Use of carcinoembryonic antigen gene promoter in colorectal carcinoma-specific suicidal gene therapy

Acta Biochimica et Biophysica Sinica

Volumn 30, Issue 1, 1998, Pages 6-8

  Jiang, Qiong ^a   Ge, Kai ^a   Xu, De Hua ^a   Sun, Lan Ying ^a   Zheng, Zhong Cheng ^a   Liu, Xin Yuan ^a  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

Apoptosis; CD gene; CEA promoter; Gene therapy; Human colorectal carcinoma

Indexed keywords

EID: 20444424981     PISSN: 05829879     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Tang Z Y ed. Modern Oncology, Shanghai: Shanghai Medical University Publishing House, 1993, 521-552
2. Jiang Q, Ge K, Xu D H et al. Expression of cytosine deaminase gene in human colon carcinoma cells by recombinant retroviral vector. Acta Biochimica et Biophysica Sinica, 1997, 29(2): 135-141
3. Schrewe H, Thompson J, Bona M et al. Cloning of the complete gene for carcinoembryonic antigen; Analysis of its promoter indicates a region conveying cell type-specific expression. Mol Cell Biol, 1990, 10(6): 2738-2748
4. Sambrook J, Fritsch E F, Maniatis T. Molecular Cloning: A Laboratory Manual, 2nd ed, New York: Cold Spring Harbor Laboratory Press, 1989
5. Li C S, Huang L X, Zhang S Y et al. In, The Society of Chinese Sciences and Technologies ed. Tumor Prevention and Treatment, Beijing: Chinese Scientific and Technical Publishing House. 1989, 282
6. Lobo-Alfonso J, Samrock R, Price P. Isolation and culture of hepatocytes. Focus, 1995, 17(1): 6-9
7. Huber B E, Austin E A, Richards C A et al. Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: Significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase. Proc Natl Acad Sci USA, 1994, 91: 8302-8306
8. Shchepotin I B, Soldatenkov V, Buras R R et al. Apoptosis of human primary and metastatic colon adenocarcinoma cell lines in vitro induced by 5-fluorouracil, verapamil, and hyperthermia. Anticancer Res, 1994, 14: 1027-1031
9. Wu Y, Yuan S C ed. The Pharmacopoeia of People's Republic of China (2nd Part) : The Notices for Using Drugs Clinically, Beijingi Chinese Medical Scientific and Technical Publishing House. 1989, 419, 459