Cord blood immunology and stem cell transplantation

Human Immunology

Volumn 66, Issue 5, 2005, Pages 431-446

  Bradley, M Brigid ^a   Cairo, Mitchell S ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Cord blood; Cord blood baking; Cord blood transplantation; Ex vivo; Immunology

Indexed keywords

ALEMTUZUMAB; BUSULFAN; CD45 ANTIGEN; CD45RO ANTIGEN; COLONY STIMULATING FACTOR 1; CYCLOPHOSPHAMIDE; CYTOKINE; FLUDARABINE; GAMMA INTERFERON; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HLA ANTIGEN; INTERLEUKIN 11; INTERLEUKIN 12; INTERLEUKIN 15; INTERLEUKIN 18; INTERLEUKIN 4; INTERLEUKIN 8; MELPHALAN; THYMOCYTE ANTIBODY; TUMOR NECROSIS FACTOR ALPHA;

ACUTE GRAFT VERSUS HOST DISEASE; ACUTE GRANULOCYTIC LEUKEMIA; ALLOGENEIC STEM CELL TRANSPLANTATION; ANEMIA; APLASTIC ANEMIA; ARTICLE; BACTERIAL INFECTION; BETA THALASSEMIA; BLOOD BANK; BLOOD SAMPLING; BONE MARROW DEPRESSION; BONE MARROW TRANSPLANTATION; CELL POPULATION; CELL PROLIFERATION; CELLULAR IMMUNITY; CHIMERA; CRYOPRESERVATION; FANCONI ANEMIA; HEMATOPOIETIC STEM CELL; HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; HLA SYSTEM; HODGKIN DISEASE; HUMAN; IMMUNE DEFICIENCY; IMMUNOLOGY; INFECTION COMPLICATION; LEUKEMIA; METABOLIC DISORDER; MYCOSIS; MYELOABLATIVE CONDITIONING; MYELODYSPLASTIC SYNDROME; NEUROBLASTOMA; NONHODGKIN LYMPHOMA; PRIORITY JOURNAL; RECURRENT DISEASE; REDUCED INTENSITY CONDITIONING; STORAGE DISEASE; SURVIVAL; T LYMPHOCYTE; THAWING; UMBILICAL CORD BLOOD; WISKOTT ALDRICH SYNDROME;

BLOOD BANKS; BONE MARROW TRANSPLANTATION; CORD BLOOD STEM CELL TRANSPLANTATION; FETAL BLOOD; GRAFT VS HOST DISEASE; HLA ANTIGENS; HUMANS; TRANSPLANTATION CONDITIONING; TRANSPLANTATION, HOMOLOGOUS;

EID: 20444398532     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2005.01.010     Document Type: Article

References (101)

1. R.D. Christensen Hematopoiesis in the fetus and neonate Pediatr Res 26 1989 531
2. J. Kovarik, C.A. Siegrist Immunity in early life Immunol Today 19 1998 150
3. C.B. Wilson Immunologic basis for increased susceptibility of the neonate to infection J Pediatr 108 1986 1
4. H.R. Hill Biochemical, structural, and functional abnormalities of polymorphonuclear leukocytes in the neonate Pediatr Res 22 1987 375
5. M.S. Cairo, Y. Suen, E. Knoppel, C. van de Ven, A. Nguyen, L. Sender Decreased stimulated GM-CSF production and GM-CSF gene expression but normal numbers of GM-CSF receptors in human term newborns compared with adults Pediatr Res 30 1991 362
6. M.S. Cairo, Y. Suen, E. Knoppel, R. Dana, L. Park, S. Clark, C. van de Ven, L. Sender Decreased G-CSF and IL-3 production and gene expression from mononuclear cells of newborn infants Pediatr Res 31 1992 574
7. M.S. Cairo Therapeutic implications of dysregulated colony-stimulating factor expression in neonates Blood 82 1993 2269
8. Y. Suen, S.M. Lee, J. Schreurs, E. Knoppel, M.S. Cairo Decreased macrophage colony-stimulating factor mRNA expression from activated cord versus adult mononuclear cells altered posttranscriptional stability Blood 84 1994 4269
9. Y. Suen, M. Chang, S.M. Lee, J.S. Buzby, M.S. Cairo Regulation of interleukin-11 protein and mRNA expression in neonatal and adult fibroblasts and endothelial cells Blood 84 1994 4125
10. M. Chang, Y. Suen, S.M. Lee, D. Baly, J.S. Buzby, E. Knoppel, S. Wolpe, M.S. Cairo Transforming growth factor-beta 1, macrophage inflammatory protein-1 alpha, and interleukin-8 gene expression is lower in stimulated human neonatal compared with adult mononuclear cells Blood 84 1994 118
