Mutational analysis does not support the existence of a putative tertiary structural element in the left terminal domain of Potato spindle tuber viroid

Journal of General Virology

Volumn 86, Issue 6, 2005, Pages 1835-1839

  Owens, Robert A ^a   Thompson, Susan M ^a  

^a AGRICULTURAL RESEARCH SERVICE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEOTIDE; VIRUS RNA;

ARTICLE; CONTROLLED STUDY; GENETIC SCREENING; IN VIVO STUDY; INOCULATION; MUTAGENESIS; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; POTATO SPINDLE TUBER; PRIORITY JOURNAL; PROGENY; RNA CONFORMATION; RNA TRANSCRIPTION; SEEDLING; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS; TOMATO; VIROID; VIRUS MORPHOLOGY; VIRUS VIRULENCE; WILD TYPE;

BASE SEQUENCE; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEIC ACID CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SOLANUM TUBEROSUM; VIROIDS;

LYCOPERSICON ESCULENTUM; POSPIVIROIDAE; POTATO SPINDLE TUBER VIROID; SOLANUM TUBEROSUM; VIROIDS;

EID: 20044387947     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.80869-0     Document Type: Article

References (16)

1. Baumstark, T., Schröder, A. R. W. & Riesner, D. (1997). Viroid processing: a switch from cleavage to ligation is driven by a change from a tetraloop to a loop E conformation. EMBO J 16, 599-610.
2. Dingley, A. J., Steger, G., Esters, B., Riesner, D. & Grzesiek S. (2003). Structural characterization of the 69 nucleotide potato spindle tuber viroid left-terminal domain by NMR and thermo-dynamic analysis. J Mol Biol 334, 751-767.
3. Gast, F.-U. (2003). A new structural motif in the left terminal domain of large viroids identified by covariation analysis. Virus Genes 26, 19-23.
4. Gast F.-U., Kempe, D., Spieker, R. L. & Säinger, H. L. (1996). Secondary structure probing of potato spindle tuber viroid (PSTVd) and sequence comparison with other small pathogenic RNA replicons provides evidence for central non-canonical base-pairs, large A-rich loops, and a terminal branch. J Mol Biol 262, 652-670.
5. Góra-Sochacka, A., Kierzek, A., Candresse, T. & Zagórski, W. (1997). The genetic stability of potato spindle tuber viroid (PSTVd) molecular variants. RNA 3, 68-74.
6. Hadidi, A., Flores, R., Randles, J. W. & Semancik, J. S. (editors) (2003). Viroids. Collingwood, Australia: CSIRO Publishing.
7. Keese, P. & Symons, R. H. (1985). Domains in viroids: evidence of intermolecular RNA rearrangements and their contribution to viroid evolution. Proc Natl Acad Sci U S A 82, 4582-4586.
8. Lück R., Gräf, S. & Steger, G. (1999). ConStruct: a tool for thermodynamic controlled prediction of conserved secondary structure. Nucleic Acids Res 27, 4208-4217.
9. Matoušek, J., Patzak, J., Orctová, L., Schubert, J., Vrba, L., Steger, G. & Riesner, D. (2001). The variability of hop latent viroid as induced upon heat treatment. Virology 287, 349-358.
10. Owens, R. A., Thompson, S. M. & Kramer, M. (2003). Identification of neutral mutants surrounding two naturally occurring variants of Potato spindle tuber viroid. J Gen Virol 84, 751-756.
11. Podleckis, E. V., Hammond, R. W., Hurtt, S. W. & Hadidi, A. (1993). Chemiluminescent detection of potato and pome fruit viroids by digoxygenin-labeled dot blot and tissue blot hybridization. J Virol Methods 43, 147-158.
12. Qu, F., Heinrich, C., Loss, P., Steger, G., Tien, P. & Riesner, D. (1993). Multiple pathways of reversion in viroids for conservation of structural elements. EMBO J 12, 2129-2139.
13. Stasys, R. A., Dry, I. B. & Rezaian, M. A. (1995). The termini of a new citrus viroid contain duplications of the central conserved regions from two viroid groups. FEBS Lett 358, 182-184.
14. Steger, G. & Riesner, D. (2003). Molecular characteristics. In Viroids, pp. 15-29. Edited by A. Hadidi, R. Flores, J. W. Randles & J. S. Semancik. Collingwood, Australia: CSIRO Publishing.
15. Wang, M.-B., Bian, X.-Y., Wu, L.-M. & 10 other authors (2004). On the role of RNA silencing in the pathogenicity and evolution of viroids and viral satellites. Proc Natl Acad Sci U S A 101, 3275-3280.
16. Woese, C. R. & Pace, N. R. (1993). Probing RNA structure, function, and history by comparative analysis. In The RNA World, pp. 91-117. Edited by R. F. Gesteland & J. F. Atkins. Plainview, NY: Cold Spring Harbor Press.