The Bacillus subtilis desaturase: A model to understand phospholipid modification and temperature sensing

Archives of Microbiology

Volumn 183, Issue 4, 2005, Pages 229-235

  Mansilla, María C ^a   De Mendoza, Diego ^a  

^a UNIVERSIDAD NACIONAL DE ROSARIO   (Argentina)

Author keywords

Desaturase topology; Regulation of membrane lipid synthesis; Signal transduction

Indexed keywords

PHOSPHOLIPID;

BACILLUS SUBTILIS; CONTROLLED STUDY; ENZYME PURIFICATION; GENE CONTROL; GENETIC TRANSCRIPTION; HOMEOSTASIS; LOW TEMPERATURE; MEMBRANE FLUIDITY; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY; SIGNAL TRANSDUCTION; SYNTHESIS; TEMPERATURE MEASUREMENT;

ADAPTATION, PHYSIOLOGICAL; BACILLUS SUBTILIS; FATTY ACID DESATURASES; PHOSPHOLIPIDS; TEMPERATURE;

BACILLUS SUBTILIS;

EID: 20044379064     PISSN: 03028933     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00203-005-0759-8     Document Type: Short Survey

References (41)

1. Aguilar PS, Cronan JE Jr, de Mendoza D (1998) A Bacillus subtilis gene induced by cold shock encodes a membrane phospholipid desaturase. J Bacteriol 180:2194-2200
2. Aguilar PS, López P, de Mendoza D (1999) Transcriptional control of the low-temperature-inducible des gene, encoding the Δ5 desaturase of Bacillus subtilis. J Bacteriol 181:7028-7033
3. Aguilar PS, Hernandez-Arriaga AM, Cybulski LE, Erazo AC, de Mendoza D (2001) Molecular basis of thermosensing: a two-component signal transduction thermometer in Bacillus subtilis. EMBO J 20:1681-1691
4. Albanesi D, Mansilla MC, de Mendoza D (2004) The membrane fluidity sensor DesK of Bacillus subtilis controls the signal decay of its cognate response regulator. J Bacteriol 186:2655-2663
5. Altabe SG, Aguilar PS, Caballero GM, de Mendoza D (2003) The Bacillus subtilis acyl lipid desaturase is a Δ5 desaturase. J Bacteriol 185:3228-3231
6. van Beilen JB, Penning D, Witholt B (1992) Topology of the membrane-bound alkane hydroxylase of Pseudomonas oleovorans. J Biol Chem 267:9194-9201
7. Bloch K (1963) The biological synthesis of unsaturated fatty acids. Biochem Soc Symp 24:1-16
8. Campbell JW, Cronan JE Jr (2001) Bacterial fatty acid biosynthesis: targets for antibacterial drug discovery. Annu Rev Microbiol 55:305-332
9. Cronan JE Jr, Gelmann EP (1973) An estimate of the minimum amount of unsaturated fatty acid required for growth of Escherichia coli. J Biol Chem 248:1188-1195
10. Cronan JE Jr, Rock CO (1987) Biosynthesis of membrane lipids. In: Neidhardt FC, Ingraham JL, Low KB, Magasanik B, Schaechter M, Umbarger HE (eds) Escherichia coli and Salmonella: cellular and molecular biology. ASM, Washington DC, pp 474-497
11. Cronan JE Jr, Gennis RB, Maloy SR (1987) Cytoplasmic membrane. In: Neidhardt FC, Ingraham JL, Low KB, Magasanik B, Schaechter M, Umbarger HE (eds) Escherichia coli and Salmonella: cellular and molecular biology. ASM, Washington DC, pp 31-55
12. Cybulski LE, Albanesi D, Mansilla MC, Altabe S, Aguilar PS, de Mendoza D (2002) Mechanism of membrane fluidity optimisation: isothermal control of the Bacillus subtilis acyl-lipid desaturase. Mol Microbiol 45:1379-1388
13. Cybulski LE, del Solar G, Craig PO, Espinosa M, de Mendoza D (2004) Bacillus subtilis DesR functions as a phosphorylation-activated switch to control membrane lipid fluidity. J Biol Chem 279:39340-39347
14. Díaz AR, Mansilla MC, Vila AJ, de Mendoza D (2002) Membrane topology of the acyl-lipid desaturase from Bacillus subtilis. J Biol Chem 277:48099-48106
15. English N, Palmer CNA, Alworth WL, Kang L, Hughes V, Wolf CR (1997) Fatty acid signals in Bacillus megaterium are attenuated by cytochrome P-450-mediated hydroxylation. Biochem J 327:363-368
16. Enoch HG, Catala A, Strittmatter P (1976) Mechanism of rat liver microsomal stearyl-CoA desaturase. Studies of the substrate specificity, enzyme-substrate interactions, and the function of lipid. J Biol Chem 251:5095-5103
17. Goldberg EM, Zidovetzki R (1997) Effects of dipalmitoylglycerol and fatty acids on membrane structure and protein kinase C activity. Biophys J 73:2603-2614
18. Grau R, de Mendoza D (1993) Regulation of the synthesis of unsaturated fatty acids by growth temperature in Bacillus subtilis. Mol Microbiol 8:535-542
