Characteristics of childhood and adult-onset type 1 diabetes in a multi-ethnic population

Diabetes Research and Clinical Practice

Volumn 69, Issue 1, 2005, Pages 22-28

  Rodacki, Melanie ^a,b,c   Zajdenverg, Lenita ^a   Tortora, Rosangela Prendin ^a   Reis, Fabiola Aarao ^a   Albernaz, Martha S ^a   Bencke Goncalves, Maria Rocio ^a   Milech, Adolpho ^a   Paulo De Oliveira, Jose Egidio ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b JOSLIN DIABETES CENTER   (United States)

^c Instituto Estadual de Diabetes e Endocrinologia Luiz Capriglione   (Brazil)

Author keywords

Adult; GADA; HLA DR antigens; Type 1 diabetes

Indexed keywords

GLUTAMATE DECARBOXYLASE ANTIBODY; HLA DR ANTIGEN;

ADULT; AGE DISTRIBUTION; ARTICLE; BLOOD SAMPLING; BRAZIL; CHILDHOOD DISEASE; CLINICAL FEATURE; DIABETIC KETOACIDOSIS; DISEASE DURATION; ETHNOLOGY; FEMALE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; MATURITY ONSET DIABETES MELLITUS; ONSET AGE; POPULATION RESEARCH; PREVALENCE; STATISTICAL SIGNIFICANCE; SYMPTOMATOLOGY;

ADULT; CHILD; DIABETES MELLITUS, TYPE 1; ETHNIC GROUPS; FAMILY; FEMALE; HLA-DR ANTIGENS; HUMANS; INSULIN ANTIBODIES; MALE;

EID: 20444432410     PISSN: 01688227     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diabres.2004.11.006     Document Type: Article

References (36)

