메뉴 건너뛰기




Volumn 11, Issue 6, 2005, Pages 559-566

Tumor necrosis factor α reduces butyrate oxidation in vitro in human colonic mucosa: A link from inflammatory process to mucosal damage?

Author keywords

oxidation; Butyrate; Glucose; Inflammatory bowel disease; Tumor necrosis factor

Indexed keywords

BUTYRIC ACID; CARBON 14; CARBON DIOXIDE; CYTOKINE; GLUCOSE; INTERLEUKIN 1BETA; INTERLEUKIN 6; TRYPAN BLUE; TUMOR NECROSIS FACTOR ALPHA;

EID: 20444440260     PISSN: 10780998     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.MIB.0000161918.04760.f3     Document Type: Article
Times cited : (22)

References (70)
  • 1
    • 0019128183 scopus 로고
    • Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man
    • Roediger WEW. Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man. Gut. 1980;21:793-798.
    • (1980) Gut , vol.21 , pp. 793-798
    • Roediger, W.E.W.1
  • 2
    • 0024562962 scopus 로고
    • Short chain fatty acids stimulate active Na and Cl absorption in vitro in the rat distal colon
    • Binder HJ, Mehta P. Short chain fatty acids stimulate active Na and Cl absorption in vitro in the rat distal colon. Gastroenterology. 1989;96:989-996.
    • (1989) Gastroenterology , vol.96 , pp. 989-996
    • Binder, H.J.1    Mehta, P.2
  • 3
    • 0028796718 scopus 로고
    • Colonic mucin synthesis is increased by butyrate sodium
    • Finnie IA, Dwarakanath AD, Taylor BA, et al. Colonic mucin synthesis is increased by butyrate sodium. Gut. 1995;36:93-99.
    • (1995) Gut , vol.36 , pp. 93-99
    • Finnie, I.A.1    Dwarakanath, A.D.2    Taylor, B.A.3
  • 4
    • 0027083326 scopus 로고
    • Lipogenesis from n-butyrate in colonocytes. Action of reducing agents and 5-amino salicylic acid with relevance to ulcerative colitis
    • Roediger WEW, Kapaniris O, Millard S. Lipogenesis from n-butyrate in colonocytes. Action of reducing agents and 5-amino salicylic acid with relevance to ulcerative colitis. Mol Cell Biochem. 1992;118:113-118.
    • (1992) Mol Cell Biochem , vol.118 , pp. 113-118
    • Roediger, W.E.W.1    Kapaniris, O.2    Millard, S.3
  • 5
    • 0025924523 scopus 로고
    • Impaired sulphation of phenol by the colonic mucosa in quiescent and active ulcerative colitis
    • Ramakrishna BS, Roberts-Thomson IC, Pannall PR, et al. Impaired sulphation of phenol by the colonic mucosa in quiescent and active ulcerative colitis. Gut. 1991;32:46-49.
    • (1991) Gut , vol.32 , pp. 46-49
    • Ramakrishna, B.S.1    Roberts-Thomson, I.C.2    Pannall, P.R.3
  • 6
    • 0028069352 scopus 로고
    • Cytokines in intestinal inflammation: Pathophysiological and clinical considerations
    • Balfour Sartor R. Cytokines in intestinal inflammation: pathophysiological and clinical considerations. Gastroenterology. 1994;106:533-539.
    • (1994) Gastroenterology , vol.106 , pp. 533-539
    • Balfour Sartor, R.1
  • 7
    • 0024822787 scopus 로고
    • Interleukin-1 in the pathogenesis of and protection from inflammatory bowel disease
    • Cominelli F, Dinarello CA. Interleukin-1 in the pathogenesis of and protection from inflammatory bowel disease. Biotherapy. 1989;1:369-375.
    • (1989) Biotherapy , vol.1 , pp. 369-375
    • Cominelli, F.1    Dinarello, C.A.2
  • 8
    • 0026514203 scopus 로고
    • Increased concentrations of interleukin 1β, interleukin-2, and soluble interleukin-2 receptors in endoscopical mucosal biopsy specimens with active inflammatory bowel disease
    • Brynskov J, Tvede N, Andersen CB, et al. Increased concentrations of interleukin 1β, interleukin-2, and soluble interleukin-2 receptors in endoscopical mucosal biopsy specimens with active inflammatory bowel disease. Gut. 1992;33:55-58.
