메뉴 건너뛰기




Volumn 2, Issue 2, 2005, Pages 96-102

Technology insight: Calprotectin, lactoferrin and nitric oxide as novel markers of inflammatory bowel disease

Author keywords

Calprotectin; Fecal marker; Inflammatory bowel disease; Lactoferrin; Nitric oxide

Indexed keywords

AZATHIOPRINE; CALPROTECTIN; GLUCOCORTICOID; INFLIXIMAB; LACTOFERRIN; MESALAZINE; NITRIC OXIDE; SALAZOSULFAPYRIDINE;

EID: 20344382725     PISSN: 17434378     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncpgasthep0094     Document Type: Review
Times cited : (60)

References (52)
  • 1
    • 0035847652 scopus 로고    scopus 로고
    • Cost-effectiveness of endoscopy in irritable bowel syndrome
    • Suleiman S and Sonnenberg A (2001) Cost-effectiveness of endoscopy in irritable bowel syndrome. Arch Intern Med 161: 369-375
    • (2001) Arch. Intern. Med. , vol.161 , pp. 369-375
    • Suleiman, S.1    Sonnenberg, A.2
  • 2
    • 0022621499 scopus 로고
    • Indium 111-granulocyte scanning in the assessment of disease extend and disease activity in inflammatory bowel disease. A comparison with colonoscopy, histology, and fecal indium 111-granulocyte excretion
    • Saverymuttu SH et al. (1986) Indium 111-granulocyte scanning in the assessment of disease extend and disease activity in inflammatory bowel disease. A comparison with colonoscopy, histology, and fecal indium 111-granulocyte excretion. Gastroenterology 90: 1121-1128
    • (1986) Gastroenterology , vol.90 , pp. 1121-1128
    • Saverymuttu, S.H.1
  • 3
    • 0029869589 scopus 로고    scopus 로고
    • Review article: Quantitative leucocyte scanning in the assessment of inflammatory bowel disease activity and its response to therapy
    • Weldon MJ et al. (1996) Review article: quantitative leucocyte scanning in the assessment of inflammatory bowel disease activity and its response to therapy. Aliment Pharmacol Ther 10: 123-132
    • (1996) Aliment. Pharmacol. Ther. , vol.10 , pp. 123-132
    • Weldon, M.J.1
  • 4
    • 0022631955 scopus 로고
    • Clinical remission in Crohn's disease-assessment using faecal 111 in granulocyte excretion
    • Saverymuttu SH (1986) Clinical remission in Crohn's disease-assessment using faecal 111 in granulocyte excretion. Digestion 33: 74-79
    • (1986) Digestion , vol.33 , pp. 74-79
    • Saverymuttu, S.H.1
  • 5
    • 0141651527 scopus 로고    scopus 로고
    • Review article: The incidence and prevalence of colorectal cancer in inflammatory bowel disease
    • Munkholm P (2003) Review article: the incidence and prevalence of colorectal cancer in inflammatory bowel disease. Aliment Pharmacol Ther 18 (Suppl 2): 1-5
    • (2003) Aliment. Pharmacol. Ther. , vol.18 , Issue.SUPPL. 2 , pp. 1-5
    • Munkholm, P.1
  • 6
    • 0030888894 scopus 로고    scopus 로고
    • Healing of severe recurrent ileitis with azathioprine therapy in patients with Crohn's disease
    • D'Haens G et al. (1997) Healing of severe recurrent ileitis with azathioprine therapy in patients with Crohn's disease. Gastroenterology 112: 1475-1481
    • (1997) Gastroenterology , vol.112 , pp. 1475-1481
    • D'Haens, G.1
  • 7
    • 0032723990 scopus 로고    scopus 로고
    • Endoscopic and histologic healing of Crohn's (ileo-) colitis with azathioprine
    • D'Haens G et al. (1999) Endoscopic and histologic healing of Crohn's (ileo-) colitis with azathioprine. Gastrointest Endosc 50: 667-671
    • (1999) Gastrointest. Endosc. , vol.50 , pp. 667-671
    • D'Haens, G.1
  • 8
    • 0035166741 scopus 로고    scopus 로고
    • Clinical, biological, and histologic parameters as predictors relapse in ulcerative colitis
    • Bitton A et al. (2001) Clinical, biological, and histologic parameters as predictors relapse in ulcerative colitis. Gastroenterology 120: 13-20
    • (2001) Gastroenterology , vol.120 , pp. 13-20
    • Bitton, A.1
