1H and 13C NMR data to aid the identification and quantification of residual solvents by NMR spectroscopy

Magnetic Resonance in Chemistry

Volumn 43, Issue 6, 2005, Pages 497-509

  Jones, Ian C ^a   Sharman, Gary J ^a,b   Pidgeon, Julia ^a,c  

^a ASTRAZENECA   (United Kingdom)

^b ELI LILLY AND COMPANY   (United States)

^c TRINITY COLLEGE   (United Kingdom)

Author keywords

13C NMR; 1H NMR; International Committee for Harmonization; NMR; Quantification; Residual solvents

Indexed keywords

SOLVENTS; WEBSITES;

13C NMR; 1H NMR; HARMONISATION; INTERNATIONAL COMMITTEE FOR HARMONIZATION; JAVASCRIPT; NMR DATA; NMR-SPECTROSCOPY; QUANTIFICATION; REFERENCE DATA; RESIDUAL SOLVENTS;

NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

SOLVENT; CARBON; PROTON;

ANALYTIC METHOD; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DATA ANALYSIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ANALYSIS; REFERENCE VALUE; CHEMISTRY; CONFORMATION; METHODOLOGY; STANDARD;

CARBON ISOTOPES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; PROTONS; REFERENCE STANDARDS; SOLVENTS;

EID: 20444498108     PISSN: 07491581     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrc.1578     Document Type: Article

References (3)

1. International Committee for Harmonization. ICH Harmonized Tripartite Guideline Q3C. Impurities: guidelines for residual solvents. International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use, 1997.
2. Griffiths L, Irving AM. Analyst 1998; 123: 1061.
3. Gottlieb H, Kotlyar V, Nudelman A. J. Org. Chem. 1997; 62: 7512.