    • (1992) Gut , vol.33 , pp. 55-58
    • Brynskov, J.1    Tvede, N.2    Andersen, C.B.3
  • 9
    • 0025442212 scopus 로고
    • Role of interleukin 1 in inflammatory bowel disease - Enhanced production during active disease
    • Ligumsky M, Simon PL, Karmeli F, et al. Role of interleukin 1 in inflammatory bowel disease - enhanced production during active disease. Gut. 1990;31:686-689.
    • (1990) Gut , vol.31 , pp. 686-689
    • Ligumsky, M.1    Simon, P.L.2    Karmeli, F.3
  • 10
    • 0026336617 scopus 로고
    • Colonic mucosal interleukin-6 in inflammatory bowel disease
    • Mitsuyama K, Sasaki E, Toyonaga A, et al. Colonic mucosal interleukin-6 in inflammatory bowel disease. Digestion. 1991;50:104-111.
    • (1991) Digestion , vol.50 , pp. 104-111
    • Mitsuyama, K.1    Sasaki, E.2    Toyonaga, A.3
  • 11
    • 0029017776 scopus 로고
    • Elevation of interleukin-6 in inflammatory bowel disease is macrophage- and epithelial cell-dependent
    • Kusugami K, Fukatsu A, Tanimoto M, et al. Elevation of interleukin-6 in inflammatory bowel disease is macrophage- and epithelial cell-dependent. Dig Dis Sci. 1995;40:949-959.
    • (1995) Dig Dis Sci , vol.40 , pp. 949-959
    • Kusugami, K.1    Fukatsu, A.2    Tanimoto, M.3
  • 12
    • 0023940797 scopus 로고
    • Bowel necrosis induced by tumor necrosis factor in rats is mediated by platelet-activating factor
    • Sun X, Hsueh W. Bowel necrosis induced by tumor necrosis factor in rats is mediated by platelet-activating factor. J Clin Invest. 1988;81:1328-1331.
    • (1988) J Clin Invest , vol.81 , pp. 1328-1331
    • Sun, X.1    Hsueh, W.2
  • 13
    • 0027357122 scopus 로고
    • Pathophysiologic alterations induced by tumor necrosis factor
    • Remick D, Kunkel S. Pathophysiologic alterations induced by tumor necrosis factor. Int Rev Exp Pathol. 1993;34:7-25.
    • (1993) Int Rev Exp Pathol , vol.34 , pp. 7-25
    • Remick, D.1    Kunkel, S.2
  • 14
    • 0023501870 scopus 로고
    • Development of partial tolerance to the gastrointestinal effects of high doses of recombinant tumor necrosis factor-α in rodents
    • Patton JS, Peters PM, McCabe J, et al. Development of partial tolerance to the gastrointestinal effects of high doses of recombinant tumor necrosis factor-α in rodents. J Clin Invest. 1987;80:1587-1596.
    • (1987) J Clin Invest , vol.80 , pp. 1587-1596
    • Patton, J.S.1    Peters, P.M.2    McCabe, J.3
  • 15
    • 0024374006 scopus 로고
    • Interleukin-1 induced pathophysiology: Induction of cytokine development of histopathologic changes, and immunopharmacologic intervention
    • Butler LD, Layman NK, Cain RL, et al. Interleukin-1 induced pathophysiology: induction of cytokine development of histopathologic changes, and immunopharmacologic intervention. Clin Immunol Immunopathol. 1989;53:400-421.
    • (1989) Clin Immunol Immunopathol , vol.53 , pp. 400-421
    • Butler, L.D.1    Layman, N.K.2    Cain, R.L.3
  • 16
    • 9044236905 scopus 로고    scopus 로고
    • IL-6-induced anaemia in rats: Possible pathogenetic implications for anaemia observed in chronic inflammations
    • Jongen-Lavrencic M, Peeters HRM, Rozemuller H, et al. IL-6-induced anaemia in rats: possible pathogenetic implications for anaemia observed in chronic inflammations. Clin Exp Immunol. 1996;103:328-334.