  • 9
    • 0027930780 scopus 로고
    • Endoscopic management of inflammatory bowel disease
    • Modigliani R (1994) Endoscopic management of inflammatory bowel disease. Am J Gastroenterol 89 (Suppl 8): S53-S65
    • (1994) Am. J. Gastroenterol. , vol.89 , Issue.SUPPL. 8
    • Modigliani, R.1
  • 10
    • 0035127074 scopus 로고    scopus 로고
    • Comparative study of ASCA (anti- Saccharomyces cerevisiae antibody) assays in inflammatory bowel disease
    • Vermeire S et al. (2001) Comparative study of ASCA (anti- Saccharomyces cerevisiae antibody) assays in inflammatory bowel disease. Gastroenterology 120: 827-33
    • (2001) Gastroenterology , vol.120 , pp. 827-833
    • Vermeire, S.1
  • 11
    • 0034887447 scopus 로고    scopus 로고
    • Evaluation of serologic disease markers in a population-based cohort of patients with ulcerative colitis and Crohn's disease
    • Sandborn WJ et al. (2001) Evaluation of serologic disease markers in a population-based cohort of patients with ulcerative colitis and Crohn's disease. Inflamm Bowel Dis 7: 192-201
    • (2001) Inflamm. Bowel Dis. , vol.7 , pp. 192-201
    • Sandborn, W.J.1
  • 12
    • 0036113795 scopus 로고    scopus 로고
    • Review article: Faecal markers in the assessment of activity in inflammatory bowel disease
    • Poullis A et al. (2002) Review article: faecal markers in the assessment of activity in inflammatory bowel disease. Aliment Pharmacol Ther 16: 675-681
    • (2002) Aliment. Pharmacol. Ther. , vol.16 , pp. 675-681
    • Poullis, A.1
  • 13
    • 0030663041 scopus 로고    scopus 로고
    • Functional and clinical aspects of the myelomonocyte protein calprotectin
    • Johne B et al. (1997) Functional and clinical aspects of the myelomonocyte protein calprotectin. Mol Pathol 50: 113-123
    • (1997) Mol. Pathol. , vol.50 , pp. 113-123
    • Johne, B.1
  • 14
    • 0026744132 scopus 로고
    • Assessment of the neutrophil dominating protein calprotectin in feces. A methodologic study
    • Roseth AG et al. (1992) Assessment of the neutrophil dominating protein calprotectin in feces. A methodologic study. Scand J Gastroenterol 27: 793-798
    • (1992) Scand. J. Gastroenterol. , vol.27 , pp. 793-798
    • Roseth, A.G.1
  • 15
    • 0030897788 scopus 로고    scopus 로고
    • Assessment of disease activity in ulcerative colitis by faecal calprotectin, a novel granulocyte marker protein
    • Roseth AG et al. (1997) Assessment of disease activity in ulcerative colitis by faecal calprotectin, a novel granulocyte marker protein. Digestion 58: 176-180
    • (1997) Digestion , vol.58 , pp. 176-180
    • Roseth, A.G.1
  • 16
    • 0033013167 scopus 로고    scopus 로고
    • Correlation between faecal excretion of indium-111-labelled granulocytes and calprotectin, a granulocyte marker protein, in patients with inflammatory bowel disease
    • Roseth AG et al. (1999) Correlation between faecal excretion of indium-111-labelled granulocytes and calprotectin, a granulocyte marker protein, in patients with inflammatory bowel disease. Scand J Gastroenterol 34: 50-54
    • (1999) Scand. J. Gastroenterol. , vol.34 , pp. 50-54
    • Roseth, A.G.1
  • 17
    • 0033795259 scopus 로고    scopus 로고
    • A simple method for assessing intestinal inflammation in Crohn's disease
    • Tibble J et al. (2000) A simple method for assessing intestinal inflammation in Crohn's disease. Gut 47: 506-513
    • (2000) Gut , vol.47 , pp. 506-513
    • Tibble, J.1
  • 18
    • 0003037738 scopus 로고    scopus 로고
    • Endoscopic healing after Infliximab treatment for Crohn's disease provides a longer time in relapse
    • D'Haens G et al. (2002) Endoscopic healing after Infliximab treatment for Crohn's disease provides a longer time in relapse. Gastroenterology 122 (suppl): A100
    • (2002) Gastroenterology , vol.122 , Issue.SUPPL.
