Reflex-mediated enhancement of airway protective mechanisms

American Journal of Medicine

Volumn 108, Issue 4 SUPPL. 1, 2000, Pages 8-14

  Shaker, Reza ^a   Hogan, Walter J ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AIRWAY; ASPIRATION; ASPIRATION PNEUMONIA; CONFERENCE PAPER; ESOPHAGUS DILATATION; GASTROESOPHAGEAL REFLUX; GLOTTIS; HUMAN; LARYNX; LOWER ESOPHAGUS SPHINCTER; PERISTALSIS; PHARYNX; PRESSURE; PRIORITY JOURNAL; PROTECTION; REFLEX; SMOOTH MUSCLE CONTRACTILITY; STOMACH CONTENT; SWALLOWING; UPPER ESOPHAGUS SPHINCTER;

DEGLUTITION; ESOPHAGUS; GASTROESOPHAGEAL REFLUX; GLOTTIS; HUMANS; INHALATION; MUSCLE CONTRACTION; PHARYNX; REFLEX;

EID: 0034611208     PISSN: 00029343     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9343(99)00289-2     Document Type: Conference Paper

References (46)

1. Hunt P.S., Connell A.M., Smiley T.B. The cricopharyngeal sphincter in gastric reflux. Gut. 11:1970;303-306.
2. Gerhardt D.C., Shuck T.J., Bordeau R.A., Winship D.H. Human upper esophageal sphincter response to volume, osmotic and acid stimuli . Gastroenterology. 75:1978;268-274.
3. Fyke F.E. Jr, Code C.F. Resting and deglutition pressure in the pharyngoesophageal region. Gastroenterology. 29:1955;24-34.
4. Palmer E.D. Disorders of the cricopharyngeus muscle a review . Gastroenterology. 71:1976;510-519.
5. Kilman W.J., Goyal R.K. Disorders of pharyngeal and upper esophageal sphincter motor function. Arch Intern Med. 136:1976;592-601.
6. Asoh R., Goyal R.K. Manometry and electromyography of the upper esophageal sphincter in the opossum. Gastroenterology. 74:1978;514-520.
7. Kahrilas P.J., Dodds W.J., Dent J., Haeberle B., Hogan W.J., Arndorfer R.C. Effect of sleep, spontaneous gastroesophageal reflux and a meal on upper esophageal sphincter pressure in normal human volunteers. Gastroenterology. 92:1987;466-471.
8. Shaker R, Ren J, Podvrsan B, et al. Effect of aging and bolus variables on pharyngeal and upper esophageal sphincter motor function. Am J Physiol. 1993;264 (Gastrointest Liver Physiol. 27):G427-G432.
9. Freiman J.M., El-Sharkawy T.Y., Diamant N.E. Effect of bilateral vagosympathetic nerve blockade on response of the dog upper esophageal sphincter (UES) to intraesophageal distention and acid. Gastroenterology. 81:1981;78-84.
10. Wallin L., Boesby S., Madsen T. The effect of HC1 infusion in the lower part of the oesophagus on the pharyngo-oesophageal sphincter pressure in normal subjects. Scand J Gastroenterol. 13:1978;821-826.
11. Gerhardt D.C., Shuck T.J., Bordeaux R.A., Winship D.H. Human upper esophageal sphincter. Gastroenterology. 75:1978;268-274.
12. Vakil N., Kahrilas P.J., Dodds W., Vanagunas A. Absence of an upper esophageal sphincter response to acid reflux. Am J Gastroenterol. 84:1989;606-610.
13. Torrico S., Ren J., Sui Z., Hofmann C., Shaker R. Upper esophageal sphincter function during gastroesophageal reflux events. Gastroenterology. 114:1998;G3481.
14. Shaker R., Dodds W.J., Ren J., Hogan W.J., Arndorfer R.C. Esophagoglottal closure reflex a mechanism of airway protection . Gastroenterology. 102:1992;857-861.
15. Shaker R, Ren J, Medda B, Lang I, Cowles V, Jaradeh S. Identification and characterization of the esophagoglottal closure reflex in a feline model. Am J Physiol. 1994; 266 (Gastrointest Liver Physiol. 29):G147-G153.
16. Wright R.A., Miller S.A., Corsello B.F. Acid-induced esophago-bronchial-cardiac reflexes in humans. Gastroenterology. 99:1990;71-73.
17. Shaker R., Dodds W.J., Dantas R.O., Hogan W.J., Arndorfer R. Coordination of deglutitive glottic closure with oropharyngeal swallowing. Gastroenterology. 98:1990;1478-1481.
18. Curtis D.J., Cruess D.F., Dachman A.H., Maso E. Timing in the normal pharyngeal swallow. Invest Radiol. 19:1984;523-529.
19. Sasaki C.T., Isaacson G. Functional anatomy of the larynx. Otolaryngol Clin North Am. 21:1988;595-612.
20. Shaker R., Ren J., Hogan W.J., Liu J., Podvrsan B., Sui Z. Glottal function during postprandial gastroesophageal reflux. Gastroenterology. 104:1993;A581. Abstract.
21. Ren J., Shaker R., Medda B., Bonnevier J., Kern M., Dunn B. Effect of acute esophagitis on the esophagoglottal closure reflex in a feline model. Gastroenterology. 108:1995;A677. Abstract.
