Tetramethylenedisulfotetramine: Old agent and new terror

Annals of Emergency Medicine

Volumn 45, Issue 6, 2005, Pages 609-613

  Whitlow, K Scott ^a,b,c,f   Belson, Martin ^a,c   Barrueto, Fermin ^d   Nelson, Lewis ^e   Henderson, Alden K ^a  

^a NATIONAL CENTER FOR ENVIRONMENTAL HEALTH   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c GRADY HEALTH SYSTEM   (United States)

^d UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^e NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED CARBON; ANTIDOTE; BARBITURIC ACID DERIVATIVE; BENZODIAZEPINE; PESTICIDE; PICROTOXIN; POISON; PYRIDOXINE; RODENTICIDE; TETRAMETHYLENEDISULFOTETRAMINE; UNCLASSIFIED DRUG; UNITHIOL;

BRAIN INJURY; CHELATION THERAPY; CHINA; CLINICAL FEATURE; DRUG APPROVAL; EPILEPTIC STATE; EXPOSURE; FOOD CONTAMINATION; HUMAN; INGESTION; INTOXICATION; LABORATORY TEST; LETHAL DOSE; LETHALITY; MENTAL HEALTH; NEUROTOXICITY; NONHUMAN; OCCUPATIONAL EXPOSURE; PRIORITY JOURNAL; PUBLIC HEALTH; REVIEW; SEIZURE;

ANIMALS; BRIDGED COMPOUNDS; ENVIRONMENTAL EXPOSURE; HUMANS; LETHAL DOSE 50; MICE; NEUROTOXINS; PESTICIDES; POISONING; SEIZURES; TERRORISM;

EID: 20444444344     PISSN: 01960644     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.annemergmed.2004.09.009     Document Type: Review

References (34)