    • D'Haens, G.1
  • 19
    • 6344246551 scopus 로고    scopus 로고
    • Normalization of faecal calprotectin: A predictor of mucosal healing in patients with inflammatory bowel disease
    • Roseth AG et al. (2004) Normalization of faecal calprotectin: a predictor of mucosal healing in patients with inflammatory bowel disease. Scand J Gastroenterol 39: 1017-1020
    • (2004) Scand. J. Gastroenterol. , vol.39 , pp. 1017-1020
    • Roseth, A.G.1
  • 20
    • 0034234796 scopus 로고    scopus 로고
    • Surrogate markers of intestinal inflammation are predictive of relapse in patients with inflammatory bowel disease
    • Tibble JA et al. (2000) Surrogate markers of intestinal inflammation are predictive of relapse in patients with inflammatory bowel disease. Gastroenterology 119: 15-22
    • (2000) Gastroenterology , vol.119 , pp. 15-22
    • Tibble, J.A.1
  • 21
    • 14544308315 scopus 로고    scopus 로고
    • Calprotectin is a stronger predictive markers of relapse in ulcerative colitis than in Crohn's disease
    • (in press)
    • Costa F et al. Calprotectin is a stronger predictive markers of relapse in ulcerative colitis than in Crohn's disease. Gut (in press)
    • Gut
    • Costa, F.1
  • 22
    • 0033784967 scopus 로고    scopus 로고
    • Fecal calprotectin levels predict colorectal inflammation among patients with chronic diarrhea referred for colonoscopy
    • Limburg PJ et al. (2000) Fecal calprotectin levels predict colorectal inflammation among patients with chronic diarrhea referred for colonoscopy. Am J Gastroenterol 95: 2831-2837
    • (2000) Am. J. Gastroenterol. , vol.95 , pp. 2831-2837
    • Limburg, P.J.1
  • 23
    • 0029126185 scopus 로고
    • Lactoferrin: A general review
    • Levay PF and Viljoen M (1995) Lactoferrin: a general review. Haematologica 80: 252-267
    • (1995) Haematologica , vol.80 , pp. 252-267
    • Levay, P.F.1    Viljoen, M.2
  • 24
    • 0032148122 scopus 로고    scopus 로고
    • Utility of a rapid fecal latex agglutination test detecting the neutrophil protein, lactoferrin, for diagnosing inflammatory causes of chronic diarrhea
    • Fine KD et al. (1998) Utility of a rapid fecal latex agglutination test detecting the neutrophil protein, lactoferrin, for diagnosing inflammatory causes of chronic diarrhea. Am J Gastroenterol 93: 1300-1305
    • (1998) Am. J. Gastroenterol. , vol.93 , pp. 1300-1305
    • Fine, K.D.1
  • 25
    • 0037635274 scopus 로고    scopus 로고
    • Fecal lactoferrin is a sensitive and specific marker in identifying intestinal inflammation
    • Kane SV et al. (2003) Fecal lactoferrin is a sensitive and specific marker in identifying intestinal inflammation. Am J Gastroenterol 98: 1309-1314
    • (2003) Am. J. Gastroenterol. , vol.98 , pp. 1309-1314
    • Kane, S.V.1
  • 26
    • 1242269322 scopus 로고    scopus 로고
    • Bowel inflammation as measured by fecal calprotectin: A link between lifestyle factors and colorectal cancer risk
    • Poulis A et al. (2004) Bowel inflammation as measured by fecal calprotectin: a link between lifestyle factors and colorectal cancer risk. Cancer Epidemiol Biomarkers Prev. 13: 279-284
    • (2004) Cancer Epidemiol. Biomarkers Prev. , vol.13 , pp. 279-284
    • Poulis, A.1
  • 27
    • 0033064252 scopus 로고    scopus 로고
    • Review article: The potential role of nitric oxide in chronic inflammatory bowel disorders
