Age related optic nerve axonal loss in adult Brown Norway rats

Experimental Eye Research

Volumn 80, Issue 6, 2005, Pages 877-884

  Cepurna, William O ^a   Kayton, Robert J ^a   Johnson, Elaine C ^a   Morrison, John C ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Aging; Axonal transport; Axons; Glaucoma; Neurodegenerative diseases; Optic nerve

Indexed keywords

AGING; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; GLAUCOMA; NERVE DEGENERATION; NERVE FIBER TRANSPORT; NONHUMAN; OPTIC NERVE; PATHOPHYSIOLOGY; PRIMATE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; RAT STRAIN; RETINA; STATISTICAL MODEL; STATISTICAL SIGNIFICANCE; TRANSMISSION ELECTRON MICROSCOPY;

AGING; ANIMALS; AXONS; CELL COUNT; INTRAOCULAR PRESSURE; MICROSCOPY, ELECTRON; NERVE DEGENERATION; NEUROGLIA; OPTIC NERVE; RATS; RATS, INBRED BN;

EID: 20444419808     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2004.12.021     Document Type: Article

References (61)

1. F. Ahmed, K.M. Brown, D.A. Stephan, J.C. Morrison, E.C. Johnson, and S.I. Tomarev Microarray analysis of changes in mRNA levels in the rat retina after experimental elevation of intraocular pressure Invest. Ophthalmol. Vis. Sci. 45 2004 1247 1258
2. M. Aihara, J.D. Lindsey, and R.N. Weinreb Experimental mouse ocular hypertension: establishment of the model Invest. Ophthalmol. Vis. Sci. 44 2003 4314 4320
3. K.S. Bedi, and M.A. Warren The effects of undernutrition during early life on the rat optic nerve fibre number and size-frequency distribution J. Comp. Neurol. 219 1983 125 132
4. E. Bergman, and B. Ulfhake Loss of primary sensory neurons in the very old rat: neuron number estimates using the disector method and confocal optical sectioning J. Comp. Neurol. 396 1998 211 222
5. S. Bruesch, and L. Arey The number of myelinated and unmyelinated fibers in the optic nerve ov vertebrates J. Comp. Neurol. 77 1944 631 640
6. B.C. Chauhan, J. Pan, M.L. Archibald, T.L. LeVatte, M.E. Kelly, and F. Tremblay Effect of intraocular pressure on optic disc topography, electroretinography, and axonal loss in a chronic pressure-induced rat model of optic nerve damage Invest. Ophthalmol. Vis. Sci. 43 2002 2969 2976
7. J. Danias, K.C. Lee, M.F. Zamora, B. Chen, F. Shen, T. Filippopoulos, Y. Su, D. Goldblum, S.M. Podos, and T. Mittag Quantitative analysis of retinal ganglion cell (RGC) loss in aging DBA/2NNia glaucomatous mice: comparison with RGC loss in aging C57/BL6 mice Invest. Ophthalmol. Vis. Sci. 44 2003 5151 5162
8. J. De Juan, C. Iniguez, and J. Carreres Number, diameter and distribution of the rat optic nerve fibers Acta Anat. 102 1978 294 299
9. I. Dielemans, J.R. Vingerling, R.C. Wolfs, A. Hofman, D.E. Grobbee, and P.T. de Jong The prevalence of primary open-angle glaucoma in a population-based study in The Netherlands. The Rotterdam Study Ophthalmology 101 1994 1851 1855
10. J. Forrester, and A. Peters Nerve fibres in optic nerve of rat Nature 214 1967 245 247
11. B. Fortune, B.V. Bui, J.C. Morrison, E.C. Johnson, J. Dong, W.O. Cepurna, L. Jia, S. Barber, and G.A. Cioffi Selective ganglion cell functional loss in rats with experimental glaucoma Invest. Ophthalmol. Vis. Sci. 45 2004 1854 1862
12. Y. Fukuda, T. Sugimoto, and T. Shirokawa Strain differences in quantitative analysis of the rat optic nerve Exp. Neurol. 75 1982 525 532
13. D. Gaasterland, and C. Kupfer Experimental glaucoma in the rhesus monkey Invest. Ophthalmol. 13 1974 455 457
14. M.O. Gordon, J.A. Beiser, J.D. Brandt, D.K. Heuer, E.J. Higginbotham, C.A. Johnson, J.L. Keltner, J.P. Miller, R.K. Parrish 2nd, M.R. Wilson, and M.A. Kass The Ocular Hypertension Treatment Study: baseline factors that predict the onset of primary open-angle glaucoma Arch. Ophthalmol. 120 2002 714 720 (discussion 829-730)
15. S. Grozdanic, D.S. Sakaguchi, Y.H. Kwon, R.H. Kardon, and I.M. Sonea Characterization of the pupil light reflex, electroretinogram and tonometric parameters in healthy rat eyes Curr. Eye Res. 25 2002 69 78