11. S.M. Lee, Y. Suen, L. Chang, V. Bruner, J. Qian, J. Indes, E. Knoppel, C. van de Ven, M.S. Cairo Decreased interleukin-12 (IL-12) from activated cord versus adult peripheral blood mononuclear cells and upregulation of interferon-gamma, natural killer, and lymphokine-activated killer activity by IL-12 in cord blood mononuclear cells Blood 88 1996 945
12. M.S. Cairo, J. Ayello, M. Suri, J. Wu, S. Lillianthal, C. van de Ven IL-12 + IL-18 significantly enhances CB NK and LAK cytotoxicity but is significantly inferior compared to IL-12 + IL-18 induced APB NK+ LAK cytotoxicity implications for differential immune reconstitution and/or graft-vs.-tumor effect post UCBT [abstract] Blood 100 2002 2427
13. J.S. Buzby, E.M. Knoppel, M.S. Cairo Coordinate regulation of Steel factor, its receptor (Kit), and cytoadhesion molecule (ICAM-1 and ELAM-1) mRNA expression in human vascular endothelial cells of differing origins Exp Hematol 22 1994 122
14. M. Chang, Y. Suen, J. Buzby, M. Cairo Thrombopoietic (TPO) mRNA expression by RT-PCR in neonatal endothelial cells and fibroblasts is increased compared to adults implications in the regulation of neonatal thrombopoiesis [abstract] Pediatr Res 37 1995 280a
15. C.B. Wilson, J. Westall, L. Johnston, D.B. Lewis, S.K. Dower, A.R. Alpert Decreased production of interferon-gamma by human neonatal cells. Intrinsic and regulatory deficiencies J Clin Invest 77 1986 860
16. J. Hassan, D.J. Reen Reduced primary antigen-specific T-cell precursor frequencies in neonates is associated with deficient interleukin-2 production Immunology 87 1996 604
17. A. Bertotto, R. Gerli, L. Lanfrancone, S. Crupi, C. Arcangeli, C. Cernetti, F. Spinozzi, P. Rambotti Activation of cord T lymphocytes. II. Cellular and molecular analysis of the defective response induced by anti-CD3 monoclonal antibody Cell Immunol 127 1990 247
18. D.T. Harris, M.J. Schumacher, J. Locascio, F.J. Besencon, G.B. Olson, D. DeLuca, L. Shenker, J. Bard, E.A. Boyse Phenotypic and functional immaturity of human umbilical cord blood T lymphocytes Proc Natl Acad Sci U S A 89 1992 10006
19. R. Foa, M.C. Giubellino, M.T. Fierro, P. Lusso, M.L. Ferrando Immature T lymphocytes in human cord blood identified by monoclonal antibodies a model for the study of the differentiation pathway of T cells in humans Cell Immunol 89 1984 194
20. S. Griffiths-Chu, J.A. Patterson, C.L. Berger, R.L. Edelson, A.C. Chu Characterization of immature T cell subpopulations in neonatal blood Blood 64 1984 296
21. R. Maccario, L. Nespoli, G. Mingrat, A. Vitiello, A.G. Ugazio, G.R. Burgio Lymphocyte subpopulations in the neonate identification of an immature subset of OKT8-positive, OKT3-negative cells J Immunol 130 1983 1129
22. L.T. Clement, P.E. Vink, G.E. Bradley Novel immunoregulatory functions of phenotypically distinct subpopulations of CD4+ cells in the human neonate J Immunol 145 1990 102
23. J. Hassan, D.J. Reen Cord blood CD4+ CD45RA+ T cells achieve a lower magnitude of activation when compared with their adult counterparts Immunology 90 1997 397
24. M.S. Cairo, J.E. Wagner Placental and/or umbilical cord blood an alternative source of hematopoietic stem cells for transplantation Blood 90 1997 4665
