Telomerase activity in thyroid neoplasms evaluated by the expression of human telomerase reverse transcriptase (hTERT)

Anticancer Research

Volumn 25, Issue 1 B, 2005, Pages 509-514

  Ito, Yasuhiro ^a   Yoshida, Hiroshi ^a   Tomoda, Chisato ^a   Uruno, Takashi ^a   Takamura, Yuuki ^a   Miya, Akihiro ^a   Kobayashi, Kaoru ^a   Matsuzuka, Fumio ^a   Kuma, Kanji ^a   Miyauchi, Akira ^a  

^a KUMA HOSPITAL   (Japan)

Author keywords

Follicular tumor; hTERT; Immunohistochemistry

Indexed keywords

MONOCLONAL ANTIBODY; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE;

ADULT; AGED; ANAPLASTIC CARCINOMA; ARTICLE; ASPIRATION BIOPSY; CANCER STAGING; DIAGNOSTIC VALUE; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MALIGNANT TRANSFORMATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; TELOMERIC REPEAT AMPLIFICATION PROTOCOL; THYROID FOLLICLE CELL; THYROID TUMOR; TUMOR GROWTH;

ADENOCARCINOMA, FOLLICULAR; ADENOMA; BIOPSY, FINE-NEEDLE; CARCINOMA, PAPILLARY; CELL DIFFERENTIATION; DNA-BINDING PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHATIC METASTASIS; RNA, MESSENGER; SENSITIVITY AND SPECIFICITY; TELOMERASE; THYROID NEOPLASMS;

