QSAR studies on adenosine kinase inhibitors

Medicinal Chemistry Research

Volumn 13, Issue 6-7, 2004, Pages 479-496

  Agrawal, Vijay K ^a   Singh, Kamana ^a   Khadikar, Padmakar V ^b  

^a A P S UNIVERSITY   (India)

^b Laxmi Pest and Fumigation Pvt Ltd   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE KINASE INHIBITOR; PYRROLO[2,3 D]PYRIMIDINE DERIVATIVE;

CONFERENCE PAPER; CORRELATION ANALYSIS; DRUG STRUCTURE; ELECTRONEGATIVITY; ENZYME INHIBITION; EPILEPSY; HYDROGEN BOND; IC 50; INFLAMMATION; ISCHEMIA; PAIN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REGRESSION ANALYSIS; VALIDATION PROCESS;

EID: 20344396876     PISSN: 10542523     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00044-004-0048-0     Document Type: Conference Paper

References (33)

1. Ramsden, C. A., Ed., Comprehensive Medicinal Chemistry, Pergamon, Oxford, 1990, Vol.4.
2. Cronstein, B.N.; Naine, D.; Firestein, G. Arthritis Rheum. 1995, 38, 1040.
3. Jiang, N.; Kowaluk, E.A.; Lee, C. H. Mazdiyasni, H.; Chopp, M. Eur. J. Pharmacol. 1997, 320, 131.
4. Jarvis, N.F.; Yu, H.; Kohlhaas, K.; Alexander, K.; Lee, C.H.; Jiang, N.; Bhagwat, S.; Williams, N.; Kowaluk, E.A. J. Pharmacol.Exp.Ther. 2000, 295, 1156.
5. Kier, L. B.; Hall, L. H. Molecular Connectivity in Structure-Activity Relationship, Wiley, New York, 1986.
6. Kier, L. B.; Hall, L. H. Molecular Structure Description, Academic Press, New York, 1999.
7. Trinajstic, N.; Chemical Graph Theory, (CRC Press, Boca Raton) Fl., 1992.
8. Todeschini, R.; Consonni,V. Handbook of Molecular Descriptors, Wiley-VCH, Weinheim(GER),2000.
9. Devillers, J.; Balaban, A.T. Topological Indices and Related Descriptors in QSAR and QSPR, Gorden & Breach, Williston, VT, 2000, 40, 245
10. Karelson, M. Molecular Descriptors in QSAR/QSPR, J. Wiley & Sons, New York, 2000.
11. Pauling, L. The Nature of the Chemical Bond, Cornell Univ. Press, Ithaca, New York, 1960.
12. Khadikar, P.V.; Lukovits, I.; Agrawal, V.K.; Shrivastva, S.; Jaiswal, M.; Gutman, I.; Karmarkar, S.; Shrivastava, A. Indian J. Chem., 2003, 42A, 1436.
13. Agrawal, V.K.; Khadikar, P.V. Bioorg. Med. Chem., 2002, 10, 3517.
14. Agrawal, V.K.; Joseph, S.; Khadikar, P.V.; Karmarkar, S. Acta Pharm. 2000, 50, 329.
15. Agrawal, V.K.; Mishra, K.; Khadikar, P.V. Oxidation Commun. 2003, 26, 14.
16. Wiener, H. J. Am. Chem. Soc., 1941, 69, 17.
17. Balaban, A. T. Chem. Phys. Lett., 1982, 89, 399.
18. Khadikar, P.V.; Sharma, S.; Sharma, V.; Joshi, S.; Lukovits, I.; Kaveeshwar, M.; Bull. Soc.Chem.Belg. 1997, 106, 767.
19. Randic, M. J. Am. Chem Soc., 1975, 97, 6609.
20. Randic, M. J. Mol. Graphics Model, 2001, 20, 19.
21. Gutman, I. Graph Theory Notes New York 1994, 27, 9-17.
22. Khadikar, P.V.; Deshpandey, N.V.; Kale, P.P.; Dubrynin, A.; Gutman, I.; Domotor, G. J. Chem. Inf. Comput. Sci. 1995, 35, 547-550.
23. Ugarkar, B.G.; Da Re, J.A.; Kopcho, J.J.; Browne, C.E.; Schanzer, J.M.; Wiesner, J.B.; Erion, M.D. J.Med. Chem., 2000, 43, 2883.
24. Balaban A. T. (Ed.), From Chemical Topology to Three-Dimensional Geometry, Plenum, New York, 1997.
25. Agrawal, V.K.; Singh, J.; Khadikar, P.V. Bioorg. Med. Chem., 2002, 10, 3981.
26. Agrawal, V.K.; Sharma, R.; Khadikar, P.V.; Bioorg. Med. Chem., 2002, 10, 2993.
27. Agrawal, V.K.; Sohgaura, R.; Khadikar, P.V.; Bioorg. Med. Chem., 2001, 9, 3295.
28. Agrawal, V.K.; Khadikar, P.V. Bioorg. Med. Chem. 2002, 10, 3517.
29. Agrawal, V.K.; Singh J.; Khadikar, P.V. Bioorg. Med. Chem. 2002, 10, 3981.
30. Agrawal, V.K.; Karmarkar, S.; Khadikar, P.V.; Shrivastva, S.; Lukovits, I. Ind. J. Chem 2003, 42A, 1426.
31. Chaterjee, S.; Hadi, A.S.; Price, B. Regression Analysis by Examples, 3rd Ed. Wiley: New York, 2000.
32. Pogliani, L.; Amino Acids., 1994, 6, 141.
33. Pogliani, L.; J. Phys. Chem. 1996, 100, 18065.