Functional role of RXRs and PPARγ in mature adipocytes

Prostaglandins Leukotrienes and Essential Fatty Acids

Volumn 73, Issue 1 SPEC. ISS., 2005, Pages 51-58

  Metzger, D ^a,b   Imai, T ^a,b   Jiang, M ^a   Takukawa, R ^a   Desvergne, B ^c   Wahli, W ^c   Chambon, P ^a,b  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b INSTITUT CLINIQUE DE LA SOURIS   (France)

^c UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RETINOID X RECEPTOR; RETINOID X RECEPTOR ALPHA; RETINOID X RECEPTOR GAMMA;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; CELL DIFFERENTIATION; CELL FUNCTION; CONFERENCE PAPER; CONTROLLED STUDY; DIET; FETUS; LIPOGENESIS; MOUSE; NEWBORN; NONHUMAN; OBESITY; PRIORITY JOURNAL;

EID: 20444496179     PISSN: 09523278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.plefa.2005.04.007     Document Type: Conference Paper

References (25)

1. B.M. Spiegelman, and J.S. Flier Adipogenesis and obesity: rounding out the big picture Cell 87 1996 377 389
2. S. Mandrup, and M.D. Lane Regulating adipogenesis J. Biol. Chem. 272 1997 5367 5370
3. B. Desvergne, and W. Wahli Peroxisome proliferator-activated receptors: nuclear control of metabolism Endocr. Rev. 20 1999 649 688
4. D.J. Mangelsdorf, C. Thummel, M. Beato, P. Herrlich, G. Schutz, K. Umesono, B. Blumberg, P. Kastner, M. Mark, and P. Chambon The nuclear receptor superfamily: the second decade Cell 83 1995 835 839
5. P. Chambon A decade of molecular biology of retinoic acid receptors FASEB J. 10 1996 940 954
6. E.D. Rosen, C.J. Walkey, P. Puigserver, and B.M. Spiegelman Transcriptional regulation of adipogenesis Genes Dev. 14 2000 1293 1307
7. T. Kadowaki Insights into insulin resistance and type 2 diabetes from knockout mouse models J. Clin. Invest. 106 2000 459 465
8. C.H. Lee, P. Olson, and R.M. Evans Minireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors Endocrinology 144 2003 2201 2207
9. P. Kastner, J.M. Grondona, M. Mark, A. Gansmuller, M. LeMeur, D. Decimo, J.L. Vonesch, P. Dolle, and P. Chambon Genetic analysis of RXR alpha developmental function: convergence of RXR and RAR signaling pathways in heart and eye morphogenesis Cell 78 1994 987 1003
10. H.M. Sucov, E. Dyson, C.L. Gumeringer, J. Price, K.R. Chien, and R.M. Evans RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis Genes Dev. 8 1994 1007 1018
11. T. Imai, M. Jiang, P. Chambon, and D. Metzger Impaired adipogenesis and lipolysis in the mouse upon selective ablation of the retinoid X receptor alpha mediated by a tamoxifen-inducible chimeric Cre recombinase (Cre-ERT2) in adipocytes Proc. Natl. Acad. Sci. USA 98 2001 224 228
12. S.R. Ross, R.A. Graves, and B.M. Spiegelman Targeted expression of a toxin gene to adipose tissue: transgenic mice resistant to obesity Genes Dev. 7 1993 1318 1324
13. J.W. Olney Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate Science 164 1969 719 721
14. W.J. Pizzi, and J.E. Barnhart Effects of monosodium glutamate on somatic development, obesity and activity in the mouse Pharmacol. Biochem. Behav. 5 1976 551 557
15. C.M. Smas, and H.S. Sul Pref-1, a protein containing EGF-like repeats, inhibits adipocyte differentiation Cell 73 1993 725 734
16. C.M. Smas, L. Chen, and H.S. Sul Cleavage of membrane-associated pref-1 generates a soluble inhibitor of adipocyte differentiation Mol. Cell Biol. 17 1997 977 988
17. T. Imai, R. Takakuwa, S. Marchand, E. Dentz, J.M. Bornert, N. Messaddeq, O. Wendling, M. Mark, B. Desvergne, W. Wahli, P. Chambon, and D. Metzger Peroxisome proliferator-activated receptor gamma is required in mature white and brown adipocytes for their survival in the mouse Proc. Natl. Acad. Sci. USA 101 2004 4543 4547
18. S. Cinti, The Adipose Organ, 1999.
19. W. He, Y. Barak, A. Hevener, P. Olson, D. Liao, J. Le, M. Nelson, E. Ong, J.M. Olefsky, and R.M. Evans Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle Proc. Natl. Acad. Sci. USA 2003
20. P. Kastner, M. Mark, M. Leid, A. Gansmuller, W. Chin, J.M. Grondona, D. Decimo, W. Krezel, A. Dierich, and P. Chambon Abnormal spermatogenesis in RXR beta mutant mice Genes Dev. 10 1996 80 92
21. W. Krezel, V. Dupe, M. Mark, A. Dierich, P. Kastner, and P. Chambon RXR gamma null mice are apparently normal and compound RXR alpha +/-/RXR beta -/-/RXR gamma -/- mutant mice are viable Proc. Natl. Acad. Sci. USA 93 1996 9010 9014
22. N. Kubota, Y. Terauchi, H. Miki, H. Tamemoto, T. Yamauchi, K. Komeda, S. Satoh, R. Nakano, C. Ishii, T. Sugiyama, K. Eto, Y. Tsubamoto, A. Okuno, K. Murakami, H. Sekihara, G. Hasegawa, M. Naito, Y. Toyoshima, S. Tanaka, K. Shiota, T. Kitamura, T. Fujita, O. Ezaki, S. Aizawa, and T. Kadowaki PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance Mol. Cell 4 1999 597 609
23. J. Rieusset, F. Touri, L. Michalik, P. Escher, B. Desvergne, E. Niesor, and W. Wahli A new selective peroxisome proliferator-activated receptor gamma antagonist with antiobesity and antidiabetic activity Mol. Endocrinol. 16 2002 2628 2644
24. T. Yamauchi, H. Waki, J. Kamon, K. Murakami, K. Motojima, K. Komeda, H. Miki, N. Kubota, Y. Terauchi, A. Tsuchida, N. Tsuboyama-Kasaoka, N. Yamauchi, T. Ide, W. Hori, S. Kato, M. Fukayama, Y. Akanuma, O. Ezaki, A. Itai, R. Nagai, S. Kimura, K. Tobe, H. Kagechika, K. Shudo, and T. Kadowaki Inhibition of RXR and PPARgamma ameliorates diet-induced obesity and type 2 diabetes J. Clin. Invest. 108 2001 1001 1013
25. N. Kawaguchi, K. Toriyama, E. Nicodemou-Lena, K. Inou, S. Torii, and Y. Kitagawa De novo adipogenesis in mice at the site of injection of basement membrane and basic fibroblast growth factor Proc. Natl. Acad. Sci. USA 95 1998 1062 1066