Endurance exercise training in orthostatic intolerance: A randomized, controlled trial

Hypertension

Volumn 45, Issue 3, 2005, Pages 391-398

  Winker, Robert ^a   Barth, Alfred ^a   Bidmon, Daniela ^a   Ponocny, Ivo ^a   Weber, Michael ^a   Mayr, Otmar ^c   Robertson, David ^b   Diedrich, André ^b   Maier, Richard ^a   Pilger, Alex ^a   Haber, Paul ^a,b   Rüdiger, Hugo W ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b VANDERBILT UNIVERSITY   (United States)

^c Military Hospital Vienna   (Austria)

Author keywords

Autonomic nervous system; Catecholamines; Exercise training

Indexed keywords

NORADRENALIN;

ADULT; ARMY; ARTICLE; AUTONOMIC DYSFUNCTION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIZZINESS; EXERCISE; FATIGUE; HUMAN; MALE; NAUSEA; NORADRENALIN BLOOD LEVEL; ORTHOSTATIC DYSREGULATION; ORTHOSTATIC TACHYCARDIA; PRIORITY JOURNAL; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; SCREENING; STANDING; SYMPTOMATOLOGY; SYNDROME; TACHYCARDIA; TILT TABLE TEST;

ADULT; ALANINE; AUTONOMIC NERVOUS SYSTEM; CARDIOGRAPHY, IMPEDANCE; DNA; EXERCISE TEST; HEMODYNAMIC PROCESSES; HUMANS; HYPOTENSION, ORTHOSTATIC; JOGGING; MUTATION; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; PHYSICAL EDUCATION AND TRAINING; PHYSICAL ENDURANCE; PROLINE; SYMPORTERS; TREATMENT OUTCOME;

EID: 20044363096     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.0000156540.25707.af     Document Type: Article

References (54)

