Effects of protein-bound polysaccharide isolated from pumpkin on insulin in diabetic rats

Plant Foods for Human Nutrition

Volumn 60, Issue 1, 2005, Pages 13-16

  Quanhong, Li ^a   Caili, Fu ^a   Yukui, Rui ^a   Guanghui, Hu ^a   Tongyi, Cai ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

Author keywords

Activity guided isolation; Hypoglycemic activity; Insulin; Protein bound polysaccharide; Pumpkin

Indexed keywords

ANTIDIABETIC AGENT; INSULIN; POLYSACCHARIDE;

ANIMAL; ARTICLE; CHEMISTRY; DOSE RESPONSE; EXPERIMENTAL DIABETES MELLITUS; MALE; METABOLISM; PHYTOTHERAPY; PROTEIN BINDING; RANDOMIZATION; RAT; SPRAGUE DAWLEY RAT; SQUASH;

ANIMALS; CUCURBITA; DIABETES MELLITUS, EXPERIMENTAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPOGLYCEMIC AGENTS; INSULIN; MALE; PHYTOTHERAPY; POLYSACCHARIDES; PROTEIN BINDING; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 20144363468     PISSN: 09219668     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11130-005-2536-x     Document Type: Article

References (18)

1. Zhang F, Sun D, Li M (1995) Preparation of Astraglus polysaccharide and its therapeutic effect on hepatitis. J Chin Pharm Biotechnol 2: 26-28.
2. Tian G, Feng Y (1995) Evolution of study on plant polysaccharide. J Chin Tradit Med 20: 441-445.
3. Wang Q, Hong H, Zhao Z, Shen Y, Cheng G (2002) Effect of polysaccharides-2b from Mudan cortex on type 2 diabetes mellitus rats and its mechanism. Chin Pharmacol Bull 18: 456-459.
4. Konno C, Sugiyama K, Kano M (1984) Isolation and hypoglycaemic activity of panaxans A, B, C, D, and E, glycans of Panax ginseng roots. Planta Med 50: 434-436.
5. Xu Z, Zhou S, Huang L (2000) Protective effect of Coixan on pancreatic islet β cell injury by Alloxan in rats. Chin Pharmacol Bull 16: 639-642.
6. Jiangsu New Medical College (1985) Dictionary of Chinese Traditional and Herbal Drugs. Shanghai Science and Technology Publishing Company of China.
7. Zhang Y, Yao H (2002) Study on effect of hypoglycemia of different type pumpkin. J Chin Food Sci 23: 118-120.
8. Chen Z, Wang X, Jie Y, Huang C, Zhang G (1994) Study on hypoglycemia and hypotension function of pumpkin powder on human. Jiangxi Chin Med 25: 50.
9. Xiong X, Cao J (2001) Study of extraction and isolation of effective pumpkin polysaccharide component and its reducing glycemia function. China J MAP 18: 662-664.
10. Szkudelski T (2001) The mechanism of alloxan and streptozotocin action in β cells of the rat pancreas. Physiol Res 50: 536-546.
11. Zhang W (1987) Biochemistry about complex polysaccharides. Shanghai Science and Technology Publishing Company of China.
12. Dubois M, Gilles KA, Hamilton JK, Rebers PA, Smith F (1956) Colorimetric method for determination of carbohydrates andrelated substances. Anal Chem 28: 350-356.
13. Kim SH, Kim HW, Choi EC, Kim BK (1993) Immunological studies on Collybia confluens. J Korean Cancer Assoc 25: 288-298.
14. Seong-Kug Eo, Young-So Kim, Chong-Kil Lee, Seong-Sun Han (1999) Antiherpetic activities of various protein-bound polysaccharides isolated from Ganoderma lucidum. J Ethnopharmacol 68: 175-181.
15. Sone Y, Okuda R, Wada N, Kishida E, Misaki A (1985) Structures and antitumor activities of the polysaccharides isolated from fruiting body and the growing culture of mycelium of Ganoderma lucidum. Agric Biol Chem 49: 2541-2653.
16. Reaven GM (1988) Role of insulin resistance in human disease. Diabetes 37: 1597-1607.
17. Grandy SF, Buse MG, Crouch RK (1982) Protective role of superoxide dismutase against diabetogenic drugs. J Clin Invest 70: 650-658.
18. Yadav S, Vats V, Dhunnoo Y, Grover JK (2002) Hypoglycemic and antihyperglycemic activity of Murraya koenigii leaves in diabetic rats. J Ethnopharmacol 82: 111-116.