Are unconventional NMDA receptors involved in slowly adapting type I mechanoreceptor responses?

Neuroscience

Volumn 133, Issue 3, 2005, Pages 763-773

  Cahusac, P M B ^a   Senok, S S ^b   Hitchcock, I S ^c   Genever, P G ^c   Baumann, K I ^d  

^a UNIVERSITY OF STIRLING   (United Kingdom)

^b ARABIAN GULF UNIVERSITY   (Bahrain)

^c UNIVERSITY OF YORK   (United Kingdom)

^d UNIVERSITY OF HAMBURG   (Germany)

Author keywords

Glutamate; Ifenprodil; Mechanogated channels; Merkel cell; NR1; NR2A B

Indexed keywords

6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; 6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; AMPA RECEPTOR ANTAGONIST; DIZOCILPINE; IFENPRODIL; IONOTROPIC RECEPTOR ANTAGONIST; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MECHANORECEPTOR; MERKEL CELL; NERVE ENDING; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; GLUTAMIC ACID; MERKEL CELLS; MICROSCOPY, ELECTRON; RATS; RATS, WISTAR; RECEPTORS, AMPA; RECEPTORS, KAINIC ACID; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPTIC TRANSMISSION; VIBRISSAE;

EID: 20444366908     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2005.03.018     Document Type: Article

References (35)