    • Perner A and Rask-Madsen J (1999) Review article: the potential role of nitric oxide in chronic inflammatory bowel disorders. Aliment Pharmacol Ther 13: 135-144
    • (1999) Aliment. Pharmacol. Ther. , vol.13 , pp. 135-144
    • Perner, A.1    Rask-Madsen, J.2
  • 28
    • 0031035522 scopus 로고    scopus 로고
    • Nitric oxide and inflammation: The answer is blowing in the wind
    • Lundberg JO et al. (1997) Nitric oxide and inflammation: the answer is blowing in the wind. Nat Med 3: 30-31
    • (1997) Nat. Med. , vol.3 , pp. 30-31
    • Lundberg, J.O.1
  • 29
    • 0028081788 scopus 로고
    • Greatly increased luminal nitric oxide in ulcerative colitis
    • Lundberg JO et al. (1994) Greatly increased luminal nitric oxide in ulcerative colitis. Lancet 344: 1673-1674
    • (1994) Lancet , vol.344 , pp. 1673-1674
    • Lundberg, J.O.1
  • 30
    • 0031885723 scopus 로고    scopus 로고
    • Increased luminal nitric oxide in inflammatory bowel disease as shown with a novel minimally invasive method
    • Herulf M et al. (1998) Increased luminal nitric oxide in inflammatory bowel disease as shown with a novel minimally invasive method. Scand J Gastroenterol 33: 164-169
    • (1998) Scand. J. Gastroenterol. , vol.33 , pp. 164-169
    • Herulf, M.1
  • 32
    • 0036084864 scopus 로고    scopus 로고
    • Nitric oxide production in rectal dialysate is a marker of disease activity and location in children with inflammatory bowel disease
    • Canani RB et al. (2002) Nitric oxide production in rectal dialysate is a marker of disease activity and location in children with inflammatory bowel disease. Am J Gastroenterol 97: 1574-1576
    • (2002) Am. J. Gastroenterol. , vol.97 , pp. 1574-1576
    • Canani, R.B.1
  • 33
    • 0036157878 scopus 로고    scopus 로고
    • Colonic production of nitric oxide gas in ulcerative colitis, collagenous colitis and uninflamed bowel
    • Perner A et al. (2002) Colonic production of nitric oxide gas in ulcerative colitis, collagenous colitis and uninflamed bowel. Scand J Gastroenterol 37: 183-188
    • (2002) Scand. J. Gastroenterol. , vol.37 , pp. 183-188
    • Perner, A.1
  • 34
    • 0036239353 scopus 로고    scopus 로고
    • Increased rectal nitric oxide in children with active inflammatory bowel disease
    • Ljung T et al. (2002) Increased rectal nitric oxide in children with active inflammatory bowel disease. J Pediatr Gastroenterol Nutr 34: 302-306
    • (2002) J. Pediatr. Gastroenterol. Nutr. , vol.34 , pp. 302-306
    • Ljung, T.1
  • 35
    • 0034875748 scopus 로고    scopus 로고
    • Rectal nitric oxide assessment in children with Crohn disease and ulcerative colitis. Indicator of ileocaecal and colorectal affection
    • Ljung T et al. (2001) Rectal nitric oxide assessment in children with Crohn disease and ulcerative colitis. Indicator of ileocaecal and colorectal affection. Scand J Gastroenterol 36: 1073-1076
    • (2001) Scand. J. Gastroenterol. , vol.36 , pp. 1073-1076
    • Ljung, T.1
  • 36
    • 0033503027 scopus 로고    scopus 로고
    • Increased nitric oxide in infective gastroenteritis
    • Herulf M et al. (1999) Increased nitric oxide in infective gastroenteritis. J Infect Dis 108: 542-545
    • (1999) J. Infect. Dis. , vol.108 , pp. 542-545
    • Herulf, M.1
  • 37
    • 9844253884 scopus 로고    scopus 로고