25. H. Tanaka, S. Kai, M. Yamaguchi, M. Misawa, Y. Fujimori, M. Yamamoto, H. Hara Analysis of natural killer (NK) cell activity and adhesion molecules on NK cells from umbilical cord blood Eur J Haematol 71 2003 29
26. A. Nagler, L.L. Lanier, S. Cwirla, J.H. Phillips Comparative studies of human FcRIII-positive and negative natural killer cells J Immunol 143 1989 3183
27. C.L. Langrish, J.C. Buddle, A.J. Thrasher, D. Goldblatt Neonatal dendritic cells are intrinsically biased against Th-1 immune responses Clin Exp Immunol 128 2002 118
28. M.M. Hagendorens, D.G. Ebo, A.J. Schuerwegh, A. Huybrechs, H.P. Van Bever, C.H. Bridts, L.S. De Clerck, W.J. Stevens Differences in circulating dendritic cell subtypes in cord blood and peripheral blood of healthy and allergic children Clin Exp Allergy 33 2003 633
29. K.L. Summers, B.D. Hock, J.L. McKenzie, D.N. Hart Phenotypic characterization of five dendritic cell subsets in human tonsils Am J Pathol 159 2001 285
30. F.E. Borras, N.C. Matthews, M.W. Lowdell, C.V. Navarrete Identification of both myeloid CD11c+ and lymphoid CD11c- dendritic cell subsets in cord blood Br J Haematol 113 2001 925
31. R.V. Sorg, G. Kogler, P. Wernet Identification of cord blood dendritic cells as an immature CD11c- population Blood 93 1999 2302
32. M.C. Rissoan, V. Soumelis, N. Kadowaki, G. Grouard, F. Briere, R. de Waal Malefyt, Y.J. Liu Reciprocal control of T helper cell and dendritic cell differentiation Science 283 1999 1183
33. M. Moser, K. Murphy Dendritic cell regulation of Th1-Th2 development Nat Immunol 1 2000 199
34. S. Goriely, B. Vincart, P. Stordeur, J. Vekemans, F. Willems, M. Goldman, D. De Wit Deficient IL-12(p35) gene expression by dendritic cells derived from neonatal monocytes J Immunol 166 2001 2141
35. M.B. Bradley, J. Cai, C. van de Ven, L. Baxi, M.S. Cairo Ex vivo induced (GM-CSF/IL-4/CD40-L) cord blood (CB) vs adult peripheral blood (APB) mature (+CMRF-44) dendritic cells (mDC) exhibit significantly decreased ability to present antigen to CD8+ cytotoxic T lymphocytes (CTL) [abstract] Blood 102 2003 3599
36. S.E. Macatonia, N.A. Hosken, M. Litton, P. Vieira, C.S. Hsieh, J.A. Culpepper, M. Wysocka, G. Trinchieri, K.M. Murphy, A. O'Garra Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells J Immunol 154 1995 5071
37. G. Trinchieri Interleukin-12 a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity Annu Rev Immunol 13 1995 251
38. G. Risdon, J. Gaddy, F.B. Stehman, H.E. Broxmeyer Proliferative and cytotoxic responses of human cord blood T lymphocytes following allogeneic stimulation Cell Immunol 154 1994 14
39. M. Roncarolo, E. Vaccarino, P. Caracco Immunologic properties of umbilical cord blood H. Broxmeyer Cellular characteristics of cord blood and cord blood transplantation 1998 AABB Press Bethesda, MD 67
40. G. Risdon, J. Gaddy, M. Horie, H.E. Broxmeyer Alloantigen priming induces a state of unresponsiveness in human umbilical cord blood T cells Proc Natl Acad Sci U S A 92 1995 2413
41. L.M. Noh, M.M. Khan, K.L. Melmon Suppressive characteristics of the cultured umbilical cord blood lymphocytes enhanced suppression of non specific MLR by short term cultured peripheral blood and rosetted lymphocytes Dev Comp Immunol 12 1988 177
42. H. Ansart-Pirenne, N. Soulimani, E. Tartour, P. Blot, G. Sterkers Defective IL2 gene expression in newborn is accompanied with impaired tyrosine-phosphorylation in T cells Pediatr Res 45 1999 409
