Variations within OLF1/EBF-associated zinc finger protein gene confer susceptibility to lupus nephritis in Chinese population

National Medical Journal of China

Volumn 85, Issue 14, 2005, Pages 949-954

  Liang, Dong ^a   Huang, Xiu Qin ^b   Shen, Nan ^b   Mao, Han Qian ^b   Feng, Xue Bing ^b   Huang, Xin Fang ^b   Tang, Jian Ping ^b   Chen, Xiao Xiang ^b   Chen, Shun Le ^b   Gu, Yue Ying ^b   Bao, Chun De ^b   Wang, Yuan ^b   Qian, Jie ^b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b NONE

Author keywords

Lupus erythematosus, systemic; Lupus nephritis; OAZ gene

Indexed keywords

ALANINE; CYSTEINE; GLYCINE; PROTEIN EBF; PROTEIN OLF1; THREONINE; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ALLELE; ARTICLE; CHINA; CHINESE; COMPUTER PROGRAM; CONTROLLED STUDY; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HETEROZYGOSITY; HUMAN; INFORMATION PROCESSING; LUPUS ERYTHEMATOSUS NEPHRITIS; MAJOR CLINICAL STUDY; MICROSATELLITE MARKER; PATHOGENESIS; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL SIGNIFICANCE;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; DNA-BINDING PROTEINS; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LINKAGE DISEQUILIBRIUM; LUPUS NEPHRITIS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; ZINC FINGERS;

EID: 20244385591     PISSN: 03762491     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Gaffney PM , Ortmann WA , Selby SA , et al. Genome screening in human systemic lupus erythematosus: results from a second Minnesota cohort and combined analyses of 187 sib-pair families. Am J Hum Genet, 2000, 66: 547-556.
2. Gaffney PM , Kearns GM , Shark KB, et al. A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families. Proc Natl Acad Sci USA , 1998, 95: 14875-14879.
3. Shai R, Quismorio FP Jr, Li L, et al. Genome-wide screen for systemic lupus erythematosus susceptibility genes in multiplex families. Hum Mol Genet, 1999, 8: 639-644.
4. Feng XB, Shen N, Chen SL, et al. Susceptibility gene of systemic lupus erythematosus in 16q12 in Chinese cohort. Chin J Med Genet, 2003, 20: 27-30.
5. Wrana JL. Regulation of smad activity. Cell, 2000, 100: 1892.
6. Tsai RY, Reed RR. Cloning and functional characterization of ROAZ, a zinc finger protein that interacts with O/E-1 to regulate gene expression: implications for olfactory neuronal development. J Neurosci, 1997, 17: 4159-4169.
7. van Laere AS, Nguyen M, Braunschweig M, et al. A regulatory mutation in IGF2 causes a major QTL effect on muscle growth in the pig. Nature,2003, 425: 832-836.
8. Tokuhiro S, Yamada R, Chang X, et al. An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis. Nat Genet, 2003, 35: 341-348.
9. Cawley S, Bekiranov S, Ng HH, et al. Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs. Cell, 2004, 116: 499-509.
10. Grande JP. Mechanisms of progression of renal damage in lupus nephritis: pathogenesis of renal scarring. Lupus, 1998, 7: 604-610.