    • (1996) Clin Exp Immunol , vol.103 , pp. 328-334
    • Jongen-Lavrencic, M.1    Peeters, H.R.M.2    Rozemuller, H.3
  • 17
    • 0018855591 scopus 로고
    • The colonic epithelium in ulcerative colitis: An energy deficiency disease
    • Roediger WEW. The colonic epithelium in ulcerative colitis: an energy deficiency disease. Lancet. 1980;2:712-715.
    • (1980) Lancet , vol.2 , pp. 712-715
    • Roediger, W.E.W.1
  • 18
    • 0031773127 scopus 로고    scopus 로고
    • Mucosal metabolism in ulcerative colitis and Crohn's disease
    • Duffy MM, Regan MC, Ravichandran P, et al. Mucosal metabolism in ulcerative colitis and Crohn's disease. Dis Colon Rectum. 1998;41:1399-1405.
    • (1998) Dis Colon Rectum , vol.41 , pp. 1399-1405
    • Duffy, M.M.1    Regan, M.C.2    Ravichandran, P.3
  • 19
    • 0034104703 scopus 로고    scopus 로고
    • Butyrate and glucose metabolism by colonocytes in experimental colitis in mice
    • Ahmad M, Krishnan S, Ramakrishna B, et al. Butyrate and glucose metabolism by colonocytes in experimental colitis in mice. Gut. 2000;46:493-499.
    • (2000) Gut , vol.46 , pp. 493-499
    • Ahmad, M.1    Krishnan, S.2    Ramakrishna, B.3
  • 20
    • 0031704909 scopus 로고    scopus 로고
    • In vivo butyrate metabolism and colonic permeability in extensive ulcerative colitis
    • Den Hond E, Hiele M, Evenepoet P, et al. In vivo butyrate metabolism and colonic permeability in extensive ulcerative colitis. Gastroenterology. 1998;115:584-590.
    • (1998) Gastroenterology , vol.115 , pp. 584-590
    • Den Hond, E.1    Hiele, M.2    Evenepoet, P.3
  • 21
    • 0034067153 scopus 로고    scopus 로고
    • In vivo measurement of colonic butyrate metabolism in patients with quiescent ulcerative colitis
    • Simpson EJ, Chapman MAS, Dawson J, et al. In vivo measurement of colonic butyrate metabolism in patients with quiescent ulcerative colitis. Gut. 2000;46:73-77.
    • (2000) Gut , vol.46 , pp. 73-77
    • Simpson, E.J.1    Chapman, M.A.S.2    Dawson, J.3
  • 23
    • 0017756117 scopus 로고
    • Simple method for the preparation of single cell suspensions from normal and tumorous rat colonic mucosa
    • Perret V, Lev R, Pigman W. Simple method for the preparation of single cell suspensions from normal and tumorous rat colonic mucosa. Gut. 1977;18:382-385.
    • (1977) Gut , vol.18 , pp. 382-385
    • Perret, V.1    Lev, R.2    Pigman, W.3
  • 24
    • 0021038289 scopus 로고
    • An enzyme-release assay for natural cytotoxicity
    • Korzeniewski C, Callewaert D. An enzyme-release assay for natural cytotoxicity. J Immunol Methods. 1983;64:313-320.
    • (1983) J Immunol Methods , vol.64 , pp. 313-320
    • Korzeniewski, C.1    Callewaert, D.2
  • 25
    • 0027377845 scopus 로고
    • Heal and colonic epithelial metabolism in quiescent ulcerative colitis: Increased glutamine metabolism in distal colon but no defect in butyrate metabolism
    • Finnie IA, Taylor BA, Rhodes JM, et al. Heal and colonic epithelial metabolism in quiescent ulcerative colitis: increased glutamine metabolism in distal colon but no defect in butyrate metabolism. Gut. 1993;34:1552-1558.