1. Winker R, Barth A, Dorner W, Mayr O, Pilger A, Ivancsits S, Ponocny I, Heider A, Wolf C, Rudiger HW. Diagnostic management of orthostatic intolerance in the workplace. Int Arch Occup Environ Health. 2003;76:143-150.
2. Winker R. Orthostatic intolerance-prevalence, diagnostic management and its significance for occupational medicine. Wien Klin Wochenschr. 2004;116(Suppl 1):40-46.
3. Wooley CF. Where are the diseases of yesteryear? DaCosta's syndrome, soldiers heart, the effort syndrome, neurocirculatory asthenia-and the mitral valve prolapse syndrome. Circulation. 1976;53:749-751.
4. Jacob G, Shannon JR, Black B, Biaggioni I, Mosqueda-Garcia R, Robertson RM, Robertson D. Effects of volume loading and pressor agents in idiopathic orthostatic tachycardia. Circulation. 1997;96:575-580.
5. Jacob G, Biaggioni I. Idiopathic orthostatic intolerance and postural tachycardia syndromes. Am J Med Sci. 1999;317:88-101.
6. Grubb BP, Klingenheben T. Postural orthostatic tachycardia syndrome (POTS): etiology, diagnosis and therapy. Med Klin (Munich). 2000;95:442-446.
7. Farrow S, Mers A, Banta G, Steigerwalt S, Lockette W. Effect of the alpha 2-adrenergic antagonist yohimbine on orthostatic tolerance. Hypertension. 1990;15:877-880.
8. Saltin B, Blomqvist G, Mitchell JH, Johnson RL. Jr., Wildenthal K, Chapman CB. Response to exercise after bed rest and after training. Circulation. 1968;38:VII1-VII78.
9. Farquhar WB, Taylor JA, Darling SE, Chase KP, Freeman R. Abnormal baroreflex responses in patients with idiopathic orthostatic intolerance. Circulation. 2000;102:3086-3091.
10. Minami N, Yoshikawa T, Kataoka H, Mori N, Nagasaka M, Kurosawa H, Kanazawa M, Kohzuki M. Effects of exercise and beta-blocker on blood pressure and baroreflexes in spontaneously hypertensive rats. Am J Hypertens. 2003;16:966-972.
11. Greenleaf JE, Sciaraffa D, Shvartz E, Keil LC, Brock PJ. Exercise training hypotension: implications for plasma volume, renin, and vasopressin. J Appl Physiol. 1981;51:298-305.
12. Raven PB, Pawelczyk JA. Chronic endurance exercise training: a condition of inadequate blood pressure regulation and reduced tolerance to LBNP. Med Sci Sports Exerc. 1993;25:713-721.
13. Smith ML, Raven PB. Cardiovascular responses to lower body negative pressure in endurance and static exercise-trained men. Med Sci Sports Exerc. 1986;18:545-550.
14. Convertino VA. Endurance exercise training: conditions of enhanced hemodynamic responses and tolerance to LBNP. Med Sci Sports Exerc. 1993;25:705-712.
15. Mtinangi BL, Hainsworth R. Increased orthostatic tolerance following moderate exercise training in patients with unexplained syncope. Heart. 1998;80:596-600.
16. Mtinangi BL, Hainsworth R. Effects of moderate exercise training on plasma volume, baroreceptor sensitivity and orthostatic tolerance in healthy subjects. Exp Physiol. 1999;84:121-130.
17. Gratze G, Fortin J, Labugger R, Binder A, Kotanko P, Timmermann B, Luft FC, Hoehe MR, Skrabal F. β-2 Adrenergic receptor variants affect resting blood pressure and agonist-induced vasodilation in young adult Caucasians. Hypertension. 1999;33:1425-1430.
18. Tschernko EM, Hofer S, Bieglmayer C, Wisser W, Haider W. Early postoperative stress: video-assisted wedge resection/lobectomy vs conventional axillary thoracotomy. Chest. 1996;109:1636-1642.
19. Shannon JR, Flattem NL, Jordan J, Jacob G, Black BK, Biaggioni I, Blakely RD, Robertson D. Orthostatic intolerance and tachycardia associated with norepinephrine-transporter deficiency. N Engl J Med. 2000;342:541-549.
20. Ivancsits S, Heider A, Rudiger HW, Winker R. Orthostatic intolerance is not necessarily related to a specific mutation (Ala457Pro) in the human norepinephrine transporter gene. Am J Med Sci. 2003;325:63-65.
21. Beitzke M, Pfister P, Fortin J, Skrabal F. Autonomic dysfunction and hemodynamics in vitamin B12 deficiency. Auton Neurosci. 2002;97:45-54.
22. Fortin J, Habenbacher W, Gruellenberger R, Wach P, Skrabal F. Real-time Monitor for hemodynamic beat-to-beat parameters and power spectra analysis of the biosignals. 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society; 1998.
23. Kubicek WG, Karnegis JN, Patterson RP, Witsoe DA, Mattson RH. Development and evaluation of an impedance cardiac output system. Aerosp Med. 1966;37:1208-1212.
24. Schloegl A, Flotzinger D, Furtscheller G. Adaptive autoregressive modeling used for single trial EEG classification. Biomed Technik. 1997;42:162-167.
25. Bianchi A, Mainardi L, Meloni C, Chierchia S, Cerutti S. Continuous monitoring of the Sympatho-Vagal Balance through spectral analysis. IEEE Engineering in Medicine and Biology. 1997:64-73.
26. Heart rate variability. Standards of measurement, physiological interpretation, and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Eur Heart J. 1996;17:354-381.
27. Böhm H, Bürklen R, Dienstl F, Ehrenböck G, Gaul W, Herbinger E, Kiss E, Kubicek F, Kühn P, Kummer F, Niederberger M, Schlick W. Empfehlungen für eine standardisierte Ergometrie. Öst Ärzteztg. 1978;33:333-344.
