and estradiol benzoate on high affinity choline uptake, ACh synthesis, and release from rat cerebral cortical synaptosomes. Brain Res 1987;403:389-392.
13. Wu X, Glinn MA, Ostrowski NL, Su Y, Ni B, Cole HW, Bryant HU, Paul SM: Raloxifene and estradiol benzoate both fully restore hippocampal choline acetyltransferase activity in ovariectomized rats. Brain Res 1999;847:98-104.
14. Gibbs RB: Fluctuations in relative levels of choline acetyltransferase mRNA in different regions of the rat basal forebrain across the estrous cycle: Effects of estrogen and progesterone. J Neurosci 1996;16:1049-1055.
15. Van Huizen F, March D, Cynader MS, Shaw C: Muscarinic receptor characteristics and regulation in rat cerebral cortex: Changes during development, aging and the oestrous cycle. Eur J Neurosci 1994;6:237-243.
16. Dohanich GP, Witcher JA, Weaver DR, Clemens LG: Alteration of muscarinic binding in specific brain areas following estrogen treatment. Brain Res 1982;241:347-350.
17. 4 receptor subtype in the rat brain. Brain Res 2002;948:131-137.
18. Vaucher E, Reymond I, Najaffe R, Kar S, Quirion R, Miller MM, Franklin KBJ: Estrogen effects on object memory and cholinergic receptors in young and old female mice. Neurobiol Aging 2002;23:87-95.
19. Everett JW: Progesterone and estrogen in the experimental control of ovulation time and other features of the estrous cycle in the rat. Endocrinology 1948;43:389-405.
20. Maróstica E, Quaze EF, Avellar MCW, Porto CS: Characterization of muscarinic acetylcholine receptors in rat epididymis. Biol Reprod 2001;65:1120-1126.
21. Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-254.
22. Munson PJ, Rodbard D: Ligand: a versatile computerized approach for characterization of ligand-binding system. Anal Biochem 1980;107:220-239.
23. Snedecor GW, Cochran WG: One-way classifications. Analysis of variance; in Snedecor GW, Cochran WG (eds): Statistical Methods, ed 7. Ames, Iowa State University Press, 1980, pp 89-233.
24. Avissar S, Egozi Y, Sokolovsky M: Studies on muscarinic receptors in mouse and rat hypothalamus: A comparison of sex and cyclical differences. Neuroendocrinology 1981;32:295-302.
25. Shughrue PJ, Lane MV, Merchenthaler I: Comparative distribution of estrogen receptor-α and -β mRNA in the rat central nervous system. J Comp Neurol 1997;388:507-525.
26. Li X, Schwartz PE, Rissman EF: Distribution of estrogen receptor-β-like immunoreactivity in rat forebrain. Neuroendocrinology 1997;66:63-67.
27. Shughrue PJ, Merchenthaler I: Evidence for novel estrogen binding sites in the rat hippocampus. Neuroscience 2000;99:605-612.
28. Bulloch K, Brake WG, Lee SJ, Patel A, Wolf OT, McEwen BS: Estrogen increases synaptic protein immunoreactivity in the dorsal and ventral hippocampus of ovariectomized rats. Abstr Soc Neurosci 2000;26:4.
29. Solum DT, Handa RJ: Localization of estrogen receptor alpha (ERα) in pyramidal neurons of the developing rat hippocampus. Dev Brain Res 2001;128:165-175.
30. Hösli E, Hösli L: Cellular localization of estrogen receptors on neurones in various regions of cultured rat CNS: coexistence with cholinergic and galanin receptors. Int J Dev Neurosci 1999;17:317-330.
31. Woolley CS, McEwen BS: Estradiol mediates fluctuation in hippocampal synapse density during the estrus cycle in the adult rat. J Neurosci 1992;12:2549-2554.
32. Murphy DD, Segal M: Regulation of dendritic spine density in cultured rat hippocampal neurons by steroid hormones. J Neurosci 1996;16:4059-4068.
33. Gibbs RB: Effects of estrogen on basal forebrain cholinergic neurons vary as a function of dose and duration of treatment. Brain Res 1997;757:10-16.
