Synthesis and brain regional distribution of [11C]NPS 1506 in mice and rat: An N-methyl-D-aspartate (NMDA) receptor antagonist

Biological and Pharmaceutical Bulletin

Volumn 26, Issue 11, 2003, Pages 1570-1573

  Fuchigami, Takeshi ^a   Haradahira, Terushi ^b,c   Arai, Takuya ^b,c   Okauchi, Takashi ^b,c   Maeda, Jun ^b,c   Suzuki, Kazutoshi ^b   Yamamoto, Fumihiko ^a,c   Suhara, Tetsuya ^b,c   Sasaki, Shigeki ^a,c   Maeda, Minoru ^a,c  

^a KYUSHU UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Brain distribution; Carbon 11; N methyl D aspartate (NMDA) receptor; NPS 1506

Indexed keywords

3,3 BIS(3 FLUOROPHENYL) N METHYLPROPYLAMINE C 11; METHYL IODIDE C 11; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; RADIOPHARMACEUTICAL AGENT; SODIUM HYDROXIDE; UNCLASSIFIED DRUG; 3,3 BIS(3 FLUOROPHENYL) N METHYLPROPYLAMINE; AMINO ACID RECEPTOR BLOCKING AGENT; CARBON; FLUOROBENZENE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD LEVEL; BRAIN REGION; CONTROLLED STUDY; IN VITRO STUDY; IN VIVO STUDY; MALE; METHYLATION; MOUSE; NONHUMAN; RADIATION DOSE; RADIOCHEMISTRY; RAT; RODENT; SYNTHESIS; ANIMAL; BRAIN; DRUG ANTAGONISM; METABOLISM; SPRAGUE DAWLEY RAT;

ANIMALS; BRAIN; CARBON RADIOISOTOPES; EXCITATORY AMINO ACID ANTAGONISTS; FLUOROBENZENES; MALE; MICE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 19944431375     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.26.1570     Document Type: Article

References (17)

1. Brauner-Osborne H., Egebjerg J., Nielsen E. O., Madsen U., Krogsgaard-Larsen P., J. Med. Chem., 43, 2609-2645 (2000).
2. Kemp J. A., Mckernan R. M., Nature Neurosci. Suppl., 5, 1039-1042 (2002).
3. Moe S. T., Shimizu S. M., Smith D. L., Van Wagenen B. C., DelMar E. G., Balandrin M. F., Chien Y. (E)., Raszkiewicz J. L., Artman L. D., Mueller A. L., Lobkovsky E., Clardy J., Bioorg. Med. Chem. Lett., 9, 1915-1920 (1999).
4. Moe S. T., Smith D. L., DelMar E. G., Shimizu S. M., Van Wagenen B. C., Balandrin M. F., Chien Y. (E)., Raszkiewicz J. L., Artman L. D., White H. S., Mueller A. L., Bioorg. Med. Chem. Lett., 10, 2411-2415 (2000).
5. Mueller A. L., Artman L. D., Balandrin M. F., Brady E., Chien Y. (E)., DelMar E. G., George K., Kierstead A., Marriott T. B., Moe S. T., Newman M. K., Raszkiewicz, J. L., Sanguinetti E. L., Van Wagenen B. C., Wells D., Ann. N.Y. Acad. Sci., 890, 450-461 (1999).
6. Gibson R. E., Burns H. D., Hamill T. G., Eng W., Francis B. E., Ryan C., Curr. Pharm. Design, 6, 973-989 (2000).
7. Suzuki K., Inoue O., Hashimoto K., Yamasaki T., Kuchiki M., Tamate K., Appl. Radiat. Isot., 36, 971-976 (1985).
8. Moe S. T., Smith D. L., By K., Egan J. A., Filer C. N., J. Labelled Compds. Radiopharm., 41, 535-543 (1998).
9. Okauchi T., Suhara T., Maeda J., Kawabe K., Obayashi S., Suzuki K., Synapse, 41, 87-95 (2001).
10. Griecok P. A., Bahsas A., J. Org. Chem., 52, 5746-5749 (1987).
11. Wong E. H. F., Knight A. R., Woodruff G. N., J. Neurochem., 50, 274-281 (1988).
12. Ferrarese C., Guidotti A., Costa E., Miletich R. S., Rice K. C., de Costa B. R., Fulham M. J., Di Chiro G., Neuropharmacol., 30, 899-905 (1991).
13. Chen N., Luo T., Raymond L. A., J. Neurosci., 19, 6844-6854 (1999) and references cited therein.
14. Wüllner U., Young A. B., Penney J. B., Beal M. F., J. Neurochem., 63, 1772-1781 (1994).
15. Calculated value using Advanced Chemistry Development (ACD) Software Solaris V4.67, which is shown in STN databases.
16. Danysz W., Parsons C. G., Pharmacol. Rev., 50, 597-664 (1998).
17. Winchell H. S., Horst W. D., Braun L., Oldendorf W. H., Hattner R., Parker H., J. Nucl. Med., 21, 947-952 (1980).