Identification of human T cell epitopes in Japanese cypress pollen allergen, Cha o 1, elucidates the intrinsic mechanism of cross-allergenicity between Cha o 1 and Cry j 1, the major allergen of Japanese cedar pollen, at the T cell level

Clinical and Experimental Allergy

Volumn 35, Issue 5, 2005, Pages 664-671

  Sone, T ^a   Dairiki, K ^b   Morikubo, K ^b   Shimizu, K ^b   Tsunoo, H ^b   Mori, T ^b   Kino, Kohsuke ^b  

^a SAITAMA MEDICAL UNIVERSITY   (Japan)

^b MEIJI DAIRIES CORPORATION   (Japan)

Author keywords

Allergen; Cha o 1; Cross allergenicity; Cry j 1; Pollinosis; T cell clone; T cell epitope; T cell line

Indexed keywords

CHA O 1 ALLERGEN; CRY J 1 ALLERGEN; EPITOPE; IMMUNOGLOBULIN E; POLLEN ANTIGEN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CHAMAECYPARIS; CLINICAL ARTICLE; CONTROLLED STUDY; CROSS ALLERGY; CUPRESSACEAE; FEMALE; HUMAN; HUMAN CELL; JAPAN; JAPANESE CEDAR; LYMPHOCYTE CLONE; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; POLLEN; POLLEN ALLERGY; PRIORITY JOURNAL; RESPIRATORY TRACT ALLERGY; SEASONAL VARIATION; SENSITIZATION; T LYMPHOCYTE; TH2 CELL;

ADULT; ALLERGENS; AMINO ACID SEQUENCE; ANTIBODY SPECIFICITY; CELL LINE; CHAMAECYPARIS; CRYPTOMERIA; EPITOPES; FEMALE; HUMANS; IMMUNOGLOBULIN E; LYMPHOCYTE ACTIVATION; MALE; MIDDLE AGED; PLANT PROTEINS; POLLEN; RHINITIS, ALLERGIC, SEASONAL; T-LYMPHOCYTES; TH2 CELLS;

EID: 20044390815     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2005.02221.x     Document Type: Article

References (36)