43. A.J. Melvin, M.E. McGurn, S.J. Bort, C. Gibson, D.B. Lewis Hypomethylation of the interferon-gamma gene correlates with its expression by primary T-lineage cells Eur J Immunol 25 1995 426
44. J.E. Wagner, J. Kurtzberg Allogeneic umbilical cord blood transplantation J. Winter Blood stem cell transplantation 1997 Kluwer Academic Publishers Norwell, MA 187
45. P. Rubinstein, R.E. Rosenfield, J.W. Adamson, C.E. Stevens Stored placental blood for unrelated bone marrow reconstitution Blood 81 1993 1679
46. K. Ballen, H.E. Broxmeyer, J. McCullough, W. Piaciabello, P. Rebulla, C.M. Verfaillie, J.E. Wagner Current status of cord blood banking and transplantation in the United States and Europe Biol Blood Marrow Transplant 7 2001 635
47. J.K. Fraser, M.S. Cairo, E.L. Wagner, P.R. McCurdy, L.A. Baxter-Lowe, S.L. Carter, N.A. Kernan, M.C. Lill, V. Slone, J.E. Wagner, C.H. Wallas, J. Kurtzberg Cord Blood Transplantation Study (COBLT) cord blood bank standard operating procedures J Hematother 7 1998 521
48. L. Lazzari, C. Corsini, C. Curioni, L. Lecchi, M. Scalamogna, P. Rebulla, G. Sirchia The Milan Cord Blood Bank and the Italian Cord Blood Network J Hematother 5 1996 117
49. K.K. Ballen, J. Hicks, B. Dharan, D. Ambruso, K. Anderson, C. Bianco, L. Bemiller, W. Dickey, R. Lottenberg, M. O'Neill, M. Popovsky, D. Skerrett, I. Sniecinski, J.R. Wingard Racial and ethnic composition of volunteer cord blood donors comparison with volunteer unrelated marrow donors Transfusion 42 2002 1279
50. K.K. Ballen, M. Wilson, J. Wuu, A.M. Ceredona, C. Hsieh, F.M. Stewart, M.A. Popovsky, P.J. Quesenberry Bigger is better maternal and neonatal predictors of hematopoietic potential of umbilical cord blood units Bone Marrow Transplant 27 2001 7
51. D.V. Surbek, B. Schonfeld, A. Tichelli, A. Gratwohl, W. Holzgreve Optimizing cord blood mononuclear cell yield a randomized comparison of collection before vs after placenta delivery Bone Marrow Transplant 22 1998 311
52. L.C. Lasky, T.A. Lane, J.P. Miller, B. Lindgren, H.A. Patterson, N.R. Haley, K. Ballen In utero or ex utero cord blood collection which is better? Transfusion 42 2002 1261
53. American Academy of Pediatrics Work Group on Cord Blood Banking Cord blood banking for potential future transplantation subject review Pediatrics 104 1999 116
54. E. Gluckman, H.A. Broxmeyer, A.D. Auerbach, H.S. Friedman, G.W. Douglas, A. Devergie, H. Esperou, D. Thierry, G. Socie, P. Lehn Hematopoietic reconstitution in a patient with Fanconi's anemia by means of umbilical-cord blood from an HLA-identical sibling N Engl J Med 321 1989 1174
55. E. Gluckman, V. Rocha, A. Boyer-Chammard, F. Locatelli, W. Arcese, R. Pasquini, J. Ortega, G. Souillet, E. Ferreira, J.P. Laporte, M. Fernandez, C. Chastang Eurocord Transplant Group and the European Blood and Marrow Transplantation Group Outcome of cord-blood transplantation from related and unrelated donors N Engl J Med 337 1997 373
56. F. Locatelli, V. Rocha, C. Chastang, W. Arcese, G. Michel, M. Abecasis, C. Messina, J. Ortega, I. Badell-Serra, E. Plouvier, G. Souillet, J.P. Jouet, R. Pasquini, E. Ferreira, F. Garnier, E. Gluckman Eurocord-Cord Blood Transplant Group Factors associated with outcome after cord blood transplantation in children with acute leukemia Blood 93 1999 3662