    • (1993) Gut , vol.34 , pp. 1552-1558
    • Finnie, I.A.1    Taylor, B.A.2    Rhodes, J.M.3
  • 26
    • 0025881410 scopus 로고
    • Role of mucosal T-cell generated cytokines in epithelial cell injury
    • Targan SR, Deem RL, Shanahan F, et al. Role of mucosal T-cell generated cytokines in epithelial cell injury. Immunol Res. 1991;10:472-478.
    • (1991) Immunol Res , vol.10 , pp. 472-478
    • Targan, S.R.1    Deem, R.L.2    Shanahan, F.3
  • 27
    • 0024453024 scopus 로고
    • Respiratory burst activity of intestinal macrophages in normal and inflammatory bowel disease
    • Mahida YR, Wu K, Jewell DP. Respiratory burst activity of intestinal macrophages in normal and inflammatory bowel disease. Gut. 1989;30:1362-1370.
    • (1989) Gut , vol.30 , pp. 1362-1370
    • Mahida, Y.R.1    Wu, K.2    Jewell, D.P.3
  • 28
    • 0025879878 scopus 로고
    • Changes in phenotypically distinct mucosal macrophage population may be a prerequisite for development of inflammatory bowel disease
    • Allison MC, Poulter LW. Changes in phenotypically distinct mucosal macrophage population may be a prerequisite for development of inflammatory bowel disease. Clin Exp Immunol. 1991;85:504-509.
    • (1991) Clin Exp Immunol , vol.85 , pp. 504-509
    • Allison, M.C.1    Poulter, L.W.2
  • 29
    • 0001010783 scopus 로고    scopus 로고
    • Role of reactive metabolites of oxygen and nitrogen in inflammatory bowel disease: Toxins, mediators, and modulators of gene expression
    • Conner EM, Brand SJ, Davis JM, et al. Role of reactive metabolites of oxygen and nitrogen in inflammatory bowel disease: toxins, mediators, and modulators of gene expression. Inflamm Bowel Dis. 1996;2:133-147.
    • (1996) Inflamm Bowel Dis , vol.2 , pp. 133-147
    • Conner, E.M.1    Brand, S.J.2    Davis, J.M.3
  • 30
    • 0033064252 scopus 로고    scopus 로고
    • The potential role of nitric oxide in chronic inflammatory bowel disorders
    • Perner A, Rask-Madsen J. The potential role of nitric oxide in chronic inflammatory bowel disorders. Aliment Pharmacol Ther. 1999;13:135-144.
    • (1999) Aliment Pharmacol Ther , vol.13 , pp. 135-144
    • Perner, A.1    Rask-Madsen, J.2
  • 31
    • 0031568392 scopus 로고    scopus 로고
    • A major role for matrix metalloproteinases in T cell injury in the gut
    • Pender SL, Tickle SP, Docherty AJP, et al. A major role for matrix metalloproteinases in T cell injury in the gut. J Immunol. 1997;158:1582-1590.
    • (1997) J Immunol , vol.158 , pp. 1582-1590
    • Pender, S.L.1    Tickle, S.P.2    Docherty, A.J.P.3
  • 32
    • 0029670888 scopus 로고    scopus 로고
    • Interleukin 1β down-regulates collagen and augments collagenase expression in human intestinal smooth muscle cells
    • Graham MF, Willey A, Adams J, et al. Interleukin 1β down-regulates collagen and augments collagenase expression in human intestinal smooth muscle cells. Gastroenterology. 1996;110:344-350.
    • (1996) Gastroenterology , vol.110 , pp. 344-350
    • Graham, M.F.1    Willey, A.2    Adams, J.3
  • 33
    • 0024603761 scopus 로고
    • Interleukin-1 and its biologically related cytokines
    • Dinarello CA. Interleukin-1 and its biologically related cytokines. Adv Immunol. 1989;44:153-205.
    • (1989) Adv Immunol , vol.44 , pp. 153-205
    • Dinarello, C.A.1
  • 34
    • 0023803252 scopus 로고
    • IL-6/BSF-2 functions as a killer helper factor in the in vitro induction of cytotoxic T cells
    • Okada M, Kitahara M, Kishimoto S, et al. IL-6/BSF-2 functions as a killer helper factor in the in vitro induction of cytotoxic T cells. J Immunol. 1988;141:1543-1549.
