Inhibition of the mitochondrial ATP synthesis by polygodial, a naturally occurring dialdehyde unsaturated sesquiterpene

Biochemical Pharmacology

Volumn 70, Issue 1, 2005, Pages 82-89

  Castelli, María V ^a   Lodeyro, Anabella F ^a   Malheiros, Angela ^b   Zacchino, Susana A S ^a   Roveri, Oscar A ^a  

^a UNIVERSIDAD NACIONAL DE ROSARIO   (Argentina)

^b UNIVERSIDADE DO VALE DO ITAJAÍ   (Brazil)

Author keywords

Antifungal; ATP synthesis; Mechanism; Mitochondria; Polygodial; Uncoupler

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; POLYGODIAL; SUCCINATE DEHYDROGENASE;

ANIMAL TISSUE; ANTIFUNGAL ACTIVITY; ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; COW; DRUG MECHANISM; ELECTRON TRANSPORT; ENERGY METABOLISM; ENZYME ACTIVITY; HEART MITOCHONDRION; IC 50; LIVER MITOCHONDRION; MITOCHONDRIAL RESPIRATION; NONHUMAN; PRIORITY JOURNAL; RAT;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIFUNGAL AGENTS; CARBONYL CYANIDE P-TRIFLUOROMETHOXYPHENYLHYDRAZONE; ENERGY METABOLISM; MEMBRANE POTENTIALS; MITOCHONDRIA; RATS; SESQUITERPENES; UNCOUPLING AGENTS;

EID: 20444429437     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2005.04.016     Document Type: Article

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