Design and optimization of a chemometrics-assisted spectrophotometric method for the simultaneous determination of levodopa and carbidopa in pharmaceutical products

Analytica Chimica Acta

Volumn 543, Issue 1-2, 2005, Pages 192-198

  Damiani, Patricia C ^a   Moschetti, Andrea C ^a   Rovetto, Adrián J ^a   Benavente, Fernando ^b   Olivieri, Alejandro C ^a  

^a UNIVERSIDAD NACIONAL DE ROSARIO   (Argentina)

^b UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Carbidopa; Levodopa; Partial least squares; Spectrophotometry

Indexed keywords

AMINES; AMINO ACIDS; CALIBRATION; DISEASES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MATHEMATICAL MODELS; OPTIMIZATION; SPECTROPHOTOMETRY; STATISTICAL METHODS;

CHEMOMETRICS-ASSISTED SPECTROPHOTOMETRIC METHOD; LEVODOPA; PARKINSON'S DISEASE; PHARMACOPOEIA METHOD;

DRUG PRODUCTS;

CARBIDOPA; DECARBOXYLASE INHIBITOR; DOPAMINE; LEVODOPA; NEUROTRANSMITTER; OXIDIZING AGENT; PERIODATE; POTASSIUM DERIVATIVE; POTASSIUM PERIODATE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CALIBRATION; CHEMOMETRICS; DRUG DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PARKINSON DISEASE; PREDICTION; PRIORITY JOURNAL; REGRESSION ANALYSIS; SPECTROPHOTOMETRY; STATISTICAL ANALYSIS; VALIDATION PROCESS;

EID: 20444395469     PISSN: 00032670     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aca.2005.04.065     Document Type: Article

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