The sustaining effect of three polymers on the release of chlorhexidine from a controlled release drug device for root canal disinfection

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology

Volumn 100, Issue 1, 2005, Pages 105-111

  Lee, Doug Youn ^a   Spångberg, Larz S W ^b   Bok, Young Bin ^a   Lee, Chang Young ^a   Kum, Kee Yeon ^a,c  

^a Yonsei University College of Dentistry   (South Korea)

^b UNIVERSITY OF CONNECTICUT   (United States)

^c Yonsei University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CHITOSAN; CHLORHEXIDINE GLUCONATE; POLY(METHYL METHACRYLATE); POLYGLACTIN; POLYMER; WATER;

ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED DRUG RELEASE; DEVICE; DRUG FORMULATION; POROSITY; SCANNING ELECTRON MICROSCOPY; TOOTH INFECTION; TOOTH ROOT CANAL; ULTRAVIOLET SPECTROPHOTOMETRY;

ANALYSIS OF VARIANCE; ANTI-INFECTIVE AGENTS, LOCAL; CHITOSAN; CHLORHEXIDINE; COATED MATERIALS, BIOCOMPATIBLE; DELAYED-ACTION PREPARATIONS; LACTIC ACID; MATERIALS TESTING; MICROSCOPY, ELECTRON, SCANNING; POLYGLYCOLIC ACID; POLYMERS; POLYMETHYL METHACRYLATE; POROSITY; ROOT CANAL IRRIGANTS; SPECTROPHOTOMETRY, ULTRAVIOLET; SURFACE PROPERTIES;

EID: 20444439481     PISSN: 10792104     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tripleo.2004.08.027     Document Type: Article

References (23)

1. U. Sjögren, D. Figdor, S. Persson, and G. Sundqvist Influence of infection at the time of root filling on the outcome of endodontic treatment of teeth with apical periodontitis Int Endod J 30 1997 297 306
2. G. Sundqvist, D. Figdor, S. Persson, and U. Sjögren Microbiologic analysis of teeth with failed endodontic treatment and the outcome of conservative re-treatment Oral Surg Oral Med Oral Pathol Oral Radiol Endod 85 1998 86 93
3. S. Friedman, R. Komorowski, W. Maillet, R. Klimaite, H.Q. Nguyen, and C.D. Torneck In vivo resistance of coronally induced bacterial ingress by an experimental glass ionomer cement root canal sealer J Endod 26 2000 1 5
4. A. Byström, R. Claesson, and G. Sundqvist The antimicrobial effect of camphorated paramonochlorophenol, camphorated phenol and calcium hydroxide in the treatment of infected root canals Endod Dent Traumatol 1 1985 170 175
5. M. Cvek, L. Hollender, and C.E. Nord Treatment of non-vital permanent incisors with calcium hydroxide Odontol Revy 27 1976 93 108
6. D. Ørstavik, and M. Haapasalo Disinfection by endodontic irrigants and dressings by experimentally infected dentinal tubules Endod Dent Traumatol 6 1990 142 149
7. D. Ørstavik, and M. Haapasalo In-vitro infection and disinfection of dentinal tubules J Dent Res 66 1987 1375 1379
8. B.P.F.A. Gomes, S.F.C. Souza, C.C.R. Ferraz, F.B. Teizeira, A.A. Zaia, and L. Valdrigh Effectiveness of 2% chlorhexidine gel and calcium hydroxide against Enterococcus faecalis in bovine root dentine in vitro Int Endod J 36 2003 267 275
9. B. Basrani, L. Tjaderhane, M. Santos, E. Pascon, H. Grad, and H.P. Lawrence Efficacy of chlorhexidine- and hydroxide-containing medicaments against Enterococcus faecalis in vitro Oral Surg Oral Med Oral Pathol Oral Radiol Endod 96 2003 618 624
10. M.E. Vianna, B.P. Gomes, V.B. Berber, A.A. Zaia, C.C. Ferraz, and F.J. de Souza-Filho In vitro evaluation of the antimicrobial activity of chlorhexidine and sodium hypochlorite Oral Surg Oral Med Oral Pathol Oral Radiol Endod 97 2004 79 84
11. M.J. Jeansonne, and R.R. White A comparison of 2% chlorhexidine gluconate and 5.25% sodium hypochlorite as antimicrobial endodontic irrigants J Endod 20 1994 276 278
12. R.R. White, G.L. Hay, and L.R. Janer Residual antimicrobial activity after canal irrigation with chlorhexidine J Endod 23 1997 229 231
13. B. Barsani, J.M. Santos, L. Tjaderhane, H. Grad, O. Gorduysus, and J. Huang Substantive antimicrobial activity in chlorhexidine-treated human root dentin Oral Surg Oral Med Oral Pathol Oral Radiol Endod 94 2002 240 245
14. R. Komorowski, H. Grad, Y. Wu, and S. Friedman Antimicrobial substantivity of chlorhexedine-treated bovine root dentin J Endod 26 2000 315 317
15. S. Jung, K. Safavi, and L. Spångberg The effectiveness of Chlorhexidine in the prevention of root canal reinfection [abstract] J Endod 25 1999 288
16. I. Heling, M. Sommer, D. Steinberg, M. Friedman, and M.N. Sela Microbiological evaluation of the efficacy of chlorhexidine in a sustained-release device for dentine sterilization Int Endod J 25 1992 15 19
17. 2 in preventing secondary infection of dentinal tubules Int Endod J 25 1992 20 24
18. S. Miyazaki, H. Yamaguchi, C. Yokouchi, M. Takada, and W.M. Hou Sustained-release and intragastric-floating granules of indomethacin using chitosan in rabbits Chem Pharm Bull 36 1988 4033 4038
19. M.A. James, and S.S. Matthew Biodegradation and biocompatibility of PLA and PLGA microsphers Adv Drug Rev 28 1997 5 24
20. D. Cam, S.H. Hyon, and Y. Ikada Degradation of high molecular weight poly (L-lactide) in alkaline medium Biomaterials 16 1998 833 843
21. R. Bayston, and R.D.G. Milner The sustained release of antimicrobial drugs from bone cement J Bone Joint Surg 64B 1982 460 464
22. J. Huang, H.L. Wong, Y. Zhou, X.Y. Wu, H. Grad, and R. Komorowski In vitro studies and modeling of a controlled-release device for root canal therapy J Cont Rel 67 2000 293 307
23. A.K. Singla, and M. Chawla Chitosan: some pharmaceutical and biological aspects - an update J Pharm Pharmcol 53 2001 1047 1067