    • Increased nitric oxide production in collagenous and lymphocytic colitis
    • Lundberg JO et al. (1997) Increased nitric oxide production in collagenous and lymphocytic colitis. Eur J Clin Invest 27: 869-871
    • (1997) Eur. J. Clin. Invest. , vol.27 , pp. 869-871
    • Lundberg, J.O.1
  • 38
    • 0037261281 scopus 로고    scopus 로고
    • Luminal nitric oxide and epithelial expression of inducible and endothelial nitric oxide synthase in collagenous and lymphocytic colitis
    • Olesen M et al. (2003) Luminal nitric oxide and epithelial expression of inducible and endothelial nitric oxide synthase in collagenous and lymphocytic colitis. Scand J Gastroenterol 38: 66-72
    • (2003) Scand. J. Gastroenterol. , vol.38 , pp. 66-72
    • Olesen, M.1
  • 39
    • 1642276194 scopus 로고    scopus 로고
    • Rectal nitric oxide gas and stool cytokine levels during the course of infectious gastroenteritis
    • Enocksson A et al. (2004) Rectal nitric oxide gas and stool cytokine levels during the course of infectious gastroenteritis. Clin Diagn Lab Immunol 11: 250-254
    • (2004) Clin. Diagn. Lab. Immunol. , vol.11 , pp. 250-254
    • Enocksson, A.1
  • 40
    • 0037384348 scopus 로고    scopus 로고
    • Exhaled NO and plasma cGMP increase after endotoxin infusion in healthy volunteers
    • Soop A et al. (2003) Exhaled NO and plasma cGMP increase after endotoxin infusion in healthy volunteers. Eur Respir J 21: 594-599
    • (2003) Eur. Respir. J. , vol.21 , pp. 594-599
    • Soop, A.1
  • 41
    • 0029816226 scopus 로고    scopus 로고
    • Expression of inducible nitric oxide synthase and nitrotyrosine in colonic epithelium in inflammatory bowel disease
    • Singer II et al. (1996) Expression of inducible nitric oxide synthase and nitrotyrosine in colonic epithelium in inflammatory bowel disease. Gastroenterology 111: 871-885
    • (1996) Gastroenterology , vol.111 , pp. 871-885
    • Singer, I.I.1
  • 42
    • 0034715965 scopus 로고    scopus 로고
    • Calprotectin, a faecal marker of organic gastrointestinal abnormality
    • Fagerhol MK (2000) Calprotectin, a faecal marker of organic gastrointestinal abnormality. Lancet 356: 1783-1784
    • (2000) Lancet , vol.356 , pp. 1783-1784
    • Fagerhol, M.K.1
  • 43
    • 0035109696 scopus 로고    scopus 로고
    • Management of the irritable bowel syndrome
    • Camilleri M (2001) Management of the irritable bowel syndrome. Gastroenterology 120: 652-668
    • (2001) Gastroenterology , vol.120 , pp. 652-668
    • Camilleri, M.1
  • 44
    • 0036320081 scopus 로고    scopus 로고
    • Use of surrogate markers of inflammation and Rome criteria to distinguish organic from nonorganic intestinal disease
    • Tibble JA et al. (2002) Use of surrogate markers of inflammation and Rome criteria to distinguish organic from nonorganic intestinal disease. Gastroenterology 123: 450-460
    • (2002) Gastroenterology , vol.123 , pp. 450-460
    • Tibble, J.A.1
  • 45
    • 1242272866 scopus 로고    scopus 로고
    • Microscopic colitis: A common diarrhoeal disease An epidemiological study in Orebro, Sweden, 1993-1998
    • Olesen M et al. (2004) Microscopic colitis: a common diarrhoeal disease. An epidemiological study in Orebro, Sweden, 1993-1998. Gut 53: 346-350
    • (2004) Gut , vol.53 , pp. 346-350
    • Olesen, M.1
  • 46
    • 9944246056 scopus 로고    scopus 로고
    • Microscopic colitis: A missed diagnosis?
