Synthesis and 5-HT1A/5-HT2A activity of some butyl analogs in the group of phenylpiperazine alkyl pyrimido[2,1-f]theophyllines

Pharmacological Reports

Volumn 57, Issue 2, 2005, Pages 229-235

  Kołaczkowski, Marcin ^a   Zajdel, Paweł ^a   Fhid, Omeran ^a   Duszyńska, Beata ^b   Tatarczyńska, Ewa ^b   Pawłowski, Maciej ^a  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^b INSTITUTE OF PHARMACOLOGY   (Poland)

Author keywords

1 phenylpiperazines; 5 HT1A ligands; 5 HT1A receptor functional activity; Pyrimido 2,1 f theophyllines

Indexed keywords

1 PHENYLPIPERAZINE DERIVATIVE; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 9H PYRIMIDIN 8 ON[2,1 F]THEOPHYLLINE; ALKYL GROUP; CARBENE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; SEROTONIN 1A RECEPTOR; SEROTONIN 2A RECEPTOR; THEOPHYLLINE DERIVATIVE; UNCLASSIFIED DRUG; DRUG DERIVATIVE; LIGAND; PIPERAZINE DERIVATIVE; SEROTONIN RECEPTOR AFFECTING AGENT; THEOPHYLLINE;

AGONIST; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; IN VIVO STUDY; MALE; NONHUMAN; PRESYNAPTIC NERVE; PROTEIN FUNCTION; PROTEIN SYNTHESIS; RAT; ANIMAL; ANIMAL BEHAVIOR; BINDING COMPETITION; BODY TEMPERATURE; BRAIN CORTEX; CHEMISTRY; DRUG EFFECT; HIPPOCAMPUS; METABOLISM; MOUSE; RADIOASSAY; STRUCTURE ACTIVITY RELATION; SYNTHESIS; WISTAR RAT;

ANIMALS; BEHAVIOR, ANIMAL; BINDING, COMPETITIVE; BODY TEMPERATURE; CEREBRAL CORTEX; HIPPOCAMPUS; LIGANDS; MALE; MICE; PIPERAZINES; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTOR, SEROTONIN, 5-HT1A; RECEPTOR, SEROTONIN, 5-HT2A; SEROTONIN AGENTS; STRUCTURE-ACTIVITY RELATIONSHIP; THEOPHYLLINE;

EID: 20344371919     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: None     Document Type: Article

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