Graves' disease in interferon-α-treated and untreated patients with chronic hepatitis C virus infection

Journal of Investigative Medicine

Volumn 53, Issue 1, 2005, Pages 26-30

  Minelli, Roberta ^a,d   Coiro, Vittorio ^b   Valli, Maria Antonietta ^c   Finardi, Lorenzo ^a   Di Secli, Clelia ^a   Bertoni, Roberto ^c   La Gioia, Daniele ^b   Barilli, Angela Luciana ^b   Ferrari, Carlo ^c   Jotti, Gloria Saccani ^b   Delsignore, Roberto ^b  

^a UNIVERSITY OF PARMA MEDICAL SCHOOL   (Italy)

^b UNIVERSITY OF PARMA   (Italy)

^c UNIVERSITY HOSPITAL OF PARMA   (Italy)

^d Cattedra di Endocrinologia   (Italy)

Author keywords

Chronic hepatitis C; Graves' disease; Interferon therapy

Indexed keywords

HUMAFERON; LIOTHYRONINE; LYMPHOBLAST INTERFERON; PEGINTERFERON ALPHA2B; RECOMBINANT ALPHA INTERFERON; RECOMBINANT ALPHA2B INTERFERON; RIBAVIRIN; THIAMAZOLE; THYROGLOBULIN ANTIBODY; THYROID PEROXIDASE ANTIBODY; THYROTROPIN; THYROXINE; ALPHAN1 INTERFERON;

ADULT; ARTICLE; CHRONIC HEPATITIS; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; FEMALE; GRAVES DISEASE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; IODINE 131 UPTAKE TEST; MALE; PATHOGENESIS; THYROID FUNCTION; ANTIVIRAL THERAPY; CHRONIC HEPATITIS C; EUTHYROIDISM; FREE LIOTHYRONINE INDEX; FREE THYROXINE INDEX; MIDDLE AGED; OUTCOME ASSESSMENT; THYROTROPIN BLOOD LEVEL;

HEPATITIS C VIRUS;

EID: 19944431449     PISSN: 17088267     EISSN: None     Source Type: Journal    
DOI: 10.2310/6650.2005.00002     Document Type: Article

References (20)

1. Vial T, Descotes J. Clinical toxicity of the interferons. Drug Saf 1994;10:115-50.
2. Marcellin P, Pouteau M, Benhamou JP. Hepatits C virus infection, alpha interferon therapy and thyroid dysfunction. J Hepatol 1995;22:364-9.
3. Imagawa A, Itoh N, Hanafusa T, et al. Autoimmune endocrine disease induced by recombinant interferon-α therapy for chronic active type C hepatitis. J Clin Endocrinol Metab 1995;80:922-6.
4. Koh LKH, Greenspan FS, Yeo PPB. Interferon-α induced thyroid dysfunction: three clinical presentations and a review of the literature. Thyroid 1997;7:891-6.
5. Prummel MF, Laurberg P. Interferon-α and autoimmune thyroid disease. Thyroid 2003;6:547-51.
6. Wong V, Fu AX-L, George J, Cheung NW. Thyrotoxicosis induced by alpha-interferon therapy in chronic viral hepatitis. Clin Endocrinol 2002;56:793-8.
7. Fattovich G, Giustina G, Favarato S, Ruol A, Investigators of the Italian Association for the Study of the Liver. A survey of adverse events in 11241 patients with chronic viral hepatitis treated with alfa interferon. J Hepatol 1996;24:38-47.
8. Kakizaki S, Takagi H, Murakami M, et al. HLA antigens in patients with interferon-α induced autoimmune thyroid disorders in chronic hepatitis C. J Hepatol 1999;30:794-800.
9. Carella C, Mazziotti G, Amato G, et al. Interferon-α-related thyroid disease: pathophysiological, epidemiological and clinical aspects. J Clin Endocrinol Metab 2004;89:3656-61.
10. Roti E, Minelli R, Giuberti T, et al. Multiple changes in thyroid function in patients with chronic active HCV hepatits treated with recombinant interferon-alpha. Am J Med 1996;172:482-7.
11. Leri O, Sinopoli MT, Di Prima MA, Paggi A. Hepatitis C virus antibodies and Graves' disease. BMJ 1995;310:128-9.
12. Antonelli A, Ferri C, Pampana A, et al. Thyroid disorders in chronic hepatitis C. Am J Med 2004;117:10-3.
13. Schattner A. Interferons and autoimmunity. Am J Med Sci 1988;295:532-44.
14. Yamazaki K, Kanaji Y, Shizume K, et al. Reversible inhibition by interferons alpha and beta of 1251 incorporation and thyroid hormone release by human thyroid follicles in vitro. J Clin Endocrinol Metab 1993;77:1439-41.
15. Preziati D, La Rosa L, Covini G, et al. Autoimmunity and thyroid function in patients with chronic active hepatitis treated with recombinant interferon alpha-2a. Eur J Endocrinol 1995;132:587-93.
16. Custro N, Montalto G, Scafidi V, et al. Prospective study on thyroid autoimmunity and dysfunction related to chronic hepatitis C and interferon therapy. J Endocrinol Invest 1997;20:374-80.
17. Loviselli A, Oppo A, Velluzzi F, et al. Independent expression of serological markers of thyroid autoimmunity and hepatic virus C infection in the general population: results of a community-based study in north-western Sardinia. J Endocrinol Invest 1999;22:660-5.
18. Metcalfe RA, Ball G, Kudesia G, Weetman AP. Failure to find an association between hepatitis C virus and thyroid autoimmunity. Thyroid 1997;7:421-4.
19. Marazuela M, Garcia-Buey L, Gonzalez-Fernandez B, et al. Thyroid autoimmune disorders in patients with chronic hepatitis C before and during interferon - a therapy. Clin Endocrinol (Oxf) 1996;44:635-42.
20. Weetman AP, McGregor AM. Autoimmune thyroid disease: further developments in our understanding. Endocr Rev 1994;15:788-830.