22. Paterson W.G., Rattan S., Goyal R.K. Experimental induction of isolated lower esophageal sphincter relaxation in anesthetized opossums. J Clin Invest. 77:1986;1187-1193.
23. Nishino T., Takizawa K., Yokokawa N., Hiraga K. Depression of the swallowing reflex during sedation and/or relative analgesia produced by inhalation of 50% nitrous oxide in oxygen. Anesthesiology. 67:1987;995-998.
24. Nishino T. Swallowing as a protective reflex for the upper respiratory tract. Anesthesiology. 79:1993;588-601.
25. Shaker R., Ren J., Zamir Z., Sarna A., Liu J., Sui Z. Effect of aging, position, and temperature on the threshold volume triggering pharyngeal swallows. Gastroenterology. 107:1994;396-402.
26. Ebihara T., Sekizawa K., Nakazawa H., Sasaki H. Capsaicin and swallowing reflex. Lancet. 341:1993;432.
27. Patterson W.G., Hynna-Liepert T.T., Selucky M. Comparison of primary and secondary esophageal peristalsis in humans effect of atropine . Am J Physiol. 260:1991;G52-G57.
28. Christensen J., Lund G.F. Esophageal responses to distension and electrical stimulation. J Clin Invest. 48:1969;408-419.
29. Paterson WG. Neuromuscular mechanisms of esophageal responses at and proximal to a distending balloon. Am J Physiol. 1991;260(Gastrointest Liver Physiol. 23):G148-G155.
30. Lichter I., Muir R.C. The pattern of swallowing during sleep. Electroencephalogr Clin Neurophysiol. 38:1975;427-432.
31. Lear C.S., Flanagan J.B., Moorrees C.F. The frequency of deglutition in man. Arch Oral Biol. 10:1965;83-100.
32. Hollshwandner G., Brenman H., Friedman M. Role of afferent sensors in the initiation of swallowing in man. J Dent Res. 54:1975;83-88.
33. Pommerenke W. A study of the sensory areas eliciting the swallowing reflex. Am J Physiol. 84:1928;36-41.
34. Storey A. Interactions of alimentary and upper respiratory tract reflexes. In: Sessle BJ, Hannan AG, eds. Mastication and Swallowing. Toronto: University of Toronto Press, 1976:22-36.
35. Dent J., Dodds W.J., Friedman R.H., et al. Mechanism of gastroesophageal reflux in recumbent asymptomatic human subjects. J Clin Invest. 65:1980;256-267.
36. Medda BK, Lang IM, Layman R, Hogan WJ, Dodds WJ, Shaker R. Characterization and quantification of a pharyngo-UES contractile reflex in cats. Am J Physiol. 1994;167(Gastrointest Liver Physiol. 30):G972-G983.
37. Shaker R, Ren J, Xie P, Lang IM, Bardan E, Sui Z. Characterization of the pharyngo-UES contractile reflex in humans. Am J Physiol. 273(Gastrointest Liver Physiol. 36):854-858, 1997.
38. McClure R.C., Dallman M.J., Garrett P.G. Cat Anatomy. 1973;Lea and Febiger, Philadelphia.
39. Barlett D. Upper airway motor systems. Handbook of Physiology. The Respiratory System, vol. 2. Control of Breathing. 1986;363-394 American Physiology Society, Bethesda, MD.
40. Ren J., Shaker R., Lang I., Sui Z. Effect of volume, temperature and anesthesia on the pharyngo-UES contractile reflex in humans. Gastroenterology. 108:1995;A677. Abstract.
41. Ulualp S.O., Toohill R.J., Kern M., Shaker R. Pharyngo-UES contractile reflex in patients with posterior laryngitis. Laryngoscope. 108:1998;1354-1357.
42. Ren J., Shaker R., Dua K., Trifan A., Podvrsan B., Sui Z. Glottal adduction response to pharyngeal water stimulation evidence for a pharyngoglottal closure reflex . Gastroenterology. 106:1994;A558. Abstract.
43. Shaker R, Medda BK, Ren J, Jaradeh S, Xie P, Lang IM. Pharyngoglottal closure reflex: identification and characterization in a feline model. Am J Physiol. 1998;275(Gastrointest Liver Physiol. 38):G521-G525.
44. Shaker R, Ren J, Kern M, Dodds WJ, Hogan WJ, Li Q. Mechanisms of airway protection and UES opening during belching. Am J Physiol. 1992;262(Gastrointest Liver Physiol. 25):G621-G628.
45. Dougherty R.W., Hill K.J., Campeti F.L., McClure R.C., Habel R.E. Studies of pharyngeal and laryngeal activity during eructation in ruminants. Am J Vet Res. 23:1962;213-219.
46. Shaker R., Ulualp S.O., Kannappan A., Narayannan S., Hofmann C. Identification of laryngo-UES contractile reflex in humans. Gastroenterology. 116:1999;A1081. Abstract.