Inactivation of the Na-Cl Co-transporter (NCC) gene is associated with high BMD through both renal and bone mechanisms: Analysis of patients with Gitelman syndrome and Ncc null mice

Journal of Bone and Mineral Research

Volumn 20, Issue 5, 2005, Pages 799-808

  Nicolet Barousse, Laurence ^a   Blanchard, Anne ^a,f   Roux, Christian ^b   Pietri, Laurence ^c   Bloch Faure, May ^c   Kolta, Sami ^b   Chappard, Christine ^a   Geoffroy, Valérie ^d   Morieux, Caroline ^d   Jeunemaitre, Xavier ^a   Shull, Gary E ^e   Meneton, Pierre ^c   Paillard, Michel ^a   Houillier, Pascal ^a   De Vernejoul, Marie Christine ^d  

^a HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^b Hôpital Cochin ^*  (France)

^c INSERM   (France)

^d HÔPITAL LARIBOISIÈRE   (France)

^e UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^f College of Medicine ^*  (France)

Author keywords

BMD; Bone remodeling; Inborn error; Magnesium depletion; Mice; Renal tubular transport; Transgenic

Indexed keywords

CALCIUM ION; COTRANSPORTER; GENE PRODUCT; MAGNESIUM ION; PARATHYROID HORMONE; SODIUM CHLORIDE COTRANSPORTER; THIAZIDE DIURETIC AGENT; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE DENSITY; BONE REMODELING; CALCIUM EXCRETION; CALCIUM INTAKE; CALCIUM METABOLISM; CLINICAL ARTICLE; CONTROLLED STUDY; CORTICAL BONE; FEMALE; FEMUR; GENE MUTATION; GITELMAN SYNDROME; GLOMERULUS FILTRATION RATE; HUMAN; HUMAN CELL; HYPOPARATHYROIDISM; KIDNEY TUBULE ABSORPTION; KNOCKOUT MOUSE; LUMBAR SPINE; MALE; MORPHOMETRICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; NULL ALLELE; OSTEOCLAST; PARATHYROID HORMONE BLOOD LEVEL; TRABECULAR BONE;

ADOLESCENT; ADULT; AGE FACTORS; AGED; ANIMALS; BENZOTHIADIAZINES; BODY WEIGHT; BONE AND BONES; BONE DENSITY; CALCIUM; CASE-CONTROL STUDIES; DIURETICS; FEMALE; HUMANS; HYPOPARATHYROIDISM; KIDNEY; KIDNEY DISEASES; MAGNESIUM; MALE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MIDDLE AGED; MUTATION; PHENOTYPE; SODIUM CHLORIDE; SODIUM CHLORIDE SYMPORTER INHIBITORS; SODIUM CHLORIDE SYMPORTERS; SYMPORTERS; SYNDROME; THIADIAZINES; TIBIA; TIME FACTORS; TRANSGENES;

EID: 20244371697     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/JBMR.041238     Document Type: Article

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