57. J.E. Wagner, J. Kurtzberg Allogeneic umbilical cord blood transplantation H. Broxmeyer Cellular characteristics of cord blood and cord blood transplantation 1998 AABB Press Bethesda, MD 113
58. E. Gluckman Current status of umbilical cord blood hematopoietic stem cell transplantation Exp Hematol 28 2000 1197
59. F. Locatelli, V. Rocha, W. Reed, F. Bernaudin, M. Ertem, S. Grafakos, B. Brichard, X. Li, A. Nagler, G. Giorgiani, P.R. Haut, J.A. Brochstein, D.J. Nugent, J. Blatt, P. Woodard, J. Kurtzberg, C.M. Rubin, R. Miniero, P. Lutz, T. Raja, I. Roberts, A.M. Will, I. Yaniv, C. Vermylen, N. Tannoia, F. Garnier, I. Ionescu, M.C. Walters, B.H. Lubin, E. Gluckman Related umbilical cord blood transplantation in patients with thalassemia and sickle cell disease Blood 101 2003 2137
60. V. Rocha, J.E. Wagner Jr, K.A. Sobocinski, J.P. Klein, M.J. Zhang, M.M. Horowitz, E. Gluckman Eurocord and International Bone Marrow Transplant Registry Working Committee on Alternative Donor and Stem Cell Sources Graft-versus-host disease in children who have received a cord-blood or bone marrow transplant from an HLA-identical sibling N Engl J Med 342 2000 1846
61. F. Frassoni, M. Podesta, R. Maccario, G. Giorgiani, G. Rossi, M. Zecca, A. Bacigalupo, G. Piaggio, F. Locatelli Cord blood transplantation provides better reconstitution of hematopoietic reservoir compared with bone marrow transplantation Blood 102 2003 1138
62. J.E. Wagner, J. Rosenthal, R. Sweetman, X.O. Shu, S.M. Davies, N.K. Ramsay, P.B. McGlave, L. Sender, M.S. Cairo Successful transplantation of HLA-matched and HLA-mismatched umbilical cord blood from unrelated donors analysis of engraftment and acute graft-versus-host disease Blood 88 1996 795
63. J. Kurtzberg, M. Laughlin, M.L. Graham, C. Smith, J.F. Olson, E.C. Halperin, G. Ciocci, C. Carrier, C.E. Stevens, P. Rubinstein Placental blood as a source of hematopoietic stem cells for transplantation into unrelated recipients N Engl J Med 335 1996 157
64. P. Rubinstein, C. Carrier, A. Scaradavou, J. Kurtzberg, J. Adamson, A.R. Migliaccio, R.L. Berkowitz, M. Cabbad, N.L. Dobrila, P.E. Taylor, R.E. Rosenfield, C.E. Stevens Outcomes among 562 recipients of placental-blood transplants from unrelated donors N Engl J Med 339 1998 1565
65. B.G. Thomson, K.A. Robertson, D. Gowan, D. Heilman, H.E. Broxmeyer, D. Emanuel, P. Kotylo, Z. Brahmi, F.O. Smith Analysis of engraftment, graft-versus-host disease, and immune recovery following unrelated donor cord blood transplantation Blood 96 2000 2703
66. J.E. Wagner, J.N. Barker, T.E. DeFor, K.S. Baker, B.R. Blazar, C. Eide, A. Goldman, J. Kersey, W. Krivit, M.L. MacMillan, P.J. Orchard, C. Peters, D.J. Weisdorf, N.K. Ramsay, S.M. Davies Transplantation of unrelated donor umbilical cord blood in 102 patients with malignant and nonmalignant diseases influence of CD34 cell dose and HLA disparity on treatment-related mortality and survival Blood 100 2002 1611
67. G. Michel, V. Rocha, S. Chevret, W. Arcese, K.W. Chan, A. Filipovich, T.A. Takahashi, M. Vowels, J. Ortega, P. Bordigoni, P.J. Shaw, I. Yaniv, A. Machado, P. Pimentel, F. Fagioli, A. Verdeguer, J.P. Jouet, B. Diez, E. Ferreira, R. Pasquini, J. Rosenthal, E. Sievers, C. Messina, A.P. Iori, F. Garnier, I. Ionescu, F. Locatelli, E. Gluckman Unrelated cord blood transplantation for childhood acute myeloid leukemia a Eurocord Group analysis Blood 102 2003 4290
