Parallel expression of αIIβ3 and αvβ3 integrins in human melanoma cells upregulates bFGF expression and promotes their angiogenic phenotype

International Journal of Cancer

Volumn 116, Issue 1, 2005, Pages 27-35

  Döme, Balázs ^a   Rásó, Erzsébet ^a   Dobos, Judit ^a   Mészáros, Livia ^a   Varga, Norbert ^a   Puskás, László G ^b   Fehér, László Z ^b   Lörincz, Tamár ^a   Ladányi, Andrea ^a   Trikha, Mohit ^c   Honn, Kenneth V ^c   T́imár, József ^a  

^a NATIONAL INSTITUTE OF ONCOLOGY   (Hungary)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^c WAYNE STATE UNIVERSITY   (United States)

Author keywords

3 integrins; bFGF; Human melanoma; Vascularization; Xenograft

Indexed keywords

BETA3 INTEGRIN; CD34 ANTIGEN; ENDONEXIN; ENDOTHELIN B RECEPTOR; FIBROBLAST GROWTH FACTOR; INTEGRIN ALPHA2 BETA3; PROSTACYCLIN SYNTHASE; PROTEIN TYROSINE KINASE INHIBITOR; UNCLASSIFIED DRUG; VASCULOTROPIN; VITRONECTIN RECEPTOR; FIBRINOGEN RECEPTOR; FIBROBLAST GROWTH FACTOR 2;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CLONE; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MELANOMA CELL; MORPHOMETRICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR VASCULARIZATION; UPREGULATION; ANIMAL; GENE EXPRESSION PROFILING; GENETIC TRANSFECTION; GENETICS; MELANOMA; METABOLISM; MOUSE MUTANT; NEOVASCULARIZATION (PATHOLOGY);

ANIMALS; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION PROFILING; HUMANS; INTEGRIN ALPHAVBETA3; MELANOMA; MICE; MICE, SCID; NEOVASCULARIZATION, PATHOLOGIC; PHENOTYPE; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 20444501809     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.20991     Document Type: Article

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