    • (1988) J Immunol , vol.141 , pp. 1543-1549
    • Okada, M.1    Kitahara, M.2    Kishimoto, S.3
  • 35
    • 0024314766 scopus 로고
    • IFN/IL-6 augments the activity of human natural killer cells
    • Luger TA, Krutmann J, Kirnbauer R, et al. IFN/IL-6 augments the activity of human natural killer cells. J Immunol. 1989;143:1206-1209.
    • (1989) J Immunol , vol.143 , pp. 1206-1209
    • Luger, T.A.1    Krutmann, J.2    Kirnbauer, R.3
  • 36
    • 0032694892 scopus 로고    scopus 로고
    • Cytokines in experimental colitis
    • Garside P. Cytokines in experimental colitis. Clin Exp Immunol. 1999;118:337-339.
    • (1999) Clin Exp Immunol , vol.118 , pp. 337-339
    • Garside, P.1
  • 37
    • 0027486125 scopus 로고
    • Location of tumor necrosis factor α by immunohistochemistry in chronic inflammatory bowel disease
    • Murch SH, Braegger CP, Walker-Smith JA, et al. Location of tumor necrosis factor α by immunohistochemistry in chronic inflammatory bowel disease. Gut. 1993;34:1705-1709.
    • (1993) Gut , vol.34 , pp. 1705-1709
    • Murch, S.H.1    Braegger, C.P.2    Walker-Smith, J.A.3
  • 38
    • 0023244682 scopus 로고
    • The effect of recombinant tumor necrosis factor on growth and macromolecular synthesis of human epithelial cells
    • Dealtry GB, Naylor MS, Fiers W, et al. The effect of recombinant tumor necrosis factor on growth and macromolecular synthesis of human epithelial cells. Exp Cell Res. 1987;170:428-438.
    • (1987) Exp Cell Res , vol.170 , pp. 428-438
    • Dealtry, G.B.1    Naylor, M.S.2    Fiers, W.3
  • 39
    • 0023235724 scopus 로고
    • Synergistic antitumor effects of tumor necrosis factor and interferon on human colon carcinoma cell lines
    • Schiller JH, Bittner G, Storer B, et al. Synergistic antitumor effects of tumor necrosis factor and interferon on human colon carcinoma cell lines. Cancer Res. 1987;47:2809-2813.
    • (1987) Cancer Res , vol.47 , pp. 2809-2813
    • Schiller, J.H.1    Bittner, G.2    Storer, B.3
  • 40
    • 0023195347 scopus 로고
    • Toxicity of tumor necrosis factor is synergistic with γ-interferon and can be reduced with cyclooxygenase inhibitors
    • Talmagde JE, Bowersox O, Tribble H, et al. Toxicity of tumor necrosis factor is synergistic with γ-interferon and can be reduced with cyclooxygenase inhibitors. Am J Pathol. 1987;128:410-425.
    • (1987) Am J Pathol , vol.128 , pp. 410-425
    • Talmagde, J.E.1    Bowersox, O.2    Tribble, H.3
  • 41
    • 0025976165 scopus 로고
    • Triggered human mucosal T cells release tumor necrosis factor-alpha and interferon-gamma which kill human colonic epithelial cells
    • Deem RL, Shanahan F, Targan S. Triggered human mucosal T cells release tumor necrosis factor-alpha and interferon-gamma which kill human colonic epithelial cells. Clin Exp Immunol. 1991;83:79-84.
    • (1991) Clin Exp Immunol , vol.83 , pp. 79-84
    • Deem, R.L.1    Shanahan, F.2    Targan, S.3
  • 42
    • 0033451738 scopus 로고    scopus 로고
    • TNF-induced signalling in apoptosis
    • Rath PC, Aggarwal BB. TNF-induced signalling in apoptosis. J Clin Immunol. 1999;19:350-356.