68. V. Rocha, J. Cornish, E.L. Sievers, A. Filipovich, F. Locatelli, C. Peters, M. Remberger, G. Michel, W. Arcese, S. Dallorso, K. Tiedemann, A. Busca, K.W. Chan, S. Kato, J. Ortega, M. Vowels, A. Zander, G. Souillet, A. Oakill, A. Woolfrey, A.L. Pay, A. Green, F. Garnier, I. Ionescu, P. Wernet, G. Sirchia, P. Rubinstein, S. Chevret, E. Gluckman Comparison of outcomes of unrelated bone marrow and umbilical cord blood transplants in children with acute leukemia Blood 97 2001 2962
69. E. Gluckman, V. Rocha, W. Arcese, G. Michel, G. Sanz, K.W. Chan, T.A. Takahashi, J. Ortega, A. Filipovich, F. Locatelli, S. Asano, F. Fagioli, M. Vowels, A. Sirvent, J.P. Laporte, K. Tiedemann, S. Amadori, M. Abecassis, P. Bordigoni, B. Diez, P.J. Shaw, A. Vora, M. Caniglia, F. Garnier, I. Ionescu, J. Garcia, G. Koegler, P. Rebulla, S. Chevret Factors associated with outcomes of unrelated cord blood transplant guidelines for donor choice Exp Hematol 32 2004 397
70. J. Styczynski, Y.K. Cheung, J. Garvin, D.G. Savage, G.B. Billote, L. Harrison, D. Skerrett, K. Wolownik, C. Wischhover, R. Hawks, M.B. Bradley, G. Del Toro, D. George, D. Yamashiro, C. van de Ven, M.S. Cairo Outcomes of unrelated cord blood transplantation in pediatric recipients Bone Marrow Transplant 34 2004 129
71. P. Rubinstein, C.E. Stevens Placental blood for bone marrow replacement the New York Blood Center's program and clinical results Baillieres Best Pract Res Clin Haematol 13 2000 565
72. J.N. Barker, S.M. Davies, T. DeFor, N.K. Ramsay, D.J. Weisdorf, J.E. Wagner Survival after transplantation of unrelated donor umbilical cord blood is comparable to that of human leukocyte antigen-matched unrelated donor bone marrow results of a matched-pair analysis Blood 97 2001 2957
73. M.J. Laughlin, J. Barker, B. Bambach, O.N. Koc, D.A. Rizzieri, J.E. Wagner, S.L. Gerson, H.M. Lazarus, M. Cairo, C.E. Stevens, P. Rubinstein, J. Kurtzberg Hematopoietic engraftment and survival in adult recipients of umbilical-cord blood from unrelated donors N Engl J Med 344 2001 1815
74. G.F. Sanz, S. Saavedra, D. Planelles, L. Senent, J. Cervera, E. Barragan, C. Jimenez, L. Larrea, G. Martin, J. Martinez, I. Jarque, F. Moscardo, G. Plume, R. Andreu, A.I. Regadera, I. Garcia, S. Molla, P. Solves, J. de La Rubia, P. Bolufer, L. Benlloch, M.A. Soler, M.L. Marty, M.A. Sanz Standardized, unrelated donor cord blood transplantation in adults with hematologic malignancies Blood 98 2001 2332
75. J. Ooi, T. Iseki, S. Takahashi, A. Tomonari, K. Ishii, K. Takasugi, Y. Shimohakamada, N. Ohno, K. Uchimaru, F. Nagamura, A. Tojo, S. Asano Unrelated cord blood transplantation for adult patients with advanced myelodysplastic syndrome Blood 101 2003 4711
76. J. Ooi, T. Iseki, S. Takahashi, A. Tomonari, K. Takasugi, Y. Shimohakamada, T. Yamada, K. Ishii, N. Ohno, F. Nagamura, K. Uchimaru, A. Tojo, S. Asano Unrelated cord blood transplantation for adult patients with de novo acute myeloid leukemia Blood 103 2004 489
77. G.D. Long, M. Laughlin, B. Madan, J. Kurtzberg, C. Gasparetto, A. Morris, D. Rizzieri, C. Smith, J. Vredenburgh, E.C. Halperin, G. Broadwater, D. Niedzwiecki, N.J. Chao Unrelated umbilical cord blood transplantation in adult patients Biol Blood Marrow Transplant 9 2003 772
