Arginase-1 overexpression induces cationic amino acid transporter-1 in psoriasis

Free Radical Biology and Medicine

Volumn 38, Issue 8, 2005, Pages 1073-1079

  Schnorr, Oliver ^a   Schuier, Maximilian ^a   Kagemann, Guido ^a   Wolf, Ronald ^a   Walz, Markus ^a   Ruzicka, Thomas ^a   Mayatepek, Ertan ^a   Laryea, Maurice ^a   Suschek, Christoph V ^a   Kolb Bachofen, Victoria ^a   Sies, Helmut ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Arginase; Cationic amino acid transporter; Free radicals; L Arginine; Nitric oxide; Psoriasis

Indexed keywords

AMINO ACID TRANSPORTER; ARGINASE; ARGININE; INDUCIBLE NITRIC OXIDE SYNTHASE; ISOPROTEIN; MESSENGER RNA; NITRIC OXIDE; ORNITHINE;

ADULT; ARTICLE; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE SEQUENCE; GENETIC TRANSFECTION; HUMAN; HUMAN TISSUE; KERATINOCYTE; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PSORIASIS; REGULATORY MECHANISM; UPREGULATION;

EID: 20144364614     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2005.01.005     Document Type: Article

References (17)

1. V. Kolb-Bachofen, and D. Bruch-Gerharz Langerhans cells, nitric oxide, keratinocytes and psoriasis Immunol. Today 20 1999 289
2. D. Bruch-Gerharz, T. Ruzicka, and V. Kolb-Bachofen Nitric oxide in human skin: current status and future prospects J. Invest. Dermatol. 110 1998 1 7
3. D. Bruch-Gerharz, O. Schnorr, C. Suschek, K.F. Beck, J. Pfeilschifter, T. Ruzicka, and V. Kolb-Bachofen Arginase 1 overexpression in psoriasis- limitation of inducible nitric oxide synthase activity as a molecular mechanism for keratinocyte hyperproliferation Am. J. Pathol. 162 2003 203 211
4. N. Zimmermann, N.E. King, J. Laporte, M. Yang, A. Mishra, S.M. Pope, E.E. Muntel, D.P. Witte, A.A. Pegg, P.S. Foster, Q. Hamid, and M.E. Rothenberg Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis J. Clin. Invest. 111 2003 1863 1874
5. R. Deves, and C.A. Boyd Transporters for cationic amino acids in animal cells: discovery, structure, and function Physiol. Rev. 78 1998 487 545
6. N. Vekony, S. Wolf, J.P. Boissel, K. Gnauert, and E.I. Closs Human cationic amino acid transporter hCAT-3 is preferentially expressed in peripheral tissues Biochemistry 40 2001 12387 12394
7. F. Verrey, E.I. Closs, C.A. Wagner, M. Palacin, H. Endou, and Y. Kanai CATs and HATs: the SLC7 family of amino acid transporters Pflugers Arch. 447 2004 532 542
8. K. Kawahara, T. Gotoh, S. Oyadomari, M. Kajizono, A. Kuniyasu, K. Ohsawa, Y. Imai, S. Kohsaka, H. Nakayama, and M. Mori Co-induction of argininosuccinate synthetase, cationic amino acid transporter-2, and nitric oxide synthase in activated murine microglial cells Brain Res. Mol. Brain Res. 90 2001 165 173
9. A. Habermeier, S. Wolf, U. Martine, P. Graf, and E.I. Closs Two amino acid residues determine the low substrate affinity of human cationic amino acid transporter-2A J. Biol. Chem. 278 2003 19492 19499
10. V. Krischel, D. Bruch-Gerharz, C. Suschek, K.D. Kroncke, T. Ruzicka, and V. Kolb-Bachofen Biphasic effect of exogenous nitric oxide on proliferation and differentiation in skin derived keratinocytes but not fibroblasts J. Invest. Dermatol. 111 1998 286 291
11. H. Li, C.J. Meininger, K.A. Kelly, J.R. Hawker Jr., S.M. Morris Jr., and G. Wu Activities of arginase I and II are limiting for endothelial cell proliferation Am. J. Physiol. Regul. Integr. Comp. Physiol. 282 2002 R64 R69
12. G.B.E. Jemec, and H.C. Wulf The applicability of clinical scoring systems: SCORAD and PASI in psoriasis and atopic dermatitis Acta Derm.Venereol. 77 1997 392 393
13. K.S. Aulak, R. Mishra, L.Y. Zhou, S.L. Hyatt, W. de Jonge, W. Lamers, M. Snider, and M. Hatzoglou Post-transcriptional regulation of the arginine transporter Cat-1 by amino acid availability J. Biol. Chem. 274 1999 30424 30432
14. O. Schnorr, C.V. Suschek, and V. Kolb-Bachofen The importance of cationic amino acid transporter expression in human skin J. Invest. Dermatol. 120 2003 1016 1022
15. E.I. Closs, P. Graf, A. Habermeier, J.M. Cunningham, and U. Forstermann Human cationic amino acid transporters hCAT-1, hCAT-2A, and hCAT-2B: three related carriers with distinct transport properties Biochemistry 36 1997 6462 6468
16. C.R. Morris, M. Poljakovic, S.M. Morris, and M.T. Gladwin Decreased L-arginine bioavailability and elevated arginase activity in sickle cell disease: a novel pathway towards pulmonary hypertension? Blood 102 2003 763A 764A
17. C.R. Morris, S.M. Morris Jr., W. Hagar, J. Van Warmerdam, S. Claster, D. Kepka-Lenhart, L. Machado, F.A. Kuypers, and E.P. Vichinsky Arginine therapy: a new treatment for pulmonary hypertension in sickle cell disease? Am. J. Respir. Crit. Care. Med. 168 1 2003 63 69