1. Di Felice G, Barletta B, Tinghino R, Pini C. Cupressaceae pollinosis: identification, purification and cloning of relevant allergens. Int Arch Allergy Immunol 2001; 125:280-9.
2. Weber RW. Patterns of pollen cross-allergenicity. J Allergy Clin Immunol 2003; 112:229-39.
3. Schwietz LA, Goetz DW, Whisman BA, Reid MJ. Cross-reactivity among conifer pollens. Ann Allergy Asthma Immunol 2000; 84: 87-93.
4. Yasueda H, Yui Y, Shimizu T, Shida T. Isolation and partial characterization of the major allergen from Japanese cedar (Cryptomeria japonica) pollen. J Allergy Clin Immunol 1983; 71:77-86.
5. Namba H, Saitou K, Sahashi N et al. Relationship between pollen counts of Cryptomeria japonica and Cupressaceae and the severity of allergic symptoms. Allergol Int 2001; 50:133-42.
6. Ito H, Nishimura J, Suzuki M et al. Specific IgE to Japanese cypress (Chamaecyparis obtusa) in patients with nasal allergy. Ann Allergy Asthma Immunol 1995; 74:299-303.
7. Ito H, Suzuki M, Mamiya S et al. Analysis of the allergenic components of Hinoki cypress (Chamaecyparis obtusa) pollen by immunoblotting with the sera from patients with Japanese cedar pollinosis. Allergol Int 1996; 45:181-6.
8. Sone T, Komiyama N, Shimizu K, Kusakabe T, Morikubo K, Kino K. Cloning and sequencing of cDNA coding for Cry j I, a major allergen of Japanese cedar pollen. Biochem Biophys Res Commun 1994; 199:619-25.
9. Komiyama N, Sone T, Shimizu K, Morikubo K, Kino K. cDNA cloning and expression of Cry j II, the second major allergen of Japanese cedar pollen. Biochem Biophys Res Commun 1994; 201:1021-8.
10. Namba M, Kurose M, Torigoe K et al. Molecular cloning of the second major allergen, Cry j II, from Japanese cedar pollen. FEBS Lett 1994; 353:124-8.
11. Suzuki M, Komiyama N, Itoh M et al. Purification, characterization and molecular cloning of Cha o 1, a major allergen of Chamaecyparis obtusa (Japanese cypress) pollen. Mol Immunol 1996; 33:451-60.
12. Mori T, Yokoyama M, Komiyama N, Okano M, Kino K. Purification, identification, and cDNA cloning of Cha o 2, the second major allergen of Japanese cypress pollen. Biochem Biophys Res Commun 1999; 263:166-71.
13. Ikagawa S, Matsushita S, Chen YZ, Ishikawa, Nishimura Y. Single amino acid substitutions on a Japanese cedar pollen allergen (Cry j I)-derived peptide induced alterations in human T cell responses and T cell receptor antagonism. J Allergy Clin Immunol 1996; 97:53-64.
14. Ishikawa T, Ikagawa S, Masuyama K, Matsushita S, Nishimura Y. Human T cell response to antigen peptides of Japanese cedar pollen (Cry j I). Int Arch Allergy Immunol 1997; 113:255-7.
15. Sone T, Morikubo K, Miyahara M et al. T cell epitopes in Japanese cedar (Cryptomeria japonica) pollen allergens: choice of major T cell epitopes in Cry j 1 and Cry j 2 toward design of the peptide-based immunotherapeutics for the management of Japanese cedar pollinosis. J Immunol 1998; 161:448-57.
16. Sone T, Morikubo K, Shimizu K, Komiyama N, Tsunoo H, Kino K. Peptide specificity, HLA class II restriction, and T-cell subsets of the T-cell clones specific to either Cry j 1 or Cry j 2, the major allergens of Japanese cedar (Cryptomeria japonica) pollen. Int Arch Allergy Immunol 1999; 119:185-96.
17. Ohno N, Ide T, Sakaguchi M, Inouye S, Saito S. Common antigenicity between Japanese cedar (Cryptomeria japonica) pollen, II. Determination of the cross-reacting T-cell epitopes of Cry j 1 and Cha o 1 in mice. Immunology 2000; 99:630-4.
18. Counsell CM, Bond JF, Ohman JL, Greenstein JL, Garman RD. Definition of the human T-cell epitopes of Fel d 1, the major allergen of the domestic cat. J Allergy Clin Immunol 1996; 98:884-94.
19. Hori T, Kamikawaji N, Kimura A et al. Japanese cedar pollinosis and HLA-DP5. Tissue Antigens 1996; 47:485-91.
20. Stern LJ, Brown JH, Jardetzky TS et al. Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide. Nature 1994; 368:215-21.
21. Hennecke J, Carfi A, Wiley DC. Structure of a covalently stabilized complex of a human αβ T-cell receptor, influenza HA peptide and MHC class II molecule, HLA-DR1. EMBO J 2000; 19:5611-24.
22. Rammensee HG, Friede T, Stevanovic S. MHC ligands and peptide motifs: first listing. Immunogenetics 1995; 41:178-228.
23. Alexander J, Snoke K, Ruppert J et al. Functional consequences of engagement of the T cell receptor by low affinity ligands. J Immunol 1993; 150:1-7.
24. Wedderburn LR, Searle SJM, Rees AR, Lamb JR, Owen MJ. Mapping T cell recognition: the identification of a T cell receptor residue critical to the specific interaction with an influenza hemagglutinin peptide. Eur J Immunol 1995; 25:1654-62.
25. Ebner C, Schenk S, Szépfalusi Z et al. Multiple T cell specificities for Bet v I, the major birch pollen allergen, within single individuals: studies using specific T cell clones and overlapping peptides. Eur J Immunol 1993; 23:1523-7.
26. Ebner C, Schenk S, Najafian N et al. Nonallergic individuals recognize the same T cell epitopes of Bet v 1, the major birch pollen allergen, as atopic patients. J Immunol 1995; 154:1932-40.
27. Spiegelberg HL, Beck L, Stevenson DD, Ishioka GY. Recognition of T cell epitopes and lymphokine secretion by rye glass allergen Lolium perenne-I specific human T cell clones. J Immunol 1994; 152:4706-11.
28. Schenk S, Briteneder H, Susani M et al. T-cell epitopes of Phl p 1, major pollen allergen of timothy grass (Phleum pratense): evidence for crossreacting and non-crossreacting T-cell epitopes within grass group I allergens. J Allergy Clin Immunol 1995; 96:986-96.
29. Würtzen PA, Bufe A, Wissenbach M et al. Identification of isoform-specific T-cell epitopes in the major timothy grass pollen allergen, Phl p 5. Clin Exp Allergy 1999; 29:1614-25.
30. Jahn-Schmid B, Kelemen P, Himly M et al. The T cell response to Art v 1, the major mugwort pollen allergen, is dominated by one Epitope. J Immunol 2002; 169:6005-11.
31. Fritsch R, Bohle B, Vollmann U et al. Bet v 1, the major birch pollen allergen, and Mal d 1, the major apple allergen, cross-react at the level of allergen-specific T helper cells. J Allergy Clin Immunol 1998; 102:679-86.
32. Bohle B, Radakovics A, Jahn-Schmid B et al. Bet v 1, the major birch pollen allergen, initiates sensitization to Api g 1, the major allergen in celery: evidence at the T cell level. Eur J Immunol 2003; 33:3303-10.
33. Midoro-Horiuti T, Goldblum RM, Kurosky A, Wood TG, Schein CH, Brooks EG. Molecular cloning of the mountain cedar (Juniperus ashei) pollen major allergen, Jun a 1. J Allergy Clin Immunol 1999; 104:613-7.
34. Midoro-Horiuti T, Goldblum RM, Brooks EG. Identification of mutations in the genes for the pollen allergen of eastern red cedar (Juniperus virginiana). Clin Exp Allergy 2001; 31: 771-8.
35. Aceituno E, Del Pozo V, Minguez A et al. Molecular cloning of major allergen from Cupressus arizonica pollen: cup a 1. Clin Exp Allergy 2000; 30:1750-8.
36. Midoro-Horiuti T, Mathura V, Schein CH et al. Major linear IgE epitopes of mountain cedar pollen Jun a 1 map to the pectate lyase catalytic site. Mol Immunol 2003; 40:555-62.