1. C.P. Bath, L.N. Farrell, J. Gilmore, M.A. Ward, C.A. Hicks, M.J. O'Neill, D. Bleakman The effects of ifenprodil and eliprodil on voltage-dependent Ca2+ channels and in gerbil global cerebral ischaemia Eur J Pharmacol 299 1996 103 112
2. K.I. Baumann, E. Chan, Z. Halata, S.S. Senok, W.H. Yung An isolated rat vibrissal preparation with stable responses of slowly adapting mechanoreceptors Neurosci Lett 213 1996 1 4
3. K.I. Baumann, S.S. Senok Transduction in Merkel cell mechanoreceptors What is the job of the Merkel cell? K.I. Baumann Z. Halata I. Moll The Merkel cell structure, development, function, cancerogenesis 2003 Springer Berlin 169 176
4. C.A. Briggs, D.G. McKenna Effect of MK-801 at the human [α]7 nicotinic acetylcholine receptor Neuropharmacology 35 1996 407 414
5. P.M.B. Cahusac Are glutamate receptors involved in transmission at the junction between Merkel cell and nerve terminal? K.I. Baumann Z. Halata I. Moll The Merkel cell structure, development, function, cancerogenesis 2003 Springer Berlin 155 162
6. M. Casado, P. Ascher Opposite modulation of NMDA receptors by lysophospholipids and arachidonic acid common features with mechanosensitivity J Physiol Lond 513 1998 317 330
7. B.L. Chenard, F.S. Menniti Antagonists selective for NMDA receptors containing the NR2B subunit Curr Pharm Des 5 1999 381 404
8. S. Cull-Candy, S. Brickley, M. Farrant NMDA receptor subunits diversity, development and disease Curr Opin Neurobiol 11 2001 327 335
9. J. Diamond, L.R. Mills, K.M. Mearow Evidence that the Merkel cell in not the transducer in the mechanosensory Merkel cell-neurite complex Prog Brain Res 74 1988 51 56
10. R. Dingledine, K. Borges, D. Bowie, S.F. Traynelis The glutamate receptor ion channels Pharmacol Rev 51 1999 7 61
11. S. Ebara, K. Kumamoto, T. Matsuura, J.E. Mazurkiewicz, F.L. Rice Similarities and differences in the innervation of mystacial vibrissal follicle-sinus complexes in the rat and cat A confocal microscopic study J Comp Neurol 449 2002 103 119
12. B.M. Fagan, P.M.B. Cahusac Evidence for glutamate receptor mediated transmission at mechanoreceptors in the skin Neuroreport 12 2001 341 347
13. G. Fischer, V. Mutel, G. Trube, P. Malherbe, J.N.C. Kew, E. Mohacsi, M.P. Heitz, J.A. Kemp Ro 25-6981, a highly potent and selective blocker of N-methyl- D-aspartate receptors containing the NR2B subunit. Characterization in vitro J Pharmacol Exp Ther 283 1997 1285 1292
14. R.F. Genovese, X.C.M. Lu Effects of MK-801 stereoisomers on schedule-controlled behavior in rats Psychopharmacology 105 1991 477 480
15. H. Haeberle, M. Fujiwara, J. Chuang, M.M. Medina, M.V. Panditrao, S. Bechstedt, J. Howard, E.A. Lumpkin Molecular profiling reveals synaptic release machinery in Merkel cells Proc Natl Acad Sci U S A 101 2004 14503 14508
16. Z. Halata, M. Grim, K.I. Bauman Friedrich Sigmund Merkel and his "Merkel cell," morphology, development, and physiology Review and new results Anat Rec A Discov Mol Cell Evol Biol 271A 2003 225 239
17. L. He, R.P. Tuckett, K.B. English 5-HT2 and 3 receptor antagonists suppress the response of rat type I slowly adapting mechanoreceptor an in vitro study Brain Res 969 2003 230 236
18. I.S. Hitchcock, P.G. Genever, P.M.B. Cahusac Essential components for a glutamatergic synapse between Merkel cell and nerve terminal in rats Neurosci Lett 362/3 2004 196 199
19. A. Iggo, G.S. Findlater A review of Merkel cell mechanisms W. Hamann A. Iggo Sensory receptor mechanisms 1984 World Scientific Publishing Co Singapore 117 131
20. A. Iggo, A.R. Muir The structure and function of a slowly adapting touch corpuscle in hairy skin J Physiol (Lond) 200 1969 763 796
21. D. Jane Pharmacology of NMDA receptors J. Egebjerg A. Schousboe P. Krogsgaard-Larsen Glutamate and GABA receptors and transporters 2002 Taylor & Francis London 69 98
22. V. Mutel, D. Buchy, A. Klingelschmidt, J. Messer, Z. Bleuel, J.A. Kemp, J.G. Richards In vitro binding properties in rat brain of [H-3]Ro 25-6981, a potent and selective antagonist of NMDA receptors containing NR2B subunits J Neurochem 70 1998 2147 2155
23. M.G. Nunzi, A. Pisarek, E. Mugnaini Merkel cells, corpuscular nerve endings and free nerve endings in the mouse palatine mucosa express three subtypes of vesicular glutamate transporters J Neurocytol 33 2004 359 376
24. H. Ogawa The Merkel cell as a possible mechanoreceptor cell Prog Neurobiol 49 1996 317 334
25. P. Paoletti, P. Ascher Mechanosensitivity of NMDA receptors in cultured mouse central neurons Neuron 13 1994 645 655
26. P. Paoletti, P. Ascher, J. Neyton High-affinity zinc inhibition of NR1-NR2A receptors J Neurosci 17 1997 5711 5725
27. A.S. Ramoa, M. Alkondon, Y. Aracava, J. Irons, G.G. Lunt, S.S. Deshpande, S. Wonnacott, R.S. Aronstam, E.X. Albuquerque The anticonvulsant MK-801 interacts with peripheral and central nicotinic acetylcholine-receptor ion channels J Pharmacol Exp Ther 254 1990 71 82
28. F.L. Rice, E. Kinnman, H. Aldskogius, O. Johansson, J. Arvidsson The innervation of the mystacial pad of the rat as revealed by PGP 9.5 immunofluorescence J Comp Neurol 337 1993 366 385
29. J.N. Sengupta, J. Petersen, S. Peles, R. Shaker Response properties of antral mechanosensitive afferent fibers and effects of ionotropic glutamate receptor antagonists Neuroscience 125 2004 711 723
30. S.S. Senok, P.G. Genever, P.M.B. Cahusac, K.I. Baumann Glutamate receptor-like immunoreactivity in rat vibrissal Merkel cells K.I. Baumann Z. Halata I. Moll The Merkel cell structure, development, function, cancerogenesis 2003 Springer Berlin 163 168
31. T. Tachibana The Merkel cell Recent findings and unresolved problems Arch Histol Cytol 58 1995 379 396
32. G. Trube, P. Ehrhard, P. Malherbe, G. Huber The selectivity of Ro 25-6981 for NMDA receptor subtypes expressed in Xenopus oocytes Soc Neurosci Abstr 22 1996 693.4
33. 2+ antagonize NMDA and GABA responses of hippocampal neurons Nature 328 1987 640 643
34. M. Wyszynski, J. Lin, A. Rao, E. Nigh, A.H. Beggs, A.M. Craig, M. Sheng Competitive binding of alpha-actinin and calmodulin to the NMDA receptor Nature 385 1997 439 442
35. Y. Yamashita, H. Ogawa Slowly adapting cutaneous mechanoreceptor afferent units associated with Merkel cells in frogs and effects of direct currents Somatosens Mot Res 8 1991 87 95