    • Nielsen OH et al. (2004) Microscopic colitis: a missed diagnosis? Lancet 364: 2055-2057
    • (2004) Lancet , vol.364 , pp. 2055-2057
    • Nielsen, O.H.1
  • 47
    • 0034906225 scopus 로고    scopus 로고
    • Fecal calprotectin: Validation as a nonivasive measure of bowel inflammation in childhood inflammatory bowel disease
    • Bunn SK et al. (2001) Fecal calprotectin: validation as a nonivasive measure of bowel inflammation in childhood inflammatory bowel disease. J Pediatr Gastroenterol Nutr 33: 14-22
    • (2001) J. Pediatr. Gastroenterol. Nutr. , vol.33 , pp. 14-22
    • Bunn, S.K.1
  • 48
    • 1542540223 scopus 로고    scopus 로고
    • Fecal calprotectin levels in healthy children studied with an improved assay
    • Fagerberg UL et al. (2003) Fecal calprotectin levels in healthy children studied with an improved assay. J Pediatr Gastroenterol Nutr 37: 468-472
    • (2003) J. Pediatr. Gastroenterol. Nutr. , vol.37 , pp. 468-472
    • Fagerberg, U.L.1
  • 49
    • 0036174707 scopus 로고    scopus 로고
    • Faecal calprotectin levels in infants with infantile colic, healthy infants, children with inflammatory bowel disease, children with recurrent abdominal pain and healthy children
    • Olafsdottir E et al. (2002) Faecal calprotectin levels in infants with infantile colic, healthy infants, children with inflammatory bowel disease, children with recurrent abdominal pain and healthy children. Acta Paediatr 91: 45-50
    • (2002) Acta Paediatr. , vol.91 , pp. 45-50
    • Olafsdottir, E.1
  • 50
    • 20344386605 scopus 로고    scopus 로고
    • Birth-related changes in intracolonic nitric oxide and hydrogen gas
    • (in press)
    • Sobko T et al. Birth-related changes in intracolonic nitric oxide and hydrogen gas. Allergy (in press)
    • Allergy
    • Sobko, T.1
  • 51
    • 4544340873 scopus 로고    scopus 로고
    • Activity of inducile and neuronal nitric oxide synthases in colonic mucosa predicts progression of ulcerative colitis
    • Menchen L et al. (2004) Activity of inducile and neuronal nitric oxide synthases in colonic mucosa predicts progression of ulcerative colitis. Am J Gastroenterol 99: 1756-1764
    • (2004) Am. J. Gastroenterol. , vol.99 , pp. 1756-1764
    • Menchen, L.1
  • 52
    • 0034117388 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase activity is expressesd not only in inflamed but also in normal colonic mucosa in patients with ulcerative colitis: A potential prognostic marker
    • Colon AL et al. (2000) Inducible nitric oxide synthase activity is expressesd not only in inflamed but also in normal colonic mucosa in patients with ulcerative colitis: a potential prognostic marker. Am J Gastroenterol 95: 1371-1373
    • (2000) Am. J. Gastroenterol. , vol.95 , pp. 1371-1373
    • Colon, A.L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.