Inhibition of rat brain mitochondrial electron transport chain activity by dopamine oxidation products during extended in vitro incubation: Implications for Parkinson's disease

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1741, Issue 1-2, 2005, Pages 65-74

  Khan, Firoj Hossain ^a,c   Sen, Tanusree ^a   Maiti, Arpan Kumar ^a   Jana, Sirsendu ^a   Chatterjee, Uttara ^b   Chakrabarti, Sasanka ^a  

^a BC Roy Postgraduate Institute of Basic Medical Sciences   (India)

^b Dr BC Roy Post graduate Institute of Basic Medical Sciences IPGMER   (India)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Dopamine; Electron transport chain; Mitochondria; Oxygen radicals; Parkinson's disease; Quinones

Indexed keywords

BROMINE DERIVATIVE; CATALASE; CYTOCHROME C OXIDASE; DIMETHYL SULFOXIDE; DOPAMINE; GLUTATHIONE; HYDROXIDE; MANNITOL; MONOPHENOL MONOOXYGENASE; PENTETIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINIC ACID;

ANIMAL TISSUE; ARTICLE; BRAIN MITOCHONDRION; DOPAMINE METABOLISM; ELECTRON TRANSPORT; ENZYME INHIBITION; IN VITRO STUDY; INCUBATION TIME; INHIBITION KINETICS; LYSIS; NONHUMAN; OXIDATION; PARKINSON DISEASE; PRIORITY JOURNAL; RAT;

ANIMALS; BRAIN; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRON TRANSPORT COMPLEX I; ELECTRON TRANSPORT COMPLEX IV; HYDROGEN-ION CONCENTRATION; MITOCHONDRIA; OXIDATION-REDUCTION; PARKINSON DISEASE; QUINONES; RATS; RATS, INBRED STRAINS; REACTIVE OXYGEN SPECIES; TIME FACTORS;

EID: 20444491283     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2005.03.013     Document Type: Article

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