16. S.D. Grozdanic, D.M. Betts, D.S. Sakaguchi, Y.H. Kwon, R.H. Kardon, and I.M. Sonea Temporary elevation of the intraocular pressure by cauterization of vortex and episcleral veins in rats causes functional deficits in the retina and optic nerve Exp. Eye Res. 77 2003 27 33
17. S.D. Grozdanic, D.S. Sakaguchi, Y.H. Kwon, R.H. Kardon, and I.M. Sonea Functional characterization of retina and optic nerve after acute ocular ischemia in rats Invest. Ophthalmol. Vis. Sci. 44 2003 2597 2605
18. V.A. Hanninen, M.B. Pantcheva, E.E. Freeman, N.R. Poulin, and C.L. Grosskreutz Activation of caspase 9 in a rat model of experimental glaucoma Curr. Eye Res. 25 2002 389 395
19. A. Hughes The pigmented-rat optic nerve: fibre count and fibre diameter spectrum J. Comp. Neurol. 176 1977 263 268
20. A. Hunter, and K.S. Bedi A quantitative morphological study of interstrain variation in the developing rat optic nerve J. Comp. Neurol. 245 1986 160 166
21. C.J. Jeon, E. Strettoi, and R.H. Masland The major cell populations of the mouse retina J. Neurosci. 18 1998 8936 8946
22. L. Jia, W.O. Cepurna, E.C. Johnson, and J.C. Morrison Patterns of intraocular pressure elevation after aqueous humor outflow obstruction in rats Invest. Ophthalmol. Vis. Sci. 41 2000 1380 1385
23. J.B. Jonas, J.A. Muller-Bergh, U.M. Schlotzer-Schrehardt, and G.O. Naumann Histomorphometry of the human optic nerve Invest. Ophthalmol. Vis. Sci. 31 1990 736 744
24. J.B. Jonas, A.M. Schmidt, J.A. Muller-Bergh, U.M. Schlotzer-Schrehardt, and G.O. Naumann Human optic nerve fiber count and optic disc size Invest. Ophthalmol. Vis. Sci. 33 1992 2012 2018
25. B.E. Klein, R. Klein, W.E. Sponsel, T. Franke, L.B. Cantor, J. Martone, and M.J. Menage Prevalence of glaucoma. The Beaver Dam Eye Study Ophthalmology 99 1992 1499 1504
26. Kuchel, G.A., Poon, T., Irshad, K., Richard, C., Julien, J.P., Cowen, T. (1996). Decreased neurofilament gene expression is an index of selective axonal hypotrophy in ageing. Neuroreport 7, 1353-1359.
27. H. Levkovitch-Verbin, H.A. Quigley, K.R. Martin, D. Valenta, L.A. Baumrind, and M.E. Pease Translimbal laser photocoagulation to the trabecular meshwork as a model of glaucoma in rats Invest. Ophthalmol. Vis. Sci. 43 2002 402 410
28. J.V. Lovasik, M.J. Kergoat, L. Justino, and H. Kergoat Neuroretinal basis of visual impairment in the very elderly Graefes Arch. Clin. Exp. Ophthalmol. 241 2003 48 55
29. F. Mabuchi, M. Aihara, M.R. Mackey, J.D. Lindsey, and R.N. Weinreb Optic nerve damage in experimental mouse ocular hypertension Invest. Ophthalmol. Vis. Sci. 44 2003 4321 4330
30. T.M. Mayhew How to count synapses unbiasedly and efficiently at the ultrastructural level: proposal for a standard sampling and counting protocol J. Neurocytol. 25 1996 793 804
31. S.J. McKinnon, D.M. Lehman, N.G. Tahzib, N.L. Ransom, H.A. Reitsamer, P. Liston, E. LaCasse, Q. Li, R.G. Korneluk, and W.W. Hauswirth Baculoviral IAP Repeat-containing-4 Protects Optic Nerve Axons in a Rat Glaucoma Model Mol. Ther. 5 2002 780 787
32. I.G. McQuarrie, S.T. Brady, and R.J. Lasek Retardation in the slow axonal transport of cytoskeletal elements during maturation and aging Neurobiol. Aging 10 1989 359 365
33. F.S. Mikelberg, S.M. Drance, M. Schulzer, H.M. Yidegiligne, and M.M. Weis The normal human optic nerve. Axon count and axon diameter distribution Ophthalmology 96 1989 1325 1328
34. P. Mitchell, W. Smith, K. Attebo, and P.R. Healey Prevalence of open-angle glaucoma in Australia. The Blue Mountains Eye Study Ophthalmology 103 1996 1661 1669
35. C.G. Moore, S.T. Milne, and J.C. Morrison Noninvasive measurement of rat intraocular pressure with the Tono-Pen Invest. Ophthalmol. Vis. Sci. 34 1993 363 369
36. C.G. Moore, D. Epley, S.T. Milne, and J.C. Morrison Long-term non-invasive measurement of intraocular pressure in the rat eye Curr. Eye Res. 14 1995 711 717
37. C.G. Moore, E.C. Johnson, and J.C. Morrison Circadian rhythm of intraocular pressure in the rat Curr. Eye Res. 15 1996 185 191
38. J.C. Morrison, L.C. Cork, G.R. Dunkelberger, A. Brown, and H.A. Quigley Aging changes of the rhesus monkey optic nerve Invest. Ophthalmol. Vis. Sci. 31 1990 1623 1627