28. Convertino VA, Thompson CA, Eckberg DL, Fritsch JM, Mack GW, Nadel ER. Baroreflex responses and LBNP tolerance following exercise training. Physiologist. 1990;33:S40-41.
29. Pawelczyk JA, Zuckerman JH, Blomqvist CG, Levine BD. Regulation of muscle sympathetic nerve activity after bed rest deconditioning. Am J Physiol Heart Circ Physiol. 2001;280:H2230-H2239.
30. Ogoh S, Volianitis S, Nissen P, Wray DW, Secher NH, Raven PB. Carotid baroreflex responsiveness to head-up tilt-induced central hypovolaemia: effect of aerobic fitness. J Physiol. 2003;551:601-608.
31. Ten Harkel AD, Van Lieshout JJ, Van Lieshout EJ, Wieling W. Assessment of cardiovascular reflexes: influence of posture and period of preceding rest. J Appl Physiol. 1990;68:147-153.
32. Streeten DH, Anderson GH, Jr. Delayed orthostatic intolerance. Arch Intern Med. 1992;152:1066-1072.
33. Lamarre-Cliche M, Cusson J. The fainting patient: value of the head-upright tilt-table test in adult patients with orthostatic intolerance. CMAJ. 2001;164:372-376.
34. El-Sayed H, Hainsworth R. Salt supplement increases plasma volume and orthostatic tolerance in patients with unexplained syncope. Heart. 1996;75:134-140.
35. Low PA, Opfer-Gehrking TL, Textor SC, Schondorf R, Suarez GA, Fealey RD, Camilleri M. Comparison of the postural tachycardia syndrome (POTS) with orthostatic hypotension due to autonomic failure. J Auton Nerv Syst. 1994;50:181-188.
36. Furlan R, Piazza S, Dell'Orto S, Gentile E, Cerutti S, Pagani M, Malliani A. Early and late effects of exercise and athletic training on neural mechanisms controlling heart rate. Cardiovasc Res. 1993;27:482-488.
37. Pagani M, Somers V, Furlan R, Dell'Orto S, Conway J, Baselli G, Cerutti S, Sleight P, Malliani A. Changes in autonomic regulation induced by physical training in mild hypertension. Hypertension. 1988;12:600-610.
38. Akselrod S, Gordon D, Madwed JB, Snidman NC, Shannon DC, Cohen RJ. Hemodynamic regulation: investigation by spectral analysis. Am J Physiol. 1985;249:H867-H875.
39. Eckberg DL. Sympathovagal balance: a critical appraisal. Circulation. 1997;96:3224-3232.
40. Furlan R, Jacob G, Snell M, Robertson D, Porta A, Harris P, Mosqueda-Garcia R. Chronic orthostatic intolerance: a disorder with discordant cardiac and vascular sympathetic control. Circulation. 1998;98:2154-2159.
41. Piccirillo G, Fimognari FL, Viola E, Marigliano V. Age-adjusted normal confidence intervals for heart rate variability in healthy subjects during head-up tilt. Int J Cardiol. 1995;50:117-124.
42. Winker R, Barth A, Valic E, Maier R, Pilger A, Osterode W, Rüdiger HW. Functional adrenergic receptor polymorphisms and idiopathic orthostatic intolerance. Int Arch Occup Environ Health. In press.
43. Slordahl SA, Madslien VO, Stoylen A, Kjos A, Helgerud J, Wisloff U. Atrioventricular plane displacement in untrained and trained females. Med Sci Sports Exerc. 2004;36:1871-1875.
44. Hollman W, Hettinger T. Sportmedizin: Grundlagen für Arbeit, Training und Präventionsmedizin. Stuttgart: Schattauer; 2000.
45. Iwasaki K, Zhang R, Zuckerman JH, Levine BD. Dose-response relationship of the cardiovascular adaptation to endurance training in healthy adults: how much training for what benefit? J Appl Physiol. 2003;95:1575-1583.
46. Portier H, Louisy F, Laude D, Berthelot M, Guezennec CY. Intense endurance training on heart rate and blood pressure variability in runners. Med Sci Sports Exerc. 2001;33:1120-1125.
47. Ueno LM, Moritani T. Effects of long-term exercise training on cardiac autonomic nervous activities and baroreflex sensitivity. Eur J Appl Physiol. 2003;89:109-114.
48. Khurana RK. Orthostatic intolerance and orthostatic tachycardia: a heterogeneous disorder. Clin Auton Res. 1995;5:12-18.
49. Busjahn A, Voss A, Knoblauch H, Knoblauch M, Jeschke E, Wessel N, Bohlender J, McCarron J, Faulhaber HD, Schuster H, Dietz R, Luft FC. Angiotensin-converting enzyme and angiotensinogen gene polymorphisms and heart rate variability in twins. Am J Cardiol. 1998;81:755-760.
50. Hassan MO, Albarwani S, Al Yahaee S, Comuzzie AG, Bayoum RA. The Heritabilty of haemodynamic variables contributing to blood pressure in a large omani pedigree: first report of the Nizwablood pressure study [abstract]. Clin Auton Res. 2003;13:64.
51. Jordan J, Shannon JR, Jacob G, Pohar B, Robertson D. Interaction of genetic predisposition and environmental factors in the pathogenesis of idiopathic orthostatic intolerance. Am J Med Sci. 1999;318:298-303.
52. Robertson D. Genetics and molecular biology of hypotension. Curr Opin Nephrol Hypertens. 1994;3:13-24.
53. Tabara Y, Kohara K, Miki T. Polymorphisms of genes encoding components of the sympathetic nervous system but not the renin-angiotensin system as risk factors for orthostatic hypotension. J Hypertens. 2002;20:651-656.
54. Sandroni P, Opfer-Gehrking TL, McPhee BR, Low PA. Postural tachycardia syndrome: clinical features and follow-up study. Mayo Clin Proc. 1999;74:1106-1110.