34. Gibbs RB: Impairment of basal forebrain cholinergic neurons associated with aging and long-term loss of ovarian function. Exp Neurol 1998;151:289-302.
35. Gibbs RB: Long-term treatment with estrogen and progesterone enhances acquisition of a spatial memory task by ovariectomized aged rats. Neurobiol Aging 2000;21:107-116.
36. 3 muscarinic receptor: role of carboxyl terminal receptor domains in selectivity of ligand binding and coupling to phosphoinositide hydrolysis. Mol Pharmacol 1990;38:872-877.
37. Brown JH, Taylor P: Muscarinic receptor agonists and antagonists; in Hardman JG, Limbird LE (eds): The Pharmacological Basis of Therapeutics, ed 9. New York, McGraw-Hill, 1996, pp 141-160.
38. Brady AE, Limbird LE: G protein-coupled interacting proteins: Emerging roles in localization and signal transduction. Cell Signalling 2002;14:297-309.
39. Hur EM, Kim KT: G protein-coupled signalling and cross-talk achieving rapidity and specificity. Cell Signalling 2002;14:397-405.
40. Rios CD, Jordan BA, Gomes I, Devi LA: G protein-coupled receptor dimerization: Modulation of receptor function. Pharmacol Ther 2001;92:71-87.
41. Zeng FY, Wess J: Molecular aspects of muscarinic receptor dimerization. Neuropsychopharmacology 2000;23:S19-S31.
42. Mitsushima D, Masuda J, Kimura F: Sex differences in the stress-induced release of acetylcholine in the hippocampus and corticosterone from the adrenal cortex in rats. Neuroendocrinology 2003;78:234-240.
43. Gibbs RB: Levels of trkA and BDNF mRNA, but not NGF mRNA, fluctuate across the estrous cycle and increase in response to acute hormone replacement. Brain Res 1998;787:259-268.
44. Zhou Y, Shughrue PJ, Dorsa DM: Estrogen receptor protein is differentially regulated in the preoptic area of the brain and in the uterus during the rat estrous cycle. Neuroendocrinology 1995;61:276-283.
45. Simpkins JW, Green PS, Gridley KE, Singh M, de Fiebre NC, Rajakumar G: Role of estrogen replacement therapy in memory enhancement and the prevention of neuronal loss associated with Alzheimer's disease. Am J Med 1997;103:19S-25S.
46. Wess J: Muscarinic acetylcholine receptor knockout mice: novel phenotypes and clinical implications. Annu Rev Pharmacol Toxicol 2004;44:423-450.
47. Eva C, Fusco M, Bono C, Tria MA, Ricci GS, Eon A, Genazzani E: Nerve growth factor modulates the expression of muscarinic cholinergic receptor messenger RNA in telencephalic neuronal cultures from newborn rat brain. Brain Res 1992;14:344-351.
48. Rosoff ML, Wei J, Nathanson NM: Isolation and characterization of the chicken m2 acetylcholine receptor promoter region: Induction of gene transcription by leukemia inhibitory factor and ciliary neurotrophic factor. Proc Natl Acad Sci USA 1996;93:14889-14894.
49. Wood IC, Roopra A, Buckley NJ: Neural specific expression of the m4 muscarinic acetylcholine receptor gene is mediated by a RE1/ NRSE-type silencing element. J Biol Chem 1996;271:14221-14225.
50. Pepitoni S, Wood IC, Buckley NJ: Structure of the m1 muscarinic acetylcholine receptor gene and its promoter. J Biol Chem 1997;272:17112-17117.
51. Forsythe SM, Kogut PC, Mcconville FUY, Mccauley JA, Halayko AJ, Liu HW, Kao A, Fernandes DJ, Bellam S, Fuchs E, Sinha S, Bell GI, Camoretti-Mercado B, Solway J: Structure and transcription of the human m3 muscarinic receptor gene. Am J Resp Cell Mol Biol 2002;26:298-305.
52. Watters JJ, Dorsa DM: Transcriptional effects of estrogen on neuronal neurotensin gene expression involve cAMP/protein kinase A-dependent signaling mechanisms. J Neurosci 1998;18:6672-6680.
53. 3-muscarinic acetylcholine receptors in the rat myometrium. Mol Cell Endocrinol 2000;160:17-24.