39. J.C. Morrison, C.G. Moore, L.M. Deppmeier, B.G. Gold, C.K. Meshul, and E.C. Johnson A rat model of chronic pressure-induced optic nerve damage Exp. Eye Res. 64 1997 85 96
40. J.C. Morrison, W.O. Cepurna, and E.C. Johnson Modeling glaucomatous optic nerve damage Int. Ophthalmol. Clin. 39 1999 29 41
41. Morrison, J.C., Johnson, E.C., Cepurna, W.O., Jia, L., 2005. Understanding mechanisms of pressure-induced optic nerve damage. Progr. Retinal Eye Res. 24, 217-240.
42. A.H. Neufeld, and E.N. Gachie The inherent, age-dependent loss of retinal ganglion cells is related to the lifespan of the species Neurobiol. Aging 24 2003 167 172
43. S. Panda-Jonas, J.B. Jonas, and M. Jakobczyk-Zmija Retinal photoreceptor density decreases with age Ophthalmology 102 1995 1853 1859
44. I.M. Parhad, J.N. Scott, L.A. Cellars, J.S. Bains, C.A. Krekoski, and A.W. Clark Axonal atrophy in aging is associated with a decline in neurofilament gene expression J. Neurosci. Res. 41 1995 355 366
45. V.H. Perry, Z. Henderson, and R. Linden Postnatal changes in retinal ganglion cell and optic axon populations in the pigmented rat J. Comp. Neurol. 219 1983 356 368
46. A. Peters The effects of normal aging on myelin and nerve fibers: a review J. Neurocytol. 31 2002 581 593
47. M.X. Repka, and H.A. Quigley The effect of age on normal human optic nerve fiber number and diameter Ophthalmology 96 1989 26 32
48. A. Ricci, E. Bronzetti, and F. Amenta Effect of ageing on the nerve fibre population of rat optic nerve Gerontology 34 1988 231 235
49. J.H. Sandell, and A. Peters Effects of age on nerve fibers in the rhesus monkey optic nerve J. Comp. Neurol. 429 2001 541 553
50. A. Sawada, and A.H. Neufeld Confirmation of the rat model of chronic, moderately elevated intraocular pressure Exp. Eye Res. 69 1999 525 531
51. C.L. Schlamp, E.C. Johnson, Y. Li, J.C. Morrison, and R.W. Nickells Changes in Thy1 gene expression associated with damaged retinal ganglion cells Mol. Vis. 7 2001 192 201
52. S.R. Shareef, E. Garcia-Valenzuela, A. Salierno, J. Walsh, and S.C. Sharma Chronic ocular hypertension following episcleral venous occlusion in rats [letter] Exp. Eye Res. 61 1995 379 382
53. T. Sugimoto, Y. Fukuda, and K. Wakakuwa Quantitative analysis of a cross-sectional area of the optic nerve: a comparison between albino and pigmented rats Exp. Brain Res. 54 1984 266 274
54. W.G. Tatton, C.E. Greenwood, M.C. Verrier, D.P. Holland, M.M. Kwan, and F.E. Biddle Different rates of age-related loss for four murine monoaminergic neuronal populations Neurobiol. Aging 12 1991 543 556
55. J.M. Tielsch, A. Sommer, J. Katz, R.M. Royall, H.A. Quigley, and J. Javitt Racial variations in the prevalence of primary open-angle glaucoma. The Baltimore Eye Survey [see comments] JAMA 266 1991 369 374
56. M.J. Tjon-Fo-Sang, J. de Vries, and H.G. Lemij Measurement by nerve fiber analyzer of retinal nerve fiber layer thickness in normal subjects and patients with ocular hypertension Am. J. Ophthalmol. 122 1996 220 227
57. W.M. Treff, E. Meyer-Konig, and W. Schlote Morphometric analysis of a fibre system in the central nervous system J. Microsc. 95 1972 337 343
58. R.N. Weinreb, S. Shakiba, P.A. Sample, S. Shahrokni, S. van Horn, V.S. Garden, S. Asawaphureekorn, and L. Zangwill Association between quantitative nerve fiber layer measurement and visual field loss in glaucoma Am. J. Ophthalmol. 120 1995 732 738
59. M.D. Wensor, C.A. McCarty, Y.L. Stanislavsky, P.M. Livingston, and H.R. Taylor The prevalence of glaucoma in the Melbourne Visual Impairment Project Ophthalmology 105 1998 733 739
60. M. Zulauf Normal visual fields measured with Octopus Program G1. I. Differential light sensitivity at individual test locations Graefes Arch. Clin. Exp. Ophthalmol. 232 1994 509 515
61. M. Zulauf, R.P. LeBlanc, and J. Flammer Normal visual fields measured with Octopus-Program G1. II. Global visual field indices Graefes Arch. Clin. Exp. Ophthalmol. 232 1994 516 522