    • (1999) J Clin Immunol , vol.19 , pp. 350-356
    • Rath, P.C.1    Aggarwal, B.B.2
  • 43
    • 0027230947 scopus 로고
    • Effect of cytokines on the epithelial function of the human colon carcinoma cell line HT29 cl 19A
    • Hiribarren A, Heyman M, L'Helgouac'h A, et al. Effect of cytokines on the epithelial function of the human colon carcinoma cell line HT29 cl 19A. Gut. 1993;34:616-620.
    • (1993) Gut , vol.34 , pp. 616-620
    • Hiribarren, A.1    Heyman, M.2    L'Helgouac'h, A.3
  • 44
    • 0033797680 scopus 로고    scopus 로고
    • Cytokine-induced impairment of short-chain fatty acid oxidation and viability in human colonic epithelial cells
    • Pedersen G, Saermark T, Horn T, et al. Cytokine-induced impairment of short-chain fatty acid oxidation and viability in human colonic epithelial cells. Cytokine. 2000;12:1400-1404.
    • (2000) Cytokine , vol.12 , pp. 1400-1404
    • Pedersen, G.1    Saermark, T.2    Horn, T.3
  • 45
    • 0028228827 scopus 로고
    • Mononuclear cells from infants allergic to cow's milk secrete tumor necrosis factor α, altering intestinal function
    • Heyman M, Darmon N, Dupont C, et al. Mononuclear cells from infants allergic to cow's milk secrete tumor necrosis factor α, altering intestinal function. Gastroenterology. 1994;106:1514-1523.
    • (1994) Gastroenterology , vol.106 , pp. 1514-1523
    • Heyman, M.1    Darmon, N.2    Dupont, C.3
  • 46
    • 0028998062 scopus 로고
    • Tumor necrosis factor-α induces morphological and functional alterations of intestinal HT29 cl.19A cell monolayers
    • Rodriguez P, Heyman M, Candalh C, et al. Tumor necrosis factor-α induces morphological and functional alterations of intestinal HT29 cl.19A cell monolayers. Cytokine. 1995;7:441-448.
    • (1995) Cytokine , vol.7 , pp. 441-448
    • Rodriguez, P.1    Heyman, M.2    Candalh, C.3
  • 48
    • 0033061476 scopus 로고    scopus 로고
    • Cytokine regulation of epithelial permeability and ion transport
    • Mc Kay. Cytokine regulation of epithelial permeability and ion transport. Gut. 1999;44:283-289.
    • (1999) Gut , vol.44 , pp. 283-289
    • Mc Kay1
  • 49
    • 0027465109 scopus 로고
    • Tumor necrosis factor depresses gut absorptive function
    • Singh G, Chaudry KI, Morrison MH, et al. Tumor necrosis factor depresses gut absorptive function. Circ Shock. 1993;39:279-284.
    • (1993) Circ Shock , vol.39 , pp. 279-284
    • Singh, G.1    Chaudry, K.I.2    Morrison, M.H.3
  • 50
    • 0027529085 scopus 로고
    • Analysis of enteropathy induced by tumor necrosis factor α
    • Garside P, Bunce C, Tomlinson RC, et al. Analysis of enteropathy induced by tumor necrosis factor α. Cytokine. 1993;5:24-30.
    • (1993) Cytokine , vol.5 , pp. 24-30
    • Garside, P.1    Bunce, C.2    Tomlinson, R.C.3
  • 51
    • 0027409322 scopus 로고
    • Localization of intestinal interleukin 1 activity and protein and gene expression to lamina propria cells
    • Youngman KR, Simon PL, West GA, et al. Localization of intestinal interleukin 1 activity and protein and gene expression to lamina propria cells. Gastroenterology. 1993;104:749-758.
    • (1993) Gastroenterology , vol.104 , pp. 749-758
    • Youngman, K.R.1    Simon, P.L.2    West, G.A.3
  • 52
    • 0027186553 scopus 로고
    • Cytokines in stools of children with inflammatory bowel disease or infective diarrhoea
    • Nicholls S, Stephens S, Braegger S, et al. Cytokines in stools of children with inflammatory bowel disease or infective diarrhoea. J Clin Pathol. 1993;46:757-760.