78. J. Ooi, T. Iseki, S. Takahashi, A. Tomonari, H. Nagayama, K. Ishii, K. Ito, H. Sato, T. Takahashi, M. Shindo, R. Sekine, N. Ohno, K. Uchimaru, F. Nagamura, N. Shirafuji, A. Tojo, K. Tani, S. Asano A clinical comparison of unrelated cord blood transplantation and unrelated bone marrow transplantation for adult patients with acute leukaemia in complete remission Br J Haematol 118 2002 140
79. N.S. Hamza, M. Lisgaris, G. Yadavalli, L. Nadeau, R. Fox, P. Fu, H.M. Lazarus, O.N. Koc, R.A. Salata, M.J. Laughlin Kinetics of myeloid and lymphocyte recovery and infectious complications after unrelated umbilical cord blood versus HLA-matched unrelated donor allogeneic transplantation in adults Br J Haematol 124 2004 488
80. G. Del Toro, P. Satwani, L. Harrison, Y.K. Cheung, M. Brigid Bradley, D. George, D.J. Yamashiro, J. Garvin, D. Skerrett, O. Bessmertny, K. Wolownik, C. Wischhover, C. van de Ven, M.S. Cairo A pilot study of reduced intensity conditioning and allogeneic stem cell transplantation from unrelated cord blood and matched family donors in children and adolescent recipients Bone Marrow Transplant 33 2004 613
81. J.N. Barker, D.J. Weisdorf, T.E. DeFor, B.R. Blazar, J.S. Miller, J.E. Wagner Rapid and complete donor chimerism in adult recipients of unrelated donor umbilical cord blood transplantation after reduced-intensity conditioning Blood 102 2003 1915
82. S. Miyakoshi, K. Yuji, M. Kami, E. Kusumi, Y. Kishi, K. Kobayashi, N. Murashige, T. Hamaki, S.W. Kim, J. Ueyama, S. Mori, S. Morinaga, Y. Muto, S. Masuo, M. Kanemaru, T. Hayashi, Y. Takaue, S. Taniguchi Successful engraftment after reduced-intensity umbilical cord blood transplantation for adult patients with advanced hematological diseases Clin Cancer Res 10 2004 3586
83. K. Yuji, S. Miyakoshi, D. Kato, E. Kusumi, J. Ueyama, S. Morniga, Y. Muto, S. Taniguchi Comparison of outcomes of unrelated bone marrow and umbilical cord blood transplants with reduced-intensity conditioning in adults with hematological diseases results of a matched-pair analysis [abstract] Blood 102 2003 479a
84. S.S. Grewal, J.N. Barker, S.M. Davies, J.E. Wagner Unrelated donor hematopoietic cell transplantation marrow or umbilical cord blood? Blood 101 2003 4233
85. D.L. DiGiusto, R. Lee, J. Moon, K. Moss, T. O'Toole, A. Voytovich, D. Webster, J.J. Mule Hematopoietic potential of cryopreserved and ex vivo manipulated umbilical cord blood progenitor cells evaluated in vitro and in vivo Blood 87 1996 1261
86. L. Pierelli, G. Scambia, A. Fattorossi, G. Bonanno, A. Battaglia, C. Rumi, M. Marone, S. Mozzetti, S. Rutella, G. Menichella, V. Romeo, S. Mancuso, G. Leone Functional, phenotypic and molecular characterization of cytokine low-responding circulating CD34+ haemopoietic progenitors Br J Haematol 102 1998 1139
87. A. Rice, C. Flemming, J. Case, J. Stevenson, L. Gaudry, M. Vowels Comparative study of the in vitro behavior of cord blood subpopulations after short-term cytokine exposure Bone Marrow Transplant 23 1999 211
88. J. Zhang, R. Brown, M. Heye, S. Welhausen, A. Nett, C. Burke, R.H. Herzig Optimization of ex vivo expansion conditions with different growth factor combinations and concentrations maintaining long term engrafting ability of umbilical cord blood CD34+ stem cells [abstract] Biol Blood Marrow Transplant 10 2004 80
89. I.D. Lewis, C.M. Verfaillie Multi-lineage expansion potential of primitive hematopoietic progenitors superiority of umbilical cord blood compared to mobilized peripheral blood Exp Hematol 28 2000 1087