19. Kaneda T (1991) Iso-fatty and anteiso-fatty acids in bacteria: biosynthesis, function, and taxonomic significance. Microbiol Rev 55:288-302
20. Klein W, Weber MH, Marahiel MA (1999) Cold shock response of Bacillus subtilis: isoleucine-dependent switch in the fatty acid branching pattern for membrane adaptation to low temperatures. J Bacteriol 181:5341-5349
21. Lindqvist Y, Huang W, Schneider G, Shanklin J (1996) Crystal structure of Δ9 stearoyl-acyl carrier protein desaturase from castor seed and its relationship to other di-iron proteins. EMBO J 15:4081-4092
22. Mansilla MC, Cybulski LE, Albanesi D, de Mendoza D (2004) Control of membrane lipid fluidity by molecular thermo-sensors. J Bacteriol 186:6681-6688
23. Marrakchi H, Choi KH, Rock CO (2002) A new mechanism for anaerobic unsaturated fatty acid formation in Streptococcus pneumoniae. J Biol Chem 277:44809-44816
24. Miquel M, James D Jr, Dooner H, Browse J (1993) Arabidopsis requires polyunsaturated lipids for low-temperature survival. Proc Natl Acad Sci USA 90:6208-6212
25. Murata N, Wada H (1995) Acyl-lipid desaturases and their importance in the tolerance and acclimatization to cold of cyanobacteria. Biochem J 308:1-8
26. Mustardy L, Los DA, Gombos Z, Murata N (1996) Immunocytochemical localization of acyl-lipid desaturases in cyanobacterial cells: evidence that both thylakoid membranes and cytoplasmic membranes are sites of lipid desaturation. Proc Natl Acad Sci USA 93:10524-10527
27. Ohlrogge J, Brownse J (1995) Lipid biosynthesis. Plant Cell 7:957-970
28. Phetsuksiri B, Jackson M, Scherman H, McNeil M, Besra GS, Baulard AR, Slayden RA, DeBarber AE, Barry CE III, Baird MS, Crick DC, Brennan PJ (2003) Unique mechanism of action of the thiourea drug isoxyl on Mycobacteruim tuberculosis. J Biol Chem 278:53123-53130
29. Sakamoto T, Murata N (2002) Regulation of the desaturation of fatty acids and its role in tolerance to cold and salt stress. Curr Opin Microbiol 5:208-210
30. Sasata RJ, Reed DW, Loewen MC, Covello PS (2004) Domain swapping localizes the structural determinants of regioselectivity in membrane-bound fatty acid desaturases of Caenorhabditis elegans. J Biol Chem 279:39296-39302
31. Shanklin J, Cahoon EB (1998) Desaturation and related modifications of fatty acids. Annu Rev Plant Physiol Plant Mol Biol 49:611-641
32. Shanklin J, Whittle E, Fox BG (1994) Eight histidine residues are catalytically essential in a membrane-associated iron enzyme, stearoyl-CoA desaturase, and are conserved in alkane hydroxylase and xylene monooxygenase. Biochemistry 33:12787-12794
33. Strauch, MA, de Mendoza D, Hoch JA (1992) Cis-unsaturated fatty acids specifically inhibit a signal-transducing protein kinase required for initiation of sporulation in Bacillus subtilis. Mol Microbiol 6:2909-2917
34. Stukey JE, McDonough VM, Martin CE (1990) The OLE gene of Saccharomyces cerevisiae encodes the Δ9 fatty acid desaturase and can be functionally replaced by the rat stearoyl-CoA desaturase gene. J Biol Chem 265:20144-20149
35. Suzuki I, Los DA, Kanesaki Y, Mikami K, Murata N (2000) The pathway for perception and transduction of low-temperature signals in Synechocystis. EMBO J 19:1327-1334
36. Tocher DR, Leaver MJ, Hodgson PA (1988) Recent advances in the biochemistry and molecular biology of fatty acyl desaturases. Prog Lipid Res 37:73-117
37. +-ATPase activity at suboptimal concentrations of ATP. Biol Pharm Bull 18:664-670
38. Wada H, Gombos Z, Murata N (1990) Enhancement of chilling tolerance of a cyanobacterium by genetic manipulation of fatty acid desaturation. Nature 347:200-203
39. Wallis JG, Browse J (2002) Mutants of Arabidopsis reveal many roles for membrane lipids. Prog Lipid Res 41:254-278
40. Weber MHW, Klein W, Muller L, Niess UM, Marahiel M (2001) Role of the Bacillus subtilis fatty acid desaturase in membrane adaptation during cold shock. Mol Microbiol 39:1321-1329
41. Yung BY, Kornberg A (1988) Membrane attachment activates DnaA protein, the initiation protein of chromosome replication in Escherichia coli. Proc Natl Acad Sci USA 19:7202-7205