    • (1993) J Clin Pathol , vol.46 , pp. 757-760
    • Nicholls, S.1    Stephens, S.2    Braegger, S.3
  • 53
    • 0029889689 scopus 로고    scopus 로고
    • Mucosal inflammatory cytokine production by intestinal biopsies in patients with ulcerative colitis and Crohn's disease
    • Reimund JM, Wittersheim C, Dumont S, et al. Mucosal inflammatory cytokine production by intestinal biopsies in patients with ulcerative colitis and Crohn's disease. J Clin Immunol. 1996;16:144-149.
    • (1996) J Clin Immunol , vol.16 , pp. 144-149
    • Reimund, J.M.1    Wittersheim, C.2    Dumont, S.3
  • 54
    • 0034023467 scopus 로고    scopus 로고
    • Measurement of in vivo rectal mucosal cytokine and eicosanoid production in ulcerative colitis using filter paper
    • Carty E, De Brabander M, Feakins RM, et al. Measurement of in vivo rectal mucosal cytokine and eicosanoid production in ulcerative colitis using filter paper. Gut. 2000;46:487-492.
    • (2000) Gut , vol.46 , pp. 487-492
    • Carty, E.1    De Brabander, M.2    Feakins, R.M.3
  • 55
    • 0027457169 scopus 로고
    • New technique to measure mucosal metabolism and its use to map substrate utilization in the healthy human large bowel
    • Chapman MAS, Grahn MF, Giamundo P, et al. New technique to measure mucosal metabolism and its use to map substrate utilization in the healthy human large bowel. Br J Surg. 1993;80:445-449.
    • (1993) Br J Surg , vol.80 , pp. 445-449
    • Chapman, M.A.S.1    Grahn, M.F.2    Giamundo, P.3
  • 56
    • 0034526855 scopus 로고    scopus 로고
    • Cultures of human colonic epithelial cells isolated from endoscopical biopsies from patients with inflammatory bowel disease. Effect of IFNγ, TNFα and IL-1β on viability, butyrate oxidation and IL-8 secretion
    • Pedersen G, Saermark T, Bendtzen K, et al. Cultures of human colonic epithelial cells isolated from endoscopical biopsies from patients with inflammatory bowel disease. Effect of IFNγ, TNFα and IL-1β on viability, butyrate oxidation and IL-8 secretion. Autoimmunity. 2000;32:255-263.
    • (2000) Autoimmunity , vol.32 , pp. 255-263
    • Pedersen, G.1    Saermark, T.2    Bendtzen, K.3
  • 57
    • 0028796715 scopus 로고
    • Selective inhibition of fatty acid oxidation in colonocytes by ibuprofen: A cause of colitis?
    • Roediger WEW, Millard S. Selective inhibition of fatty acid oxidation in colonocytes by ibuprofen: a cause of colitis? Gut. 1995;36:55-59.
    • (1995) Gut , vol.36 , pp. 55-59
    • Roediger, W.E.W.1    Millard, S.2
  • 59
    • 0035167463 scopus 로고    scopus 로고
    • Apoptosis-programmed cell death and its relevance to gastrointestinal epithelium: Survival signal from the matrix
    • Tarnawski AS, Szabo I. Apoptosis-programmed cell death and its relevance to gastrointestinal epithelium: survival signal from the matrix. Gastroenterology. 2001;120:294-298.
    • (2001) Gastroenterology , vol.120 , pp. 294-298
    • Tarnawski, A.S.1    Szabo, I.2
  • 60
    • 0027953456 scopus 로고
    • Butyrate, mesalamine, and factor XIII in experimental colitis in the rat: Effects on transglutaminase activity
    • D'Argenio G, Cosenza V, Sorrentini I, et al. Butyrate, mesalamine, and factor XIII in experimental colitis in the rat: effects on transglutaminase activity. Gastroenterology. 1994;106:399-404.