90. I.D. Lewis, G. Almeida-Porada, J. Du, I.R. Lemischka, K.A. Moore, E.D. Zanjani, C.M. Verfaillie Umbilical cord blood cells capable of engrafting in primary, secondary, and tertiary xenogeneic hosts are preserved after ex vivo culture in a noncontact system Blood 97 2001 3441
91. I. McNiece, D. Kubegov, P. Kerzic, E.J. Shpall, S. Gross Increased expansion and differentiation of cord blood products using a two-step expansion culture Exp Hematol 28 2000 1181
92. S.L. Staba, K.B. Crapnell, J.G. Hall, M. Reese, J. Kurtzberg Ex vivo expansion of immature and mature T cells derived from umbilical cord blood (UCB) [abstract] Biol Blood Marrow Transplant 10 2004 16
93. K.L. Robinson, J. Ayello, R. Hughes, C. van de Ven, L. Issitt, J. Kurtzberg, M.S. Cairo Ex vivo expansion, maturation, and activation of umbilical cord blood-derived T lymphocytes with IL-2, IL-12, anti-CD3, and IL-7. Potential for adoptive cellular immunotherapy post-umbilical cord blood transplantation Exp Hematol 30 2002 245
94. + bright/dim subsets expressing increased inhibitory receptors from cryopreserved/thawed/expanded/recryopreserved/ rethawed/expanded (CTCTE) umbilical cord blood (UCB) using anti-CD3, IL-2, IL-7 and IL-12(AB/CY) [abstract] Biol Blood Marrow Transplant 10 2004 16
95. P.H. Shaw, D. Gilligan, X.M. Wang, P.F. Thall, S.J. Corey Ex vivo expansion of megakaryocyte precursors from umbilical cord blood CD34 cells in a closed liquid culture system Biol Blood Marrow Transplant 9 3 2003 151
96. W. Piacibello, F. Sanavio, A. Severino, A. Dane, L. Gammaitoni, F. Fagioli, E. Perissinotto, G. Cavalloni, O. Kollet, T. Lapidot, M. Aglietta Engraftment in nonobese diabetic severe combined immunodeficient mice of human CD34(+) cord blood cells after ex vivo expansion evidence for the amplification and self-renewal of repopulating stem cells Blood 93 1999 3736
97. G. Guenechea, J.C. Segovia, B. Albella, M. Lamana, M. Ramirez, C. Regidor, M.N. Fernandez, J.A. Bueren Delayed engraftment of nonobese diabetic/severe combined immunodeficient mice transplanted with ex vivo-expanded human CD34(+) cord blood cells Blood 93 1999 1097
98. J. Jaroscak, K. Goltry, A. Smith, B. Waters-Pick, P.L. Martin, T.A. Driscoll, R. Howrey, N. Chao, J. Douville, S. Burhop, P. Fu, J. Kurtzberg Augmentation of umbilical cord blood (UCB) transplantation with ex vivo-expanded UCB cells results of a phase 1 trial using the AastromReplicell System Blood 101 2003 5061
99. E.J. Shpall, R. Quinones, R. Giller, C. Zeng, A.E. Baron, R.B. Jones, S.I. Bearman, Y. Nieto, B. Freed, N. Madinger, C.J. Hogan, V. Slat-Vasquez, P. Russell, B. Blunk, D. Schissel, E. Hild, J. Malcolm, W. Ward, I.K. McNiece Transplantation of ex vivo expanded cord blood Biol Blood Marrow Transplant 8 2002 368
100. J. Kurtzberg, E.L. Wagner, J.K. Fraser, M. Cairo, L. Jensen, G. Cohen, S.L. Carter, N.A. Kernan Results of the cord blood transplantation study (COBLT) unrelated donor banking program from donor screening to characterization of banked units [abstract] Blood 102 2003 1680
101. M.S. Cairo, G. Cohen, E.L. Wagner, J.K. Fraser, L. Jensen, S.L. Carter, N. Kernan Unrelated cord blood (CB) banking, immune lymphocyte subsets and nucleated RBC characterization and correlation with ethnicity, birthweight, sex and type of delivery a report from the COBLT/NHLBI program [abstract] Exp Hematol 32 2004 198