EID: 20144387428     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. LiVolsi VA and Asa SL: The demise of follicular carcinoma of the thyroid gland. Thyroid 4: 233-237, 1994.
2. Fagin JA: Molecular genetics of tumors of thyroid follicular cells. In: The Thyroid 8th ed. Lippincott Williams & Wilkins, 2001, 886-898.
3. Aldinger KA, Samaan NA, Ibanez M and Hill CS Jr: Anaplastic carcinoma of the thyroid: a review of 84 cases of spindle and giant-cell carcinoma of the thyroid. Cancer 41: 2267-2275, 1978.
4. Ito T, Seyama T and Mizuno T: Unique association of p53 mutations with undifferentiated but not with differentiated carcinomas of the thyroid gland. Cancer Res 52: 1369-1371, 1992.
5. Shay JW, Gazdar AF and Wright WE: You haven't heard the end of it: telomere loss may link human aging with cancer. Canadian J Aging 14: 511-524, 1995.
6. Rhyu MS: Telomeres, telomerase, and immortality. J Natl Cancer Inst 87: 884-894, 1995.
7. Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, Ho PL, Coviello GM, Wright WE, Weinrich SL and Shay JW: Specific association of human telomerase activity with immortal cells and cancer. Science 266: 2011-2015, 1994.
8. Hiyama E, Gallahon L, Kataoka T, Kuroi K, Yokoyama T, Gazdar AF, Hiyama K Piatyszek MNA and Shay JW: Telomerase activity in human breast tumors. J Natl Cancer Inst 88: 116-122, 1996.
9. Sugino T, Yoshida K, Bolodeoku J, Tahara H, Buley I, Manek S, Wells C, Goodison S, Ide T, Suzuki T, Tahara E and Train D: Telomerase activity in human breast cancer and benign breast lesions: diagnostic applications in clinical specimens, including fine needle aspirates. Int J Cancer 69: 301-306, 1996.
10. Bednarek AK, Sahin A, Brenner AJ, Johnston DA and Aldaz CM: Analysis of telomerase activity levels in breast cancer: positive detection at the in situ breast carcinioma stage. Clin Cancer Res. 3: 11-16, 1997.
11. Tahara H, Yasui W, Tahara E, Fujimoto J, Ito K, Tamai K, Nakayama J, Ishikawa F, Tahara E and Ide T: Immunohistochemical detection of human telomerase catalytic component, hTERT, in human colorectal tumor and non-tumor tissue sections. Oncogene 18: 1561-1567, 1999.
12. Counter CM, Hirte HW, Bacchetti S and Harley CB: Telomerase activity in human ovarian carcinoma. Proc Natl Acad Sci USA 91: 2900-2904, 1994.
13. Brousset P, Chaouche N, Leprat F, Branet-Brousset F, Trouette H, Zenou RC, Merlio JP and Delsol G: Telomerase activity in human thyroid carcinomas originating from the follicular cells. J Clin Endocrinol Metab 82: 4214-4216, 1997.
14. Okayasu I, Osakabe T, Fujiwara M, Fukuda H, Kalo M and Oshimura M: Significant correlation of telomerase activity in thyroid papillary carcinomas with cell differentiation, proliferation and extrathyroidal extension. Jpn J Cancer Res 88: 965-970, 1997.
15. Umbricht CB, Saji M, Westra WH, Udelsman R, Zeiger MA and Sukumar S: Telomerase activity: a marker to distinguish follicular thyroid adenoma from carcinoma. Cancer Res 57: 2144-2147, 1997.
16. Haugen BR, Nawaz S, Markham N, Hashizumi T, Shroyer AL, Werness B and Shoroyer KR: Telomerase activity in benign and malignant thyroid tumors. Thyroid 7: 337-342, 1997.
17. Aogi K, Kitahara K, Buley I, Backdahl M, Tahara H, Sugino T, Tarin D and Goodison S: Telomerase activity in lesions of the thyroid: application to diagnosis of clinical samples including fine-needle aspirates. Clin Cancer Res 4: 1965-1970, 1998.
18. Aogi K, Kitahara K, Urquidi V, Tarin D and Goodison S: Comparison of telomerase and CD44 expression as diagnostic tumor markers in lesions of the thyroid. Clin Cancer Res 5: 2790-2797, 1999.
19. Cheng AJ, Lin JD and Wang TCV: Telomerase activity in benign and malignant human thyroid tissues. Br J Cancer 77: 2177-2180, 1998.
20. Kammori M, Takubo K, Nakamura K, Furugouri E, Endo H, Kanauchi H, Mimura Y and Kaminishi M: Telomerase activity and telomere length in benign and malignant human thyroid tissues. Cancer Lett 159: 175-181, 2000.
21. Saji M, Westra WH, Chen H, Umbricht CB, Tuttle M, Box MF, Udelsman R, Sukumar S and Zeiger M: Telomerase activity in the differential diagnosis of papillary carcinoma of the thyroid. Surgery 122: 1137-1140, 1997.
22. Kilian A, Bowtell DD, abud HE, Hime GR, Venter DJ, Keese PK, Duncan EL, Reddel RR and Jefferson RA: Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types. Hum Mol Genet 6: 2011-2019, 1997.
23. Takakura M, Kyo S, Kanaya T, Tanaka M and Inoue M: Expression of human telomerase subunits and correlation with telomerase activity in cervical cancer. Cancer Res 58: 1558-1561, 1998.
24. Autexier C, Pruzan R, Funk WD and Greider CW: Reconstitution of human telomerase activity and identification of a minimal functional region of the human telomerase RNA. EMBO J 15: 5928-5932, 1996.
25. Saji M, Xydas S, Westra WH, Liang CK, Clark DP, Udelsman R, Umbricht CB, Sukumar S and Zeiger MA: Human telomerase reverse transcriptase (hTERT) gene expression in thyroid neoplasms. Clin Cancer Res 5: 1483-1489, 1999.
26. Zeiger MA, Smallridge RC, Clark DP, Liang CK, Carty SE, Watson CG, Udelsman R and Saji M: Human telomerase reverse transcriptase (hTERT) gene expression in FNA samples from thyroid neoplasms. Surgery 126: 1195-1199, 1999.
27. Chou SJ, Chen CM, Harn HJ, Chen CJ and Liu YC: In situ detection of hTERT mRNA relates to Ki-67 labeling index in papillary thyroid carcinoma. J Surg Res 99: 75-83, 2001.
28. Hiyama K, Hirai Y, Koizumi S, Akiyama M, Hiyama E, Piatyszek MA, Shay JW, Ishioka S and Yamakido M: Activation of telomerase in human lymphocytes and hematopoietic progenitor cells. J Immunol 155: 3711-3715, 1995.
29. Liu K, Schoonmaker MM, Levine BL, June CH, Hodes RJ and Weng NP: Constitutive and regulated expression of telomerase reverse transcriptase (hTERT) in human lymphocytes. Proc Natl Acad Sci USA 96: 5147-5152, 1999.