    • (1994) Gastroenterology , vol.106 , pp. 399-404
    • D'Argenio, G.1    Cosenza, V.2    Sorrentini, I.3
  • 61
    • 0027979012 scopus 로고
    • Butyrate is a potent inhibitor of urokinase secretion by normal colonic epithelium in vitro
    • Gibson PR, Rosella O, Rosella G, et al. Butyrate is a potent inhibitor of urokinase secretion by normal colonic epithelium in vitro. Gastroenterology. 1994;107:410-419.
    • (1994) Gastroenterology , vol.107 , pp. 410-419
    • Gibson, P.R.1    Rosella, O.2    Rosella, G.3
  • 62
    • 85047692516 scopus 로고    scopus 로고
    • Signalling pathways of the TNF superfamily: A double-edged sword
    • Aggarwal B. Signalling pathways of the TNF superfamily: a double-edged sword. Nat Rev Immunol. 2003;3:745-756.
    • (2003) Nat Rev Immunol , vol.3 , pp. 745-756
    • Aggarwal, B.1
  • 64
    • 0032193240 scopus 로고    scopus 로고
    • The regulation and functional consequence of proinflammatory cytokine binding on human intestinal epithelial cells
    • Panja A, Goldberg S, Eckmann L, et al. The regulation and functional consequence of proinflammatory cytokine binding on human intestinal epithelial cells. J Immunol. 1998;161:3675-3684.
    • (1998) J Immunol , vol.161 , pp. 3675-3684
    • Panja, A.1    Goldberg, S.2    Eckmann, L.3
  • 65
    • 0024513152 scopus 로고
    • Cachectin/tumor necrosis factor
    • Tracey KJ, Vlassara H, Cerami A. Cachectin/tumor necrosis factor. Lancet. 1989;i:1122-1126.
    • (1989) Lancet , vol.1 , pp. 1122-1126
    • Tracey, K.J.1    Vlassara, H.2    Cerami, A.3
  • 66
    • 0025201693 scopus 로고
    • Cytotoxic mechanism of tumor necrosis factor-α
    • Larrick JW, Wright SC. Cytotoxic mechanism of tumor necrosis factor-α. FASEB J. 1990;4:3215-3223.
    • (1990) FASEB J , vol.4 , pp. 3215-3223
    • Larrick, J.W.1    Wright, S.C.2
  • 67
    • 0032522666 scopus 로고    scopus 로고
    • A p55 TNF receptor immunoadhesin prevents T cell-mediated intestinal injury by inhibiting matrix metalloproteinase production
    • Pender SLF, Fell JME, Chamow SM, et al. A p55 TNF receptor immunoadhesin prevents T cell-mediated intestinal injury by inhibiting matrix metalloproteinase production. J Immunol. 1998;160:4098-4103.
    • (1998) J Immunol , vol.160 , pp. 4098-4103
    • Pender, S.L.F.1    Fell, J.M.E.2    Chamow, S.M.3
  • 68
    • 0032718351 scopus 로고    scopus 로고
    • Enhancing lamina propria Th1 cell responses with interleukin 12 produces severe tissue injury
    • Monteleone G, MacDonald TT, Wathen NC, et al. Enhancing lamina propria Th1 cell responses with interleukin 12 produces severe tissue injury. Gastroenterology. 1999;117:1069-1077.
    • (1999) Gastroenterology , vol.117 , pp. 1069-1077
    • Monteleone, G.1    MacDonald, T.T.2    Wathen, N.C.3
  • 69
    • 0026713818 scopus 로고
    • Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions
    • Schulze-Osthoff K, Bakker A, Vanhaesebroeck B, et al. Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. J Biol Chem. 1992;267:5317-5323.
    • (1992) J Biol Chem , vol.267 , pp. 5317-5323
    • Schulze-Osthoff, K.1    Bakker, A.2    Vanhaesebroeck, B.3
  • 70
    • 0026487229 scopus 로고
    • Tumor necrosis factor alpha inhibits hepatocyte mitochondrial respiration
    • Stadler J, Bentz BG, Harbrecht BG, et al. Tumor necrosis factor alpha inhibits hepatocyte mitochondrial respiration. Ann Surg. 1992;216:539-546.
    • (1992) Ann Surg , vol.216 , pp. 539-546
    • Stadler, J.1    Bentz, B.G.2    Harbrecht, B.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.