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Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 13, 2005, Pages 3292-3295

Discovery and synthesis of a novel and selective drug-like P2X1 antagonist

(6) Jaime Figueroa, S a Greenhouse, R a Padilla, F a Dillon, M P a Gever, J R a Ford, A P D W a

a ROCHE BIOSCIENCE (United States)

Author keywords

P2X1 antagonist

Indexed keywords

1H BENZOIMIDAZOLE 2 CARBOXYLIC ACID [1 (1 CYCLOHEXYLMETHYL 3 CYCLOPROPYL 2,3 DIHYDROXYPROPYLCARBAMOYL) 2 THIAZOL 4 YLETHYL]AMIDE; PURINE P2X1 RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; FEMALE; NONHUMAN; RECEPTOR BINDING;

AMIDES; ANIMALS; CALCIUM; CELL LINE; CELL SURVIVAL; HUMANS; INHIBITORY CONCENTRATION 50; LIGANDS; RECEPTORS, PURINERGIC P2; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

ANIMALIA;

EID: 20444383141 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2005.04.049 Document Type: Article

Times cited : (23)

References (9)

1
- 0036788971
- A.R. North Physiol. Rev. 82 2002 1013
- (2002) Physiol. Rev. , vol.82 , pp. 1013
- North, A.R.¹

2
- 33646212988
- D.A. Cockayne, P.M. Dunn, G. Burnstock, and A.P.D.W. Ford Soc. Neurosci. Abstr. 28 2002 5212
- (2002) Soc. Neurosci. Abstr. , vol.28 , pp. 5212
- Cockayne, D.A.¹ Dunn, P.M.² Burnstock, G.³ Ford, A.P.D.W.⁴

3
- 0034718839
- D.A. Cockayne, S.G. Hamilton, Q.-M. Zhu, P.M. Dunn, S. Novakovic, A.B. Malmberg, G. Cain, A. Berson, L. Kassotakis, L. Hedley, W.G. Lachnit, G. Burnstock, S.B. McMahon, and A.P.D.W. Ford Nature 407 2000 1011
- (2000) Nature , vol.407 , pp. 1011
- Cockayne, D.A.¹ Hamilton, S.G.² Zhu, Q.-M.³ Dunn, P.M.⁴ Novakovic, S.⁵ Malmberg, A.B.⁶ Cain, G.⁷ Berson, A.⁸ Kassotakis, L.⁹ Hedley, L.¹⁰ Lachnit, W.G.¹¹ Burnstock, G.¹² McMahon, S.B.¹³ Ford, A.P.D.W.¹⁴

4
- 3042697198
- G. Burnstock, B.F. King, I.D. Knowles, and A.G. Ramage Br. J. Pharmacol. 142 2004 519 In this paper 1 is identified as RO116-6446/008
- (2004) Br. J. Pharmacol. , vol.142 , pp. 519
- Burnstock, G.¹ King, B.F.² Knowles, I.D.³ Ramage, A.G.⁴

5
- 1842557492
- M.U. Kassack, K. Braun, M. Ganso, H. Ullmann, P. Nickel, B. Böing, G. Müller, and G. Lambrecht Eur. J. Med. Chem. 39 2004 345
- (2004) Eur. J. Med. Chem. , vol.39 , pp. 345
- Kassack, M.U.¹ Braun, K.² Ganso, M.³ Ullmann, H.⁴ Nickel, P.⁵ Böing, B.⁶ Müller, G.⁷ Lambrecht, G.⁸

6
- 20444425916
- Branca, Q.; Neidhart, W.; Ramuz, H.; Stadler, H.; Wostl, W. Eur. Pat. Appl. EP 0416373, 1991
- Branca, Q.; Neidhart, W.; Ramuz, H.; Stadler, H.; Wostl, W. Eur. Pat. Appl. EP 0416373, 1991

7
- 0030462372
- M.A. Schwindt, D.T. Belmont, M. Carlson, L.C.S. Franklin, V.S. Hendrickson, G.L. Karrick, R.W. Poe, D.M. Sobieray, and J. Vande Vusse J. Org. Chem. 61 1996 9564
- (1996) J. Org. Chem. , vol.61 , pp. 9564
- Schwindt, M.A.¹ Belmont, D.T.² Carlson, M.³ Franklin, L.C.S.⁴ Hendrickson, V.S.⁵ Karrick, G.L.⁶ Poe, R.W.⁷ Sobieray, D.M.⁸ Vande Vusse, J.⁹

8
- 84970031051
- H. Schmidbaur, A. Schier, and U. Schubert Chem. Ber. 116 1983 1938
- (1983) Chem. Ber. , vol.116 , pp. 1938
- Schmidbaur, H.¹ Schier, A.² Schubert, U.³

9
- 0025014627
- J. Coste, D. Le-Nguyen, and B. Castro Tetrahedron Lett. 31 1990 205
- (1990) Tetrahedron Lett. , vol.31 , pp. 205
- Coste, J.¹ Le-Nguyen, D.² Castro, B.³

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