Generation and characterization of monoclonal antibodies to human PCTAIRE 3

Hybridoma

Volumn 24, Issue 2, 2005, Pages 98-105

  Herskovits, A Z ^a   Davies, P ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 1; EPITOPE; ISOPROTEIN; MONOCLONAL ANTIBODY; PROTEIN KINASE; PROTEIN PCTAIRE 1; PROTEIN PCTAIRE 2; PROTEIN PCTAIRE 3; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ANTIBODY SPECIFICITY; ARTICLE; CONTROLLED STUDY; CROSS REACTION; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITOPE MAPPING; GENETIC TRANSFECTION; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SEQUENCE HOMOLOGY; WESTERN BLOTTING;

EID: 20344396128     PISSN: 15540014     EISSN: None     Source Type: Journal    
DOI: 10.1089/hyb.2005.24.98     Document Type: Article

References (15)

1. Okuda T, Cleveland JL, and Downing JR: PCTAIRE-1 and PCTAIRE-3, two members of a novel cdc2/CDC28-related protein kinase gene family. Oncogene 1992;7:2249-2258.
2. Meyerson M, Enders GH, Wu CL, Su LK, Gorka C, Nelson C, Harlow E, and Tsai LH: A family of human cdc2-related protein kinases. Embo J 1992;11:2909-2917.
3. Graeser R, Gannon J, Poon RY, Dubois T, Aitken A, and Hunt T: Regulation of the CDK-related protein kinase PCTAIRE-1 and its possible role in neurite outgrowth in Neuro-2A cells. J Cell Sci 2002;115:3479-3490.
4. Sladeczek F, Camonis JH, Burnol AF, and Le Bouffant F: The Cdk-like protein PCTAIRE-1 from mouse brain associates with p11 and 14-3-3 proteins. Mol Gen Genet 1997;254:571-577.
5. Le Bouffant F, Le Minier P, Traiffort E, Ruat M, and Sladeczek F: Multiple subcellular localizations of PCTAIRE-1 in brain. Mol Cell Neurosci 2000;16:388-395.
6. Le Bouffant F, Capdevielle J, Guillemot JC, and Sladeczek F: Characterization of brain PCTAIRE-1 kinase immunoreactivity and its interactions with p11 and 14-3-3 proteins. Eur J Biochem 1998;257:112-120.
7. Khawaja X, Xu J, Liang JJ, and Barrett JE: Proteomic analysis of protein changes developing in rat hippocampus after chronic antidepressant treatment: implications for depressive disorders and future therapies. J Neurosci Res 2004;75:451-460.
8. Hirose T, Kawabuchi M, Tamaru T, Okumura N, Nagai K, and Okada M: Identification of tudor repeat associator with PCTAIRE 2 (Trap). A novel protein that interacts with the N-terminal domain of PCTAIRE 2 in rat brain. Eur J Biochem 2000;267:2113-2121.
9. Hirose T, Tamaru T, Okumura N, Nagai K, and Okada M: PCTAIRE 2, a Cdc2-related serine/threonine kinase, is predominantly expressed in terminally differentiated neurons. Eur J Biochem 1997;249:481-488.
10. Herskovits AZ, and Davies P: Cloning and expression analysis of two novel PCTAIRE 3 transcripts from human brain. Gene 2004;328:59-67.
11. Gao CY, Chauthaiwale VM, Rampalli AM, and Zelenka PS: Expression of alternatively spliced PCTAIRE-1 mRNA in PC12 cells and neonatal rat brain. Gene 1996;176:243-247.
12. Besset V, Rhee K, and Wolgemuth DJ: The cellular distribution and kinase activity of the Cdk family member Pctaire1 in the adult mouse brain and testis suggest functions in differentiation. Cell Growth Differ 1999;10:173-181.
13. Cheng K, Li Z, Fu WY, Wang JH, Fu AK, and Ip NY: Pctaire1 interacts with p35 and is a novel substrate for Cdk5/p35. J Biol Chem 2002;277:31988-31993.
14. Rhee K, and Wolgemuth DJ: Cdk family genes are expressed not only in dividing but also in terminally differentiated mouse germ cells, suggesting their possible function during both cell division and differentiation. Dev Dyn 1995;204:406-420.
15. Palmer KJ, Konkel J, and Stephens DJ: Regulation of ER export by PCTAIRE protein kinases. Presented at the Biochemical Society Annual Symposium, Glasgow, UK, 2004.