1. L.S. Nelson, R.S. Hoffman, and R. Rao Poisoning associated with illegal use of aldicarb as a rodenticide: New York City 1994-1997 MMWR Morb Mortal Wkly Rep 46 1997 961 963
2. L.S. Nelson, J. Perrone, and F. DeRoos Aldicarb poisoning by an illicit rodenticide imported into the United States: Tres Pasitos J Toxicol Clin Toxicol 39 2001 447 452
3. F. Barrueto, L.S. Nelson, and R.S. Hoffman Poisoning by an illegally imported Chinese rodenticide containing tetramethylenedisulfotetramine: New York City, 2002 MMWR Morb Mortal Wkly Rep 52 2003 199 200
4. Eckholm E. Man admits poisoning food in rival's shop, killing 38 in China [New York Times online]. Available at: http://query.nytimes.com/gst/abstract. html?res=F40E11FE3E540C7B8DDDA00894DA404482. Accessed April 7, 2004.
5. 70 Children hospitalized for poisoning in southeast China. Beijing, China, Nov. 26, 2002 [People's Daily Online]. Available at: http://english. peopledaily.com.cn/200211/26/eng20021126_107505.shtml. Accessed April 7, 2004.
6. 61 Students felled by rat poison in central China. Beijing, China. 2003-09-29 [China View Web site]. Available at: http://news.xinhuanet.com/ english/2003-09/29/content_1106140.htm. Accessed April 7, 2004.
7. T.M.S. Reid, I.M. Gould, and I.M. Mackie Food poisoning due to the consumption of red whelks Epidemiol Infect 101 1988 419-242
8. A.J. Power, B.F. Keegan, and K. Nolan The seasonality and role of the neurotoxin tetramine in the salivary glands of the red whelk Neptunea antiqua (L.) Toxicon 40 2002 419 425
9. CFETP, Chinese Field Epidemiology Training Program. Summary of tetramethylenedisulfotetramine (tetramine) rodenticide toxicity and treatment issues in humans, China [CFETP].
10. Yardley J. Rat poison: murder weapon of choice in rural China [Free Republic Web site]. Available at: http://209.157.64.200/focus/f-news/1023299/ posts. Accessed June 13, 2004.
11. F.Y. Guan, Y.T. Liu, and Y. Liu GC/MS identification of tetramine in samples from human alimentary intoxication and evaluation of artificial carbonic kidneys for the treatment of the victims J Anal Toxicol 17 1993 199 201
12. Food poisoning at wedding kills one, makes 24 ill [China View Web site]. Available at: http://news.xinhuanet.com/english/2003-11/14/content_1179518.htm. Accessed June 13, 2004.
13. 76 College students poisoned in Guangxi [China View Web site]. Available at: http://news.xinhuanet.com/english/2003-12/02/content_1208201.htm. Accessed on June 13, 2004.
14. 74 Down by poisoned food in Shaanxi [China View Web site]. Available at: http://news.xinhuanet.com/english/2004-04/15/content_1421657.htm. Accessed June 13, 2004.
15. T. Esser, A.E. Karu, and R.F. Toia Recognition of tetramethylenedisulfotetramine and related sulfamides by the brain GABA-gated chloride channel and cyclodiene-sensitive monoclonal antibody Chem Res Toxicol 4 1991 162 167
16. J.E. Casida, and C.J. Palmer 2,6,7-Trioxabicyclo(2.2.2) octanes: chemistry, toxicology, and action at the GABA-gated chloride channel Adv Biochem Psychopharmacol 45 1988 109 123
17. R.J. Brennan, J.F. Waeckerle, and T.W. Sharp Chemical warfare agents: medical and emergency public health issues Ann Emerg Med 34 1999 191 204
18. TOXINZ Database. National Poisons Centre, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.
19. International Program on Chemical Safety. The World Health Organization recommended classification of pesticides by hazard guidelines to classification 2000-2002 [World Health Organization Web site]. Available at: http://www.who.int/pcs/docs/Classif_Pestic_2000-02.pdf. Accessed April 7, 2004.
20. Ministry of Environment and Forests Web site. Environment Protection Act of 1996. Schedule 2. Available at: http://envfor.nic.in/legis/hsm/gsr347-sh3. doc. Accessed April 22, 2004.
21. Y. Zhou, L. Liu, and L. Tang An autopsy analysis on 5 cases of poisoning with tetramethylenedisulfotetramine J Forensic Med 14 1998 214 215 217, 252
22. S. Jing, Z.-S. Yu, and J.-Z. Zhao Determination of tetramine in postmortem specimens by GC-NPD J Anal Toxicol 18 1994 275 277
23. L. Junting, F. Chuichang, and W. Guohua Editorial letter J Forensic Sci 38 1993 236 238
24. J. Mo, and C. His-Yuan Synthesis of tetramethylenetetramine disulfone Yao Hsueh T'ung Pao 7 1959 395
25. E.J. Gallagher Neurologic principles L. Goldfrank N. Flomenbaum N. Lewin Goldfrank's Toxicologic Emergencies 7th ed. 2002 McGraw Hill New York, NY
26. 6 and sodium dimercaptopropane sulfonate on acute poisoning with tetramethylenedisulfotetramine in animals Zhonghua Nei Ke Za Zhi 41 2002 186 188
27. US Army Soldier and Biological Chemical Command. Guidelines for Mass Casualty Decontamination During a Terrorist Chemical Agent Incident. Aberdeen Proving Ground, MD: Department of the Army, US Army Soldier and Biological Chemical Command (SBCCOM); 2000:4-9.
28. C.Y. Zhang, T.J. Zhu, and G.X. Hu Effect of sodium dimercaptopropanesulfonate on antagonism of tetramethylenedisulfotetramine to GABA receptor Acta Pharmacol Sin 22 2001 435 439
29. B.Y. Ying, X. Fan, and S.Q. Zhang Observation of therapeutic effects on Na-DMPS in antidotal treatment of acute tetramine poisoning Chin J Intern Med 59 2000 767 768
30. J.X. Fu, Y. Zong, and G.R. Qin Advances in diagnosis and treatment of poisoning by rodenticides Chin J Crit Care Med 22 2002 59 61
31. 6 to rescue acute tetramine poisoning in 13 cases Jiujiang Med J 15 2001 179
32. A.S. Khan, D.L. Swerdlow, and D.D. Juranek Precaution against biological and chemical terrorism directed at food and water supplies Public Health Rep 16 2001 3 14
33. M. Boulton, M. Stanbury, and D. Wade Nicotine poisoning after ingestion of contaminated ground beef - Michigan, 2003 MMWR Morb Mortal Wkly Rep 52 2003 413 416
34. T.L. Litovitz, W. Klein-Schwartz, and G.C. Rodgers 2001 Annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System Am J Emerg Med 20 2002 434 435