1. M.A. Kelly, M.L. Rayner, and C.H. Mijovic Molecular aspects of type 1 diabetes Mol. Pathol. 56 1 2003 1 10
2. M. Laakso, and K. Pyorala Age of onset and type of diabetes Diab. Care 8 1985 114 117
3. A.G. Molbak, B. Christau, and B. Marner Incidence of insulin-dependent diabetes mellitus in age groups over 30 years in Denmark Diab. Med. 11 1994 650 655
4. M.I. Hawa, H. Beyan, Buckley, and R.D.G. Leslie Impact of genetic and non-genetic factors in type 1 diabetes Am. J. Med. Genet. 115 2002 8 17
5. V. Hyttinen, J. Kaprio, L. Kinnunen, M. Koskenvuo, and J. Tuomilehto Genetic liability of type 1 diabetes and the onset age among 22.650 young Finnish twin pairs Diabetes 52 2003 1052 1055
6. P. Pozzilli, and U. Di Mario Autoimmune diabetes not requiring insulin at diagnosis (latent autoimmune diabetes of the adult) Diab. Care 24 2001 1460 1467
7. E. Sabbah, K. Savola, T. Ebeling, P. Kulmala, P. Vahasalo, and J. Ilonen Genetic, autoimmune and clinical characteristics of childhood and adult onset type 1 diabetes Diab. Care 23 9 2000 1326 1332
8. T. Lohmann, J. Sessler, H.J. Verlohren, S. Schroder, J. Rotger, and K. Dahn Distinct genetic and immunological features in patients with insulin-dependent diabetes below and above age 40 at onset Diab. Care 20 1997 524 529
9. J. Karjalainen, P. Salmela, J. Ilonen, H.M. Surcel, and M. Knip A comparison of childhood and adult type I diabetes mellitus N. Engl. J. Med. 320 1989 881 886
10. A.P. Lambert, K.M. Gillespie, G. Thomson, H.J. Cordell, J.A. Todd, and E.A. Gale Absolute risk of childhood-onset type 1 diabetes defined by human leucocyte antigen class II genotype: a population-based study in the United Kingdom J. Clin. Endocr. Metab. 89 8 2004 4037 4043
11. M. Cerna, P. Novota, and K. Kolostova HLA in Czech adult patients with autoimmune diabetes mellitus: comparison with Czech children with type 1 diabetes and patients with type 2 diabetes Eur. J. Immunogenet. 30 2003 401 407
12. B. Berger, G. Stenstrom, and G. Sundkvist Random C-peptide in the classification of diabetes Scand. J. Clin. Lab. Invest. 60 8 2000 687 693
13. P. Cravarezza, E. Radaeli, C. Toffoli, and C. Rigosa Discrimination of type I from insulin treated type II diabetic patients by C-peptide measurement Acta Diabetologica Latina 23 1986 345 350
14. A. Ramachandran, C. Snehalatha, K. Satyavani, S. Sivasankari, and V. Vijay Type 2 diabetes in Asian-Indian urban children Diab. Care 26 2003 1022 1025
15. P.J. Bingley, E. Bonifacio, and P.W. Mueller Diabetes Antibody Standardization Program: First Assay Proficiency Evaluation Diabetes 52 2003 1128 1136
16. P.A. Zalloua, H. Shbaklo, G. Halaby, H. Terwedow, X. Xu, and S.T. Azar Type 2 diabetes family history delays the onset of type 1 diabetes J. Clin. Endocrinol. Metab. 87 7 2002 3192 3196
17. N. Hosszufalusi, A. Vatay, K. Rajczy, Z. Prohaszka, E. Pozsonyi, and L. Horvath Similar genetic features and different islet cell autoantibody pattern of latent autoimmune diabetes in adults (LADA) compared with adult-onset type 1 diabetes with rapid progression Diab. Care 26 2 2003 452 457
18. U. Masharani, and J. Karam Pancreatic hormones and diabetes mellitus F.S. Greenspan D.G. Gardner Basic and Clinical Endocrinology sixth ed. 2001 Mc Graw-Hill San Francisco pp. 623-698
19. C. Mijovic, D. Jenkins, K. Jacobs, M.A. Penny, J.A. Fletcher, and A.H. Barnett HLA DQA1 and DQB1 alleles are associated with genetic susceptibility to type 1 diabetes in a Black population Diabetes 40 1991 748 753
20. D.E. Undlien, T. Friede, H.G. Rammensee, G. Joner, K. Dahl-Jorgensen, and O. Sovik HLA-encoded genetic predisposition in IDDM. DR 4 subtypes may be associated with different degrees of protection Diabetes 46 1997 143 149
21. S. Caillat-Zucman, H.J. Garchon, J. Timsit, R. Assan, C. Boitard, and I. Djilali-Saiah Age dependent HLA genetic heterogeneity of type I insulin dependent diabetes mellitus J. Clin. Invest. 90 1992 2242 2250
22. S.H. Chan, A.C. Thai, Y.N. Lin, K.F. Liu, and G.B. Wee Influence of gender and age at onset on the HLA associations in Chinese with insulin-dependent diabetes mellitus Hum. Immunol. 44 3 1995 175 180
23. A.M. Valdes, G. Thompson, H.A. Erlich, and J.A. Noble Association between type 1 diabetes age of onset and HLA among sibling pairs Diabetes 48 1999 1658 1661
24. B.D. Tait, L.C. Harrison, B.P. Drummond, V. Stewart, M.D. Varney, and M.C. Honeyman HLA antigens and age at diagnosis of insulin-dependent diabetes mellitus Hum. Immunol. 42 2 1995 116 122
25. T. Fujisawa, H. Ikegami, Y. Kawaguchi, E. Yamato, K. Takekawa, and Y. Nakagawa Class I HLA is associated with age-at-onset of IDDM, while class II HLA confers susceptibility to IDDM Diabetologia 38 12 1995 1493 1495
26. Y. Kawabata, H. Ikegami, Y. Kawaguchi, T. Fujisawa, M. Hotta, and H. Ueda Age-related association of MHC class I chain-related gene A (MICA) with type 1 (insulin dependent) diabetes mellitus Hum. Immunol. 61 6 2000 624 629
27. H. Obayashi, N. Nakamura, M. Fukui, H. Tegoshi, M. Fujii, and M. Ogata Influence of TNF microsatellite polymorphisms (TNFa) on age at onset of insulin dependent diabetes mellitus Hum. Immunol. 60 1999 974 978
28. B.D. Tait, P.G. Colman, L. Marchinovska, L. Marchinovska, E. Dore, and S. Gellert HLA genes associated with autoimmunity and progression to disease in type 1 diabetes Tissue Antigens 61 2003 146 153
29. S. Genovese, R. Bonfanti, E. Bazzigaluppi, V. Lampasona, E. Benazzi, and E. Bosi Association of IA-2 autoantibodies with HLA DR4 phenotypes in IDDM Diabetologia 39 10 1996 1223 1226
30. M. Knip, M. Kukko, P. Kulmala, R. Veijola, O. Simell, and H.K. Akerblom Humoral beta-cell autoimmunity in relation to HLA-defined disease susceptibility in preclinical and clinical type 1 diabetes Am. J. Med. Genet. 115 2002 48 54
31. R. Hermann, Z. Gombos, E. Gyurus, G. Soltesz, Prevalence and predictive value of GAD 65 antibodies and their correlation with HLA DR-DQ in children with type 1 diabetes, Orv. Hetil. 23 144 (8) (2003) 355-360.
32. S.W. Serjeantson, Kohonen-Corish MRJ, M.J. Rowley, I.R. Mackay, W. Knowles, and P. Zimmet Antibodies to glutamic acid decarboxylase are associated with HLA-DR genotypes in both Australian and Asians with type 1 (insulin-dependent) diabetes mellitus Diabetologia 35 1992 996 1001
33. T. Battelino, N. Ursic-Bratina, V. Dolzan, M. Stopar-Obreza, P. Pozzilli, and C. Krzisnik The HLA DR B-DQ polymorphism and anti-insulin antibody response in Slovenian patients with type 1 diabetes Eur. J. Immunogenet. 30 2003 223 227
34. M. Serrano-Rios, M.D. Gutierrez-Lopez, F. Perez-Bravo, M.T. Martinez, J. Antona, and M. Rowley HLA-DR, DQ and anti-GAD antibodies in first degree relatives of type I diabetes mellitus Diab. Res. Clin. Pract. 34 Suppl 1996 S133 S139
35. H. Takeda, E. Kawasaki, I. Shimizu, E. Konoue, M. Fujiyama, and S. Murao Ethime Study. Clinical, autoimmune and genetic characteristics of adult-onset diabetic patients with GAD autoantibodies in Japan (Ethime Study) Diab. Care 25 6 2002 995 1001
36. R.S. Abraham, Y.C. Kudva, S.B. Wilson, J.L. Strominger, and C.S. David Co-expression of HLA DR3 and DQ8 results in the development of spontaneous insulitis and loss of tolerance to GAD 65 in transgenic